Patents by Inventor EDWARD KARPMAN
EDWARD KARPMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12502195Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: GrantFiled: June 24, 2024Date of Patent: December 23, 2025Assignee: PROCEPT BioRobotics CorporationInventors: Nikolai Aljuri, Edward Karpman, Chris Danek
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Publication number: 20250281737Abstract: One embodiment comprises a tubular, expandable metal mesh outside of a Foley catheter, which is held in place during treatment with a bladder balloon. The mesh is compressed for insertion into the prostate. The mesh is then expanded so that at least a portion of the mesh is against the prostatic urethral wall. The mesh is treated with a medicament, such as paclitaxel. Urine may flow through the catheter since there is no blockage of the urethra. Embodiments use different elements and methods for compressing or expanding the metal mesh. The mesh in a passive state may be either compressed or expanded. The state if the mesh is changed by either pushing or pulling on the mesh while it is in place in the urethra. Other embodiments may use the metal mesh as one electrode for iontophoresis or electroporation.Type: ApplicationFiled: March 9, 2024Publication date: September 11, 2025Inventors: Neal A Scott, Mark McElligott, Edward Karpman
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Publication number: 20240407799Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: ApplicationFiled: June 24, 2024Publication date: December 12, 2024Applicant: PROCEPT BioRobotics CorporationInventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
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Patent number: 12053202Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: GrantFiled: April 29, 2022Date of Patent: August 6, 2024Assignee: PROCEPT BioRobotics CorporationInventors: Nikolai Aljuri, Edward Karpman, Chris Danek
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Patent number: 11903606Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: GrantFiled: April 29, 2022Date of Patent: February 20, 2024Assignee: PROCEPT BioRobotics CorporationInventors: Nikolai Aljuri, Edward Karpman, Chris Danek
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Publication number: 20220257274Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: ApplicationFiled: April 29, 2022Publication date: August 18, 2022Applicant: PROCEPT BioRobotics CorporationInventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
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Patent number: 11350963Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: GrantFiled: August 29, 2019Date of Patent: June 7, 2022Assignee: PROCEPT BioRobotics CorporationInventors: Nikolai Aljuri, Edward Karpman, Chris Danek
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Publication number: 20190380730Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: ApplicationFiled: August 29, 2019Publication date: December 19, 2019Applicant: PROCEPT BioRobotics CorporationInventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
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Patent number: 10448966Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: GrantFiled: December 22, 2016Date of Patent: October 22, 2019Assignee: PROCEPT BioRobotics CorporationInventors: Nikolai Aljuri, Edward Karpman, Chris Danek
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Publication number: 20170231655Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.Type: ApplicationFiled: December 22, 2016Publication date: August 17, 2017Inventors: NIKOLAI ALJURI, EDWARD KARPMAN, CHRIS DANEK