Patents by Inventor Edward M. Alderman

Edward M. Alderman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microtitre plate with a relieved perimeter
    Patent number: 7527769
    Abstract: A microtitre plate having a relieved perimeter includes a plate defining a plurality of wells and the perimeter of the plate is horizontally relieved. Alternatively, a microtitre plate may include a base and a holding section extending from the base. The holding section defines a plurality of wells and the perimeter thereof being horizontally relieved.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: May 5, 2009
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Richard P. Bunch, Frederick D. Simmons, Edward M. Alderman
  • Antibodies to angiogenin: immunotherapeutic agents
    Patent number: 5520914
    Abstract: This invention relates to the production of antibodies to angiogenin or to fragments thereof and to methods of inhibiting angiogenesis in mammals by administering to mammals such antibodies or Fab or F(ab').sub.2 fragments thereof so as to inhibit angiogenic activity. In addition, this invention relates to pharmaceutical compositions comprising therapeutically effective amounts of antibody that are immunologically reactive with angiogenin and which can be administered to inhibit angiogenesis.
    Type: Grant
    Filed: January 24, 1995
    Date of Patent: May 28, 1996
    Assignee: President and Fellows of Harvard College
    Inventors: James W. Fett, Bert L. Vallee, Edward M. Alderman
  • Method of isolating tumor-secreted products using a novel protein-free medium
    Patent number: 4879222
    Abstract: A medium for the maintenance of mammalian anchorage-dependent colonic adenocarcinoma cells comprising a solution of an effective maintenance amount of buffered salts, L-glutamine and glucose, which is devoid of exogenous protein. The medium further includes a solution containing amino acids.
    Type: Grant
    Filed: August 28, 1986
    Date of Patent: November 7, 1989
    Assignee: President and Fellows of Harvard College
    Inventors: Edward M. Alderman, James W. Fett, Bert L. Vallee
  • Antibodies to angiogenin: immunotherapeutic agents
    Patent number: 4853219
    Abstract: This invention relates to the production of antibodies to angiogenin or to fragments thereof and to methods of inhibiting angiogenesis in mammals by administering to mammals such antibodies or Fab fragments thereof so as to inhibit angiogenic activity. In addition, this invention relates to pharmaceutical compositions comprising therapeutically effective amounts of antibody that are immunologically reactive with angiogenin and which can be administered to inhibit angiogenesis.
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: August 1, 1989
    Assignee: President and Fellows of Harvard College
    Inventors: Edward M. Alderman, James W. Fett, Bert L. Vallee