Patents by Inventor Edward L. Halk

Edward L. Halk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fully human antibodies against human 4-1BB
    Patent number: 7288638
    Abstract: Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: October 30, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Maria Jure-Kunkel, Laura J. Hefta, Marc Santoro, Subinay Ganguly, Edward L. Halk
  • Transgenic transchromosomal rodents for making human antibodies
    Patent number: 7041870
    Abstract: The present invention provides novel transgenic nonhuman mammals capable of producing human sequence antibodies, as well as methods of producing and using these antibodies.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: May 9, 2006
    Assignees: Medarex, Inc., Kirin Brewery Company Limited
    Inventors: Kazuma Tomizuka, Isao Ishida, Nils Lonberg, Edward L. Halk
  • Human CTLA-4 antibodies
    Patent number: 6984720
    Abstract: The present invention provides human sequence antibodies against CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: January 10, 2006
    Assignee: Medarex, Inc.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human CTLA-4 antibodies and their uses
    Publication number: 20020086014
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: September 7, 2001
    Publication date: July 4, 2002
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg