Abstract: When rendering a region of a three-dimensional object represented by a base set of polygon vertices in a graphics processing pipeline, a first processing stage uses meta-information representative of the surface relief of the region of the three-dimensional object to determine whether to generate a set of additional polygon vertices over the region of the three-dimensional object, and generates the additional set of polygon vertices (when this is deemed necessary). A second processing stage then uses information representative of the surface relief of the region of the three-dimensional object to modify the positions of one or more of the polygon vertices, before the vertices are assembled into primitives that are then rasterised and rendered.

Abstract: When rendering a region of a three-dimensional object represented by a base set of polygon vertices in a graphics processing pipeline, a first processing stage uses meta-information representative of the surface relief of the region of the three-dimensional object to determine whether to generate a set of additional polygon vertices over the region of the three-dimensional object, and generates the additional set of polygon vertices (when this is deemed necessary). A second processing stage then uses information representative of the surface relief of the region of the three-dimensional object to modify the positions of one or more of the polygon vertices, before the vertices are assembled into primitives that are then rasterised and rendered.

Abstract: A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.

Abstract: In a graphics processing system, when a fragment reaches a texturing stage, it is determined whether the texture to be applied is a static or dynamic texture. If it is determined that the required texels relate to a dynamic texture, then the system first tries to fetch those texels from a dynamic texture memory. If it is found that the texels are not available in the dynamic texture memory, then the relevant texels are generated in an “on-demand” fashion and stored in the dynamic texture memory so that they can be applied to the fragment.

Abstract: Disclosed herein are methods and devices for detection of bacterial HAI. Disclosed methods may be utilized for continuous in vivo monitoring of a potential bacterial infection site and may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of infection. Disclosed methods include utilization of recombinant bacteriophage to deliver to pathogenic bacteria a translatable genetic sequence encoding an optically detectable marker or an enzyme capable of producing an optically detectable marker. Upon detection of the optical signal produced by the marker, medical personnel may be alerted to the presence of pathogenic bacteria at the site of inquiry. Any bacterial causative agent of HAI may be detected according to disclosed methods.

Abstract: A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential bacterial infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of a hospital acquired infection, thereby providing for earlier intervention. Disclosed methods utilize optical fibers to deliver an excitation signal to an area in which pathogenic bacteria may exist. In the presence of the excitation signal, bacterial pathogens may autofluoresce with a unique spectral signature. Upon generation of a fluorescent emission, an optically detectable emission signal may be transmitted to a detection/analysis device. Analysis of the characteristics of the emission signal produced in response to the excitation signal may be used to determine the presence or concentration of pathogens at the site of inquiry, following which real time information may be transmitted to medical personnel via a wireless transmission system.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site and may be utilized to alert patients and/or health care providers to changes in the local environment due to the presence of a pathogen at an early stage of infection. Disclosed methods utilize ion sensitive field effect transistors (ISFETs) to detect changes in ionic concentration at the site due to the presence of a pathogen, for instance at a surgical site. When a pathogen is present, the local ionic concentration, and hence the electrical characteristics of an ISFET may change, causing a detectable signal from the ISFET. An ISFET may be associated with a biological material such as an enzyme or a specific binding partner for an expression product of a pathogen to improve detection.

Abstract: Disclosed herein are methods and devices for detection of bacterial HAI. Disclosed methods may be utilized for continuous in vivo monitoring of a potential bacterial infection site and may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of infection. Disclosed methods include utilization of recombinant bacteriophage to deliver to pathogenic bacteria a translatable genetic sequence encoding an optically detectable marker or an enzyme capable of producing an optically detectable marker. Upon detection of the optical signal produced by the marker, medical personnel may be alerted to the presence of pathogenic bacteria at the site of inquiry. Any bacterial causative agent of HAI may be detected according to disclosed methods.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site.

Abstract: A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.

Abstract: In a graphics processing system, when a fragment reaches a texturing stage, it is determined whether the texture to be applied is a static or dynamic texture (Step 24). If it is determined that the required texels relate to a dynamic texture, then the system first tries to fetch those texels from a dynamic texture memory (Step 25). If it is found that the texels are not available in is the dynamic texture memory, then the relevant texels are generated in an “on-demand” fashion (Step 27) and stored in the dynamic texture memory (Step 28), so that they can be applied to the fragment.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential bacterial infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of a hospital acquired infection, thereby providing for earlier intervention and improved recovery rates from bacterial infection. Disclosed methods utilize optical fibers to deliver an excitation signal to an area in which pathogenic bacteria may exist. In the presence of the excitation signal, bacterial pathogens may autofluoresce with a unique spectral signature. Upon generation of a fluorescent emission, an optically detectable emission signal may be transmitted to a detection/analysis device.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of a hospital acquired infection, thereby providing for earlier intervention and improved recovery rates from bacterial infection. Disclosed methods utilize implantable devices for location at an in vivo site. The implantable device is held in conjunction with an optical fiber that detects and transmits an optically detectable signal generated in the presence of a pathogen. Upon generation of the emission, the optically detectable emission signal may be transmitted to a portable detection/analysis device. Analysis of the characteristics of the emission signal produced may be used to determine the presence or concentration of pathogens at the site of inquiry, following which real time information may be transmitted to medical personnel, for instance via a wireless transmission system.

Abstract: A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.

Abstract: A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.