Patents by Inventor Edward M. Croze

Edward M. Croze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel interferon for the treatment of multiple sclerosis
    Publication number: 20020025304
    Abstract: This invention relates to novel nucleic acids and polypeptide sequences, which code for an interferon-beta-2 (“IFN-&bgr;2”). A pharmaceutical composition, which comprises a pharmaceutically acceptable excipient and a therapeutically effective amount of a human IFN-&bgr;2 polypeptide, biologically-active fragment thereof, or biologically-active derivative thereof, is useful in treating multiple sclerosis in humans.
    Type: Application
    Filed: November 13, 2001
    Publication date: February 28, 2002
    Inventors: Edward M. Croze, Daryl Faulds, T. Charis Wagner
  • Monoclonal antibodies which bind (E)-5- (2-bromovinyl)-arabinofuranosyluracil and diagnostic methods based thereon
    Patent number: 5352584
    Abstract: Monoclonal antibodies which bind (E)-5-(2-bromovinyl)-arabinofuranosyluracil and/or immunologically related compounds, hybrid cell lines which produce these monoclonal antibodies, and immunoassay methods for detecting (E)-5-(2-bromovinyl)-arabinofuranosyluracil and/or immunologically related compounds using these monoclonal antibodies.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: October 4, 1994
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Edward M. Croze, Jan-I Tu, Marc D. Ogan
  • Method for purification of monoclonal antibodies
    Patent number: 5151504
    Abstract: An improved method for the purification of monoclonal antibodies using Protein G, whereby the monoclonal antibodies are eluted from the Protein G at alkaline pH.
    Type: Grant
    Filed: March 26, 1990
    Date of Patent: September 29, 1992
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Edward M. Croze
  • Monoclonal antibodies which bind thromboxane A2 receptor antagonists and diagnostic methods based thereon
    Patent number: 5141865
    Abstract: Monoclonal antibodies which bind thromboxane A2 receptor antagonists, hybrid cell lines which produce these monoclonal antibodies, and immunoassay methods for detecting thromboxane A2 receptor antagonists using these monoclonal antibodies.
    Type: Grant
    Filed: November 17, 1989
    Date of Patent: August 25, 1992
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Edward M. Croze, Jan-I Tu