Abstract: A cone-based polarizer includes a beam splitter including a front side (FS) and a back side (BS) part for receiving a first and a second beam portion, respectively. The FS part includes two prisms including parallel first and second FS hypotenuses, and the BS part includes two prisms including parallel first and second BS hypotenuses. A first TIR cone is on top and a second TIR cone is on a bottom of the beam splitter. The first and second TIR cones are aligned to have an essentially common cone axis direction and are configured to add a structured polarization upon retroreflecting. The first and second FS hypotenuses have a FS TIR interface in-between and are angled at about 45 degrees relative to the cone axis direction. The first and second BS hypotenuses have a BS TIR interface in-between and are angled at about 90 degrees relative to the FS hypotenuses.

Abstract: A device and method for delivering a drug from inside a body lumen to tissue surrounding the body lumen. An endoluminal drug delivery device includes a dual-lumen catheter for housing a guidewire and a needle connectable to a drug source. The guidewire exits the catheter through an opening at the distal end, and the needle exits the catheter through an exit port in the outer wall of the catheter. A distal portion of the catheter has a single lumen and includes a taper, allowing the distal tip to act as a dilator. The device optionally includes a catheter lumen splitter and/or a handpiece assembly. A method of delivering fluid to tissue surrounding a body lumen includes inserting a guidewire into the body lumen, tracking the device over the guidewire, deploying the needle through the exit port to the tissue, delivering fluid, and retracting the needle into the catheter.

Abstract: A laser rod assembly includes a first and second laser rod embedded in a cladding material. The assembly has a first end and a second end. The laser rods generate laser light at ?laser (?laser light) when pumped by pump power at ?pump. A reflecting outer surface at ?pump is on or over a majority of an outer surface of the cladding material. Fold optic(s) on the second end provides optical coupling between the laser rods. An optical resonator includes a highly reflecting (HR) mirror at ?laser over an end of the first laser rod on the first end and an output coupler over an end of the second laser rod also on the first end.

Abstract: A device and method for delivering a drug from inside a body lumen to tissue surrounding the body lumen. An endoluminal drug delivery device includes a dual-lumen catheter for housing a guidewire and a needle connectable to a drug source. The guidewire exits the catheter through an opening at the distal end, and the needle exits the catheter through an exit port in the outer wall of the catheter. A distal portion of the catheter has a single lumen and includes a taper, allowing the distal tip to act as a dilator. The device optionally includes a catheter lumen splitter and/or a handpiece assembly. A method of delivering fluid to tissue surrounding a body lumen includes inserting a guidewire into the body lumen, tracking the device over the guidewire, deploying the needle through the exit port to the tissue, delivering fluid, and retracting the needle into the catheter.

Abstract: A vein removal device includes a housing, a blade element disposed at least partially within the housing, and a hook element disposed at least partially within the housing. A cutting edge of the blade element is selectively exposed for making an incision in a patient. The blade element is disposed at one end of the housing and the hook element may be disposed at an opposite end of the housing. The blade element may be selectively exposed via actuation of a first user input that imparts a movement of the blade element relative to the housing and towards an extended position where the cutting edge of the blade element is exposed. The blade element may be biased toward the extended position via a biasing element, which may urge the blade element toward the extended position responsive to actuation of the first user input.

Abstract: A vein removal device includes a housing, a blade element disposed at least partially within the housing, and a hook element disposed at least partially within the housing. A cutting edge of the blade element is selectively exposed for making an incision in a patient. The blade element is disposed at one end of the housing and the hook element may be disposed at an opposite end of the housing. The blade element may be selectively exposed via actuation of a first user input that imparts a movement of the blade element relative to the housing and towards an extended position where the cutting edge of the blade element is exposed. The blade element may be biased toward the extended position via a biasing element, which may urge the blade element toward the extended position responsive to actuation of the first user input.

Abstract: Systems and methods treat superficial venous malformations, such as spider veins. The systems and methods distribute a reactive agent, e.g., a light-reactive agent such as talaporfin sodium or verteporfin, at or near an inner wall of a vein. The systems and methods activate the reactive agent by applying energy, e.g. non-thermal light energy at a wavelength that activates the reactive agent to cause localized injury to the inner wall of the vein.