Abstract: An insect repellent articles, such as tubular articles and patches, wherein an exemplary patch includes: a support film having a first major surface and a second major surface; a body-contacting pressure sensitive adhesive layer disposed on the first major surface; and a reservoir layer disposed on the second major surface, wherein the reservoir layer comprises an insect repellent incorporated within a polymeric carrier, and wherein the reservoir layer forms a non-contacting surface.

Abstract: The present disclosure is directed to a method for providing a flow-able hydrogel for germinating, cultivating, transporting or displaying plants. The method generally includes at least three distinct steps: 1) dissolving a polyethylene glycol having functionalized end-groups in water to form a flow-able solution, 2) dissolving one or more activating agents within the flow-able solution such that the activating agents react with the functionalized end-groups of the polyethylene glycol to form a non-flow-able hydrogel after a set-time, 3) pouring the flow-able solution into a container prior to the set time such that the flow-able solution assumes the shape of the container and forms a non-flow-able hydrogel.

Abstract: The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.

Abstract: The present invention is directed to bioabsorbable medical devices which are introduced into the body of a subject in a first configuration and deformed in the subject's body to a second configuration. The devices generally include at least one bioabsorbable expandable device component that comprises at least one type of biodegradable polymer. In accordance with an aspect of the invention, the expandable device component is crosslinked while in an expanded configuration. The crosslinked device component is then heated to a temperature above the glass transition temperature (Tg) of the material forming the device component. Upon heating to this temperature, the device component is compressed into a contracted configuration and cooled to below the Tg of the material to maintain the contracted configuration.

Abstract: The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.

Abstract: The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.

Abstract: The present disclosure is directed to surface functionalized ceramic nanoparticles. The method for producing the surface functionalized ceramic nanoparticles generally includes at least four distinct steps: 1) synthesis of an amphiphilic surfactant having the desired surface functionality, 2) formation of mixed solvent microstructured solution with the surfactant, 3) synthesis of the desired ceramic within the microstructured solution, and 4) chemical attachment of the surfactant to the ceramic nanoparticle. The composition of the surface functionalized nanoparticle comprises a lipophilic component, a hydrophilic component, a chelating agent and a ceramic forming component.

Abstract: Fluoropolymers having a —CF adjacent to a —CH which are subsequently dehydrofluorinated to create a —C?C— can be used as controlled release carriers for therapeutic agent(s) by covalently conjugating the therapeutic agent(s) to the fluoropolymer at the —C?C—.

Abstract: The present invention is directed to bioabsorbable medical devices which are introduced into the body of a subject in a first configuration and deformed in the subject's body to a second configuration. The devices generally include at least one bioabsorbable expandable device component that comprises at least one type of biodegradable polymer. In accordance with an aspect of the invention, the expandable device component is crosslinked while in an expanded configuration. The crosslinked device component is then heated to a temperature above the glass transition temperature (Tg) of the material forming the device component. Upon heating to this temperature, the device component is compressed into a contracted configuration and cooled to below the Tg of the material to maintain the contracted configuration.

Abstract: An endovascular stent comprising an expandable framework including a plurality of interconnected segments, and a plurality of entangled cylindrical micelles disposed on the expandable framework. Each of the plurality of cylindrical micelles may be loaded with a therapeutic agent.

Abstract: The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provided a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.

Abstract: The present invention provides medical devices comprising nanocomposite materials. By utilizing nanocomposites in the production thereof, the inventive medical devices can be produced with various advantageous properties. Methods of producing the inventive medical devices are also provided. Inasmuch as the inventive devices are expected to provide certain advantages in their use, there is also provide a method of medical care including methods of treatment or diagnosis, wherein the inventive devices are brought into therapeutic contact with a body to be treated or diagnosed thereby.

Abstract: Fluoropolymers having a —CF adjacent to a —CH which are subsequently dehydrofluorinated to create a —C?C— can be used as controlled release carriers for therapeutic agent(s) by covalently conjugating the therapeutic agent(s) to the fluoropolymer at the —C?C—.

Abstract: A substantially tubular member comprises a body. The body is constructed from a first material and has an external surface. At least a portion of the external surface has a predetermined pattern of a second material deposited thereon. The predetermined pattern of the second material is deposited on the at least a portion of the external surface by one or more printing processes such as solution coating, spray coating, thermal printing, piezo jet printing, contact printing and any combination thereof.

Abstract: An endovascular stent comprising an expandable framework including a plurality of interconnected segments, and a plurality of entangled cylindrical micelles disposed on the expandable framework. Each of the plurality of cylindrical micelles may be loaded with a therapeutic agent.

Abstract: A medical tubing is disclosed which includes a first material extending between proximal and distal ends of the tubing and which defines a lumen of the tubing. The tubing also includes a second material extending between at least portion of the distance between the proximal and distal ends of the tubing and that is embedded in the first material. The second material is fractured. The first material is flexible and the second material is relatively rigid and brittle and the two materials combined to provide a medical tubing that exhibits strain softening behavior.

Abstract: Coated medical devices and methods for coating such devices are disclosed. The invention is directed to the use of an anti-adhesion agent in a coating for a medical device. More particularly, the invention is directed to a medical device comprising an anti-adhesion agent that prevents the self-adhesion of different portions of a coating disposed on the surface of the medical device. Additionally, this invention is directed to methods for coating such a medical device.

Abstract: A medical tubing is disclosed which includes a first material extending between proximal and distal ends of the tubing and which defines a lumen of the tubing. The tubing also includes a second material extending between at least portion of the distance between the proximal and distal ends of the tubing and that is embedded in the first material. The second material is fractured. The first material is flexible and the second material is relatively rigid and brittle and the two materials combined to provide a medical tubing that exhibits strain softening behavior.

Abstract: A medical device comprising a first substrate, a second substrate and a powder coated tie layer between the first and second substrates resulting in a multilayer construction.

Abstract: A medical device comprising a first substrate, a second substrate and a powder coated tie layer between the first and second substrates resulting in a multilayer construction.