Abstract: The invention provides a medical device having a thermostat for temperature measurement, irrigation/aspiration ports for fluid exchange and application of therapeutic modalities, a pressure manometer for pressure measurement, and an external system for control of temperature, pressure, and flow rate. When applied to the eye, eyelid and orbit, this device can be used in hypothermia or hyperthermia applications, the control of intraocular pressure (IOP), and the application of treatment modalities. Methods of using the device in treating patients suffering from central retinal artery occlusion, anterior optic nerve disease, pathology of the choroid and retina including the macula, inflammation of the eye including the vitreous and anterior segment, glaucoma, inflammation and/or infections of the anterior and/or posterior segment of the eye, treatment before/during/after surgery of the eye, and the application of treatment modalities including iontophoresis through a semi-permeable membrane are described.

Abstract: The invention provides a medical device having a thermister for temperature measurement, irrigation/aspiration ports for fluid exchange and application of therapeutic modalities, a pressure manometer for pressure measurement, and an external system for control of temperature, pressure, and flow rate. When applied to the eye and orbit, this device can be used in hypothermia or hyperthermia applications, the control of intraocular pressure (IOP), and the application of treatment modalities. Methods of using the device in treating patients suffering from central retinal artery occlusion, anterior optic nerve disease, pathology of the choroid and retina including the macula, inflammation of the eye including the vitreous and anterior segment, glaucoma, inflammation and/or infections of the anterior and/or posterior segment of the eye, treatment before/during/after surgery of the eye, and the application of treatment modalities through a semi-permeable membrane are described.

Abstract: Extremely non-homogenous high but extremely intense high fringe magnetic fields are purposefully (and even advantageously) utilized for magnetic resonance imaging (including localization and spectroscopy) so as to better obtain advantages typically associated with ultra high field MRI. Static magnetic field gradients inherently included in such fringe fields are actively utilized in conjunction with suitable NMR RF nutation pulses so as to achieve volume-selective NMR data acquisition. Special arrangements of static electromagnets, magnetic gradient coils and/or RF coils may be used in conjunction with novel RF/gradient pulse sequences so as to elicit and acquire suitable MRI data.

Abstract: A greatly reduced number of scintillation cyrstal/PMT gamma ray detectors are employed in a ring array about a PET image volume. Because of the relatively small number of such detectors, the complexity and expense of associated electronic signal processing channels is greatly reduced (even if each such channel is provided with sophisticated time of flight capabilities). Similarly, because relatively fewer crystals are employed, it becomes possible to use much larger and faster response time scintillation crystals so as to greatly increase gamma ray detection efficiency and scatter rejection while also permitting the electronic circuits to better reject random events and to provide effective time of flight image data filtering.