Abstract: Improved compositions and methods useful in the treatment and prevention of impulsive, compulsive, reward seeking, and other addictive behaviors, including applications involving the behavioral/cognitive process of assigning importance, maintaining attention, and assessing salience. The composition includes Vitex agnus-castus (Chastetree berry) extract in an effective amount for supporting and promoting a healthy lifestyle free from addictive behavior or for preventing or treating addictive behavior. Huperzine and/or 5-HTP (5-hydroxytryptophan) may also be included. The composition may also include ingredients to address nutritional deficiencies in the addict, and nutrients depleted during the withdrawal of any reinforcer that is the object of the addiction.

Abstract: A combination of chemical agents reduces reductive stress by limiting the accumulation of high-energy electrons potentially available to the electron transport chain. A method of metabolic uncoupling therapy comprises: analyzing a specific physiologic process involving reductive stress; identifying a plurality of MUT agents that modulate metabolic pathways by influencing electron flux; and formulating a combination of MUT agents that limits the accumulation of high-energy electrons potentially available to the electron transport chain.

Abstract: Improved delivery systems and delivery methods for supporting and promoting healthy sexual function, for preventing sexual dysfunction, or for treatment of sexual dysfunction. A compositions including one or more cGMP-specific PDE5 inhibitors and/or dopaminergic agonists is administered in the form of a breath-care strip, mint or lozenge, or a food or beverage product. The cGMP-specific PDE5 inhibitor comprises an ingredient selected from the group consisting of sophoflavescenol, vardenafil, tadalafil, and sildenafil. The dopaminergic agonist comprises apomorphine. Vitex agnus-castus extract, and one or more of lipoic acid, L-Arginine, folic acid, trimethylglycine, policosanol, carnitine, biotin, and acetyl L-Carnitine may also be included in the delivery vehicle.

Abstract: Improved nutraceutical compositions and methods for supporting and promoting healthy sexual function, for preventing sexual dysfunction, or for treatment of sexual dysfunction. The compositions include a portion of the plant Sophora flavescens or an extract of the plant Sophora flavescens, such as sophoflavescenol. The compositions also include Vitex agnus-castus extract, and one or more of lipoic acid, L-Arginine, folic acid, trimethylglycine, policosanol, carnitine, biotin, and acetyl L-Carnitine and anti-oxidants.

Abstract: Improved compositions and methods useful in the treatment and prevention of impulsive, compulsive, reward seeking, and other addictive behaviors, including applications involving the behavioral/cognitive process of assigning importance, maintaining attention, and assessing salience. The composition includes Vitex agnus-castus (Chastetree berry) extract in an effective amount for supporting and promoting a healthy lifestyle free from addictive behavior or for preventing or treating addictive behavior. Huperzine and/or 5-HTP (5-hydroxytryptophan) may also be included. The composition may also include ingredients to address nutritional deficiencies in the addict, and nutrients depleted during the withdrawal of any reinforcer that is the object of the addiction.

Abstract: Improved compositions and methods are useful in the treatment and prevention of impulsive, compulsive, reward-seeking, and other addictive behaviors, including applications involving the behavioral/cognitive process of assigning importance, maintaining attention, and assessing salience. The composition includes Vitex agnus-castus (Chastetree berry) extract in an effective amount for supporting and promoting a healthy lifestyle free from addictive behavior or for preventing or treating addictive behavior. The composition also includes garcinia cambogia, aspartic acid, pyruvate, EPA (eicosapentanoic acid), biotin, L-carnitine, and chromium polynicotinate.

Abstract: A mental agility composition is composed of at least one agent which promotes synthesis of ATP and/or creatine phosphate in the body; at least one antioxidant for scavenging free radicals in at least one pathway in the body; at least one agent for normalizing or maintaining membrane function and structure in the body; at least one agent for normalizing or maintaining normal neurotransmitter function in the body; at least one agent for down-regulating cortisol action; and at least one agent for suppressing activation of apoptotic pathways in the body.

Abstract: Improved nutraceutical compositions and methods for maintaining healthy calcium metabolism and maintenance of muscle mass. The compositions include a first component selected from the group consisting of a citrate anion, a bicarbonate anion and an acetate anion; a second component selected from the group consisting of a potassium cation, a magnesium cation, a calcium cation, and a sodium cation; and a third component selected from the group consisting of resveratrol, green tea extract, tumeric, basil, sage, thyme, ginger or ginger extract, oregano or oregano extract, rosemary or rosemary extract, hypericum perforatum, glycyrrhiza glabra, plantago lanceolata, quercetin, glycyrrhiza glabra, and gingko biloba. The compositions may be administered conventionally in tablets or capsules, as a dietary supplement, or be delivered in a food additive, food or beverage product, functional food, medical food, botanical drug, over-the-counter (OTC) drug, or any other category of product for human or animal consumption.

Abstract: A composition and method for therapeutic treatment of undesirable neurophysiologic conditions, such as those associated with menopause, the peri-menstrual period, mental conditions such as mood disorders, hyperactivity, impulsiveness, difficulty concentrating, chronic pain conditions, and including neurodegenerative disorders such as age-associated or acoustic-related hearing loss, central, peripheral or autonomic neuropathies and for maintenance of neurophysiologic health, the composition comprising an effective amount of: three agents selected from the group consisting of vinpocetine, huperzine A, magnesium, theanine, pyro-glutamic acid, dextromethorphan, and Vitex agnus-castus fruit; one agent selected from the group consisting of thiamin, niacin, pyridoxine, vanadium, and acetaminophen; and three agents selected from the group consisting of valerian spp, passiflora spp, magnolia spp, scutellaria spp, taurine, melatonin, GABA and black cohosh.

Abstract: An orally or parenterally administered composition for reducing the storage of lipids in a human, the composition comprising: an effective amount of hydroxycitric acid; an effective amount of carnitine; an effective amount of biotin; an effective amount of one or more gluconeogenic substrates selected from the group consisting of: aspartate, lactate, glycerol, and a gluconeogenic amino acid or alphaketo analogue thereof; an effective amount of eicosapentanoic acid; and an effective amount of one or more ingredients selected from the group consisting of: medium chain triglycerides (MCT) with fatty acid backbones containing 6 to 14 carbon atoms or their individual fatty acid analogues or metabolic precursors, sesame seeds or derivative products, sesamin and/or its epimer episesamin, caffeine, forskolin, 7-keto dehydroepiandrosterone (7-keto DHEA), green tea extract containing epigallocatechingallate (EGCG), capsaicum, and 5-hydroxytryptophan (5-HTP).

Abstract: A food, beverage, condiment, spice or salad dressing designed to enhance the human metabolism includes a food, beverage, condiment, spice, or salad dressing base and a weight loss supplement, brain and nerve function enhancement supplement, cholesterol blocker supplement and cholesterol level improvement supplement, liver enhancement supplement, cardiac supplement, vascular supplement, anti-aging supplement, bone supplement, prostrate health enhancement supplement, joint health supplement, fetus developmental (prenatal) and/or a postnatal breast milk enhancement supplement, eye health enhancement supplement, or enhanced physical performance supplement. The supplement is present in an amount in excess of the amount naturally present in the food, beverage, condiment, spice or salad dressing base.