Abstract: A container (32) includes a sealable body including a chamber (42), at least one opening formed in the sealable body, and a vacuum sealing assembly (52) mounted to the sealable body adjacent at least one opening. The vacuum sealing assembly (52) includes a valve (60) and a mechanism (70) moveable between a first position that maintains the valve (60) in a sealing engagement with at least one opening and a second position that removes the valve (60) from the sealing engagement or exposes the valve (60) for removal from the sealing engagement.

Abstract: Described herein are devices, compositions and methods relating to the production of high basis weight, non-woven nanofiber polymer fabrics. In certain embodiments, described herein are modifications to free-surface, needle-less or nozzle-less electrospinning devices that permit the production of such high basis weight, non-woven nanofiber polymer fabrics. Also described are the fabrics themselves and the fabrics including one or more biologically active agents to be released upon contact with a biological tissue. Such fabrics can incorporate biologically active agents in various combinations that permit, for example, burst and/or sustained release kinetics of one or more, preferably two or more biologically active agents.