Abstract: A system and method for selecting a client gateway device to establish a path between client devices is provided. A method includes receiving a communication invitation directed to a first communication endpoint of a first client device in a first geographic region from a second client device in a second geographic region, the communication invitation pertaining to a real-time media communication, identifying a first client gateway device and a second client gateway device that are each associated with the first communication endpoint of the first client device, selecting one of the first client gateway device or the second client gateway device based on one or more selection criteria, and causing a communication path to be established between the second client device and the first client device via the selected client gateway device.

Abstract: A fishhook carrying device has a resilient prismatic block, of which two adjacent faces are cut into by at least one set of spaced grooves extending along a longest dimension thereof. Two opposite parallel grooveless faces thereof abut two rigid exterior walls, which, along with a connecting bottom wall, form a unitary box structure. Rigid exterior walls of either side of the box structure maintain the prismatic block in a compressed form such that interior walls of each groove are pressed against each other in a first resting condition. When a flange is inserted into a pressed groove, the interior walls of the groove resiliently separate and thereafter abut the flange, frictionally holding the flange in place. The interior groove walls return to the first resting condition upon removal of the flange from the device.

Abstract: A system and method for selecting a client gateway device to establish a path between client devices is provided. A method includes associating a first client gateway device of a first geographic region and a second client gateway device of a second geographic region with a first communication endpoint of a first client device, and associating a third client gateway device with a second client device, wherein the third client gateway device is a gateway of the first geographic region. The method also includes receiving a communication invitation directed to the first communication endpoint from the second client device via the third client gateway device, and responsive to receiving the communication invitation, selecting one of the first client gateway device or the second client gateway device. The method further includes establishing a communication path between the second client device and the first client device via the selected client gateway device and the third client gateway device.

Abstract: This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.

Abstract: Various examples described herein support or provide for data ingesting, aggregating, and organizing in one centralized location; enhancing data through data enrichment and artificial intelligence and machine learning automation into tailored recommendations; and distributing and integrating data into channels that help facilitating data exchange based on individual needs and/or third-party solutions.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: A system and method for selecting a client gateway device to establish a path between client devices is provided. A method includes associating a first client gateway device of a first geographic region and a second client gateway device of a second geographic region with a first communication endpoint of a first client device, and associating a third client gateway device with a second client device, wherein the third client gateway device is a gateway of the first geographic region. The method also includes receiving a communication invitation directed to the first communication endpoint from the second client device via the third client gateway device, and responsive to receiving the communication invitation, selecting one of the first client gateway device or the second client gateway device. The method further includes establishing a communication path between the second client device and the first client device via the selected client gateway device and the third client gateway device.

Abstract: This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.

Abstract: A system for predicting machine failure may include a controller for controlling a machine, a plurality of sensors, a plugin device, a first computing device, a second computing device, and/or a third computing device. The sensors and/or the plugin device may be communicatively coupled to the controller. The first computing device may be communicatively coupled to the plugin device. The plugin device may transmit data associated with the machine to the first computing device. The first computing device may execute at least one low fidelity model to determine an interesting event associated with the machine. The second computing device may be communicatively coupled to the first computing device. The first computing device may transmit data associated with the interesting event to the second computing device. The second computing device may execute at least one high fidelity model to determine a machine failure prediction.

Abstract: A system and method for regional routing of internet protocol based real-time communication that includes registering a set of client application endpoint routes, comprising registering at least a first client gateway route of a first endpoint in a first region; receiving a communication invitation of the first endpoint; processing a set of communication instructions associated with the communication invitation and identifying a set of communication resources and at least a second endpoint; querying the client application endpoint routes and identifying a client gateway route of the second endpoint; and dynamically directing signaling path and media path of the communication according to the regional availability of the communication resources, the client gateway route of the first endpoint, and client gateway instance route of the second endpoint.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: This invention relates to the field of genetic engineering. Specifically, the invention relates to the construction of operons to produce biologically active agents. For example, operons may be constructed to produce agents that control the function of biochemical pathway proteins (e.g., protein phosphatases, kinases and/or proteases). Such agents may include inhibitors and modulators that may be used in studying or controlling phosphatase function associated with abnormalities in a phosphatase pathway or expression level. Fusion proteins, such as light activated protein phosphatases, may be genetically encoded and expressed as photoswitchable phosphatases. Systems are provided for use in controlling phosphatase function within living cells or in identifying small molecule inhibitors/activator/modulator molecules of protein phosphatases associated with cell signaling.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: Access to sensitive information in a database can be restricted to improve security and enable efficient auditing. A security engine receives a request from a requesting entity to access data in the database and determines that the requested data includes sensitive information. In response to the requesting entity being authorized to access the data, the security engine retrieves the requested data from the database and modifies the retrieved data by modifying metadata of the retrieved data to include a tag indicating that the retrieved data includes sensitive information. The security engine provides the modified data to the requesting entity and modifies a data access log to identify each attempted access to the modified data. When sensitive data is requested, an interface can include an obscuring element, requiring a user to manually select the element to view the data, enabling the logging of the explicit access request by the user.

Abstract: A system and method for communicating with a client application that can include establishing a client signaling communication channel with a first client application; receiving a communication request from the first client application through the client signaling communication channel, wherein the communication request contains at least an authentication token and a specified communication destination; verifying the authentication token; if the authentication token is verified, at the system bridge, establishing a signaling communication channel with the communication destination and a second media communication channel with the specified communication destination; at the system bridge, establishing a first media communication channel with the client application; and merging the first media communication channel with the second media communication channel.