Patents by Inventor EDWARD KARPMAN

EDWARD KARPMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12502195
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: June 24, 2024
    Date of Patent: December 23, 2025
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Publication number: 20250281737
    Abstract: One embodiment comprises a tubular, expandable metal mesh outside of a Foley catheter, which is held in place during treatment with a bladder balloon. The mesh is compressed for insertion into the prostate. The mesh is then expanded so that at least a portion of the mesh is against the prostatic urethral wall. The mesh is treated with a medicament, such as paclitaxel. Urine may flow through the catheter since there is no blockage of the urethra. Embodiments use different elements and methods for compressing or expanding the metal mesh. The mesh in a passive state may be either compressed or expanded. The state if the mesh is changed by either pushing or pulling on the mesh while it is in place in the urethra. Other embodiments may use the metal mesh as one electrode for iontophoresis or electroporation.
    Type: Application
    Filed: March 9, 2024
    Publication date: September 11, 2025
    Inventors: Neal A Scott, Mark McElligott, Edward Karpman
  • Publication number: 20240407799
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Application
    Filed: June 24, 2024
    Publication date: December 12, 2024
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
  • Patent number: 12053202
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: August 6, 2024
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Patent number: 11903606
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 20, 2024
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Publication number: 20220257274
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 18, 2022
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
  • Patent number: 11350963
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 7, 2022
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Publication number: 20190380730
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Application
    Filed: August 29, 2019
    Publication date: December 19, 2019
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
  • Patent number: 10448966
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: October 22, 2019
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Publication number: 20170231655
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Application
    Filed: December 22, 2016
    Publication date: August 17, 2017
    Inventors: NIKOLAI ALJURI, EDWARD KARPMAN, CHRIS DANEK