Abstract: The invention provides a compound of formula (1). or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: In accordance with examples of the present disclosure, a collaborative platform provides a digital collaboration assistant that continuously monitors and analyzes shared meeting contents (e.g., voice, text chat messages, shared links and documents, presentation materials, and the like) by participants during a collaborative meeting in near real-time, periodically updates a structure summary log of the meeting contents that are deemed important during the collaborative meeting, and interacts with the participants throughout the collaborative meeting in near real-time, for example, to answer questions or provide additional information.

Abstract: A method for synchronization of translation audio data includes receiving a live audio signal corresponding to a live event having spoken words in an original language. The method also includes translating the live audio signal to a first translated language and a second translated language and producing a first translated audio signal based on the first translated language and a second translated audio signal based on the second translated language. A first segment of the first translated audio signal having a first duration and a first segment of the second translated audio signal having a second duration that is longer than the first duration. The method also includes processing the first segment of the first translated audio signal into a processed first segment having a duration equal to the second duration and transmitting the processed first segment to a first mobile computing device at the live event.

Abstract: An assembly and method thereof creates a stack of objects. The assembly has a diverted to move objects having a desired size from a first conveyor to a second conveyor. The diverted utilizes diversion plates. The second conveyor transfers the objects to an accumulator. The objects that are accumulate are squared and then moved to a raised position. A lift assembly then lifts the accumulated objects that were square and translates the objects to a queuing assembly. The process repeats to construct a stack of objects with multiple layers of objects. The created stack of objects may then be transferred to a subsequent destination for further use or processing.

Abstract: A telematics device for a barrier transfer machine with machine sensors that capture operational data of the barrier transfer machine associated with a barrier segment includes a processing element, a communication element, and a memory element. The processing element is configured to receive the captured operational data. The communication element is in communication with the processing element and is configured to wirelessly transmit a signal representative of at least a portion of the captured operational data. The memory element is in communication with the processing element and is configured to store at least a portion of the captured operational data.

Abstract: Disclosed embodiments may include a method for authenticating calls for a call center where the user can authenticate before or after starting a call to a call center using an application on a user device. The system determines what level of authentication is necessary depending on the task the user wants to accomplish during the call. The system may direct the user to provide credentials, such as a username and password, for some tasks. Other tasks may require the user to verify their financial card by taking a photo of their financial card or tapping their financial card to their device and allow the device to interact with the financial card using NFC technology. Once appropriately authenticated, the system then allows the user to make a call to the call center and also sends a signal to the call center that the user has been previously authenticated.

Abstract: A glass container comprises a glass body comprising a first region under a compressive stress extending from a surface of the glass body to a depth of compression and a second region extending from the depth of compression into a thickness of the glass body, the second region being under a tensile stress. The glass container also includes a localized compressive stress region having a localized compressive stress extending from the surface to a localized depth of compression within the body. The localized depth of compression is greater than the depth of compression of the first region. The glass container also includes a crack re-direction region extending in a predetermined propagation direction, wherein the crack re-direction region possesses a higher tensile stress than the tensile stress in the second region in a sub-region of the crack re-direction region, the sub-region extending substantially perpendicular to the predetermined propagation direction.

Abstract: Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.

Abstract: Systems and methods for purging smoke and other gasses from containers are provided. First portions of a coupling device are fixed to the containers and each define a first inner passageway. A second portion of the coupling device is configured for selective securement to any of the first portions to create a fluid passageway from an interior of the container, through the coupling device, to an ambient environment outside of the container. An airflow device may be fluidly connected to said second portion by ductwork.

Abstract: Systems and methods of obtaining a virtual representation of a physical object at point of sale are presented. In one exemplary embodiment, a POS system includes a first sensor device operable to sense an identifier unique to a physical object and a second sensor device operable to capture a digital image of the physical object during checkout by the POS system. Further, the POS system is communicatively coupled to a blockchain network that includes network nodes that are collectively configured to operate a blockchain. The unique physical object identifier is associated with a cryptographic digital asset stored on the blockchain as a code that represents the unique physical object identifier and a code that represents a reference to a virtual object obtained based on a digital image of the physical object captured by the second sensor during the checkout by the POS system.

Abstract: In one aspect of the present disclosure, a system and method are provided for pairing a network-enabled movable barrier operator with a transmitter. The method may include receiving a pairing request, retrieving a hashed version of the transmitter fixed code, verifying access authorization, and forwarding the hashed version of the transmitter fixed code to a movable barrier operator to allow the movable barrier operator to determine whether a new transmitter is authorized to control the movable barrier operator.

Abstract: A method for a robotic surgical system includes displaying a graphical user interface on a display to a user, wherein the graphical user interface includes a plurality of reconfigurable display panels, receiving a user input at one or more user input devices, wherein the user input indicates a selection of at least one software application relating to the robotic surgical system, and rendering content from the at least one selected software application among the plurality of reconfigurable display panels.

Abstract: Described embodiments relate to a chemical processing instrument configured to receive one or more sample cartridges, to process one or more corresponding fluid samples. The chemical processing instrument comprises: a reagent dispenser configured to dispense one or more fluid reagents into a reagent vessel via an open top of the reagent vessel; and a pneumatic module configured to connect to a primary pneumatic port of a primary reaction vessel and selectively adjust a pressure within the primary reaction vessel when the lid is closed to draw fluid from the reagent vessel through a primary reagent channel into the primary reaction vessel.

Abstract: In one aspect of the present disclosure, a system and method are provided for pairing a network-enabled movable barrier operator with a transmitter. The method may include receiving a pairing request, retrieving a hashed version of the transmitter fixed code, verifying access authorization, and forwarding the hashed version of the transmitter fixed code to a movable barrier operator to allow the movable barrier operator to determine whether a new transmitter is authorized to control the movable barrier operator.

Abstract: In one aspect, an in-vehicle device is provided that includes a sensor configured to detect a vehicle characteristic indicative of the vehicle being in proximity to a location associated with a movable barrier operator. The in-vehicle device includes communication circuitry to communicate an open command to the movable barrier operator that causes the movable barrier operator to open a movable barrier connected to the movable barrier operator. A memory is configured to store a vehicle arrival condition indicative of whether the vehicle arrived at the location associated with the movable barrier operator. A processor is configured to determine satisfaction of the vehicle arrival condition and, upon the vehicle arrival condition not being satisfied, cause the communication circuitry to communicate a close command to the movable barrier operator that causes the movable barrier operator to close the movable barrier.

Abstract: Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces. A spatial disposition of an incision of the cornea is generated based at least in part on the measured corneal anterior and posterior spatial dispositions and at least one corneal incision parameter. A composite image is displayed that includes an image representative of the measured corneal anterior and posterior surfaces and an image representing the corneal incision.

Abstract: A method for processing video comprises storing, at a video data buffer, an input video frame data received from a source, causing the stored video frame data to be output from the video data buffer at an output video frame rate, and varying the output video frame rate based on a comparison of an amount of video frame data stored at the video data buffer to a threshold amount of frame data. The threshold amount of frame data may be based on a target total latency between capture of the input video frame data at the source and display of the stored video frame data output from the video data buffer.

Abstract: A method for a robotic surgical system includes displaying a graphical user interface on a display to a user, wherein the graphical user interface includes a plurality of reconfigurable display panels, receiving a user input at one or more user input devices, wherein the user input indicates a selection of at least one software application relating to the robotic surgical system, and rendering content from the at least one selected software application among the plurality of reconfigurable display panels.