Patents by Inventor Edward Merle Johnson, II

Edward Merle Johnson, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings
    Patent number: 9133141
    Abstract: The present invention provides cysteine and cystine bioisosteres for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing such bioisosteres and methods of using the bioisosteres for treatment of schizophrenia and drug addiction.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: September 15, 2015
    Assignees: Marquette University, UWM Research Foundation, Inc.
    Inventors: James M. Cook, David A. Baker, Edward Merle Johnson, II, Wenyuan Yin, Ranjit Singh Verma
  • Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
    Patent number: 8962692
    Abstract: The present invention discloses cysteine prodrugs having the general formula: cystine dimers of the cysteine prodrugs having the general formula: protected cysteine analogs having the general formula: and dimers of the protected cysteine analogs having the general formula: The invention further encompasses pharmaceutical compositions containing the disclosed prodrugs, dimers, and analogs, and methods of using such compounds for treatment of schizophrenia and drug addiction.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: February 24, 2015
    Assignees: Marquette University, UWM Research Foundation, Inc.
    Inventors: James M. Cook, David A. Baker, Wenyuan Yin, Edward Merle Johnson, II
  • CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS
    Publication number: 20140155440
    Abstract: The present invention provides cysteine and cystine bioisosteres for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing such bioisosteres and methods of using the bioisosteres for treatment of schizophrenia and drug addiction.
    Type: Application
    Filed: January 7, 2014
    Publication date: June 5, 2014
    Applicants: MARQUETTE UNIVERSITY, UWM RESEARCH FOUNDATION, INC.
    Inventors: James M. Cook, David A. Baker, Edward Merle Johnson, II, Wenyuan Yin, Ranjit Singh Verma
  • Cysteine prodrugs to treat schizophrenia and drug addiction
    Patent number: 8435997
    Abstract: The present invention provides cysteine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: May 7, 2013
    Assignees: Marquette University, UWM Research Foundation, Inc.
    Inventors: James M. Cook, Edward Merle Johnson, II, David A. Baker, Wenyuan Yin
  • CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS
    Publication number: 20120220596
    Abstract: The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction.
    Type: Application
    Filed: May 7, 2012
    Publication date: August 30, 2012
    Applicants: UWM RESEARCH FOUNDATION, INC., MARQUETTE UNIVERSITY
    Inventors: James M. Cook, David A. Baker, Wenyuan Yin, Edward Merle Johnson, II
  • Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings
    Patent number: 8173809
    Abstract: The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction. Exemplary prodrugs include the cysteine compound having the formula as well as cystine dimers thereof.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: May 8, 2012
    Assignees: Marquette University, UWM Research Foundation, Inc.
    Inventors: James M. Cook, David A. Baker, Wenyuan Yin, Edward Merle Johnson, II
  • Cysteine prodrugs to treat schizophrenia and drug addiction
    Patent number: 7829709
    Abstract: The present invention provides cysteine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: November 9, 2010
    Assignees: Marquette University, University of Wisconsin - Milwaukee
    Inventors: James M. Cook, David A. Baker, Edward Merle Johnson, II, Wenyuan Yin
  • CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS
    Publication number: 20100048587
    Abstract: The present invention provides cysteine and cystine bioisosteres for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing such bioisosteres and methods of using the bioisosteres for treatment of schizophrenia and drug addiction.
    Type: Application
    Filed: April 16, 2009
    Publication date: February 25, 2010
    Applicants: Marquette University, University of Wisconsin - Milwaukee
    Inventors: James M. Cook, David A. Baker, Wenyuan Yin, Edward Merle Johnson, II
  • CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS
    Publication number: 20090281109
    Abstract: The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and compositions for treatment of schizophrenia and drug addiction.
    Type: Application
    Filed: February 9, 2009
    Publication date: November 12, 2009
    Inventors: James M. Cook, David A. Baker, Wenyuan Yin, Edward Merle Johnson, II