Patents by Inventor Edward John Macarak

Edward John Macarak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF USING MEK INHIBITOR TO PREVENT RADIATION INDUCED FIBROSIS
    Publication number: 20210260066
    Abstract: A method of reducing the severity of radiation induced fibrosis (RIF) by administering to a patient at least a first dose of an MeK inhibitor such as trametinib between 0.01 mg to 2.0 mg, and after said radiation procedure, administering to said patient a further dose of the MeK inhibitor between 0.01 mg and 2.0 mg after the radiation procedure.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 26, 2021
    Applicant: Thomas Jefferson University
    Inventors: Joel ROSENBLOOM, Edward John MACARAK
  • TRAMETINIB PREVENTS MESOTHELIAL-MESENCHYMAL TRANSITION AND AMELIORATES ABDOMINAL ADHESION AND PULMONARY FIBROSIS FORMATION
    Publication number: 20200046708
    Abstract: A method of reducing the severity of abdominal adhesion due to surgical complications comprising: administering to said patient at least a first dose of trametinib between 0.01 mg to 2.0 mg, and after said surgical procedure, administering to said patient a further dose of trametinib between 0.01 mg to 2.0 mg, daily, for at least seven days post-surgery.
    Type: Application
    Filed: April 20, 2018
    Publication date: February 13, 2020
    Applicant: Thomas Jefferson University
    Inventors: Joel Rosenbloom, Edward John Macarak