Patents by Inventor Edward R. Truitt, III

Edward R. Truitt, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of PRG4 to improve dynamic visual acuity and higher order aberrations
    Patent number: 11666529
    Abstract: Disclosed are methods involving the therapeutic use of human PRG4 (lubricin) protein, to improve vision, to reduce aberrations such as impaired night vision, halos, and glare, to improve the stability of the tear film, and to homogenize the refractive index of the surface of the eye.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: June 6, 2023
    Assignee: Lubris LLC
    Inventors: Benjamin D. Sullivan, Edward R. Truitt, III
  • Oral care compositions and methods
    Patent number: 11213566
    Abstract: Provided herein is a pharmaceutical or oral care product for treating or preventing oral diseases that is prepared with proteoglycan 4 (PRG4) as an active ingredient, the preparing method thereof and the use thereof in manufacturing medicaments or oral care products for treating or preventing oral diseases and maintenance of oral health. PRG4 may have efficacy in maintaining oral health and treating or preventing oral disease. This secreted glycoprotein, which is also called lubricin and superficial zone protein, is known to protect against frictional forces, cell adhesion and protein deposition.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: January 4, 2022
    Assignee: LUBRIS LLC
    Inventors: Edward R. Truitt, III, Benjamin Sullivan, Nicholas Tennison
  • USE OF PRG4 TO IMPROVE DYNAMIC VISUAL ACUITY AND HIGHER ORDER ABERRATIONS
    Publication number: 20180140546
    Abstract: Disclosed are methods involving the therapeutic use of human PRG4 (lubricin) protein, to improve vision, to reduce aberrations such as impaired night vision, halos, and glare, to improve the stability of the tear film, and to homogenize the refractive index of the surface of the eye.
    Type: Application
    Filed: May 19, 2016
    Publication date: May 24, 2018
    Inventors: Benjamin D. Sullivan, Edward R. Truitt, III
  • TOPICAL USE OF PRG4 FOR TREATMENT OF ALLERGY AND SYMPTOMS OF INFLAMMATION
    Publication number: 20170312335
    Abstract: Disclosed are methods involving the therapeutic use of human PRG4 (PRG4) protein, to ameliorate the symptoms associated with allergies and/or respiratory infections.
    Type: Application
    Filed: December 30, 2016
    Publication date: November 2, 2017
    Inventors: Edward R. Truitt, III, Benjamin Sullivan
  • PRG4 treatment for interstitial cystitis
    Patent number: 9107885
    Abstract: The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis in vivo. In a preferred embodiment, the present invention relates to treatment formulations and methods for reducing interstitial cystitis in patients via administration of a therapeutically effective concentration of PRG4.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: August 18, 2015
    Assignee: LUBRIS LLC
    Inventors: Benjamin David Sullivan, Edward R. Truitt, III
  • Therapeutic modulation of vaginal epithelium boundary lubrication
    Patent number: 8980840
    Abstract: The present invention relates to the management of vaginal health. In particular, the present invention relates to pharmaceutical compositions, and methods of use thereof, for treating diseases associated with compromised boundary lubrication at the vaginal epithelium.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: March 17, 2015
    Assignees: Schepens Eye Research Institute, Lubris LLC
    Inventors: Edward R. Truitt, III, Benjamin Sullivan, David Sullivan
  • ORAL CARE COMPOSITIONS AND METHODS
    Publication number: 20130039865
    Abstract: Provided herein is a pharmaceutical or oral care product for treating or preventing oral diseases that is prepared with proteoglycan 4 (PRG4) as an active ingredient, the preparing method thereof and the use thereof in manufacturing medicaments or oral care products for treating or preventing oral diseases and maintenance of oral health. PRG4 may have efficacy in maintaining oral health and treating or preventing oral disease. This secreted glycoprotein, which is also called lubricin and superficial zone protein, is known to protect against frictional forces, cell adhesion and protein deposition.
    Type: Application
    Filed: January 19, 2011
    Publication date: February 14, 2013
    Inventors: Edward R. Truitt, III, Benjamin Sullivan, Nicholas Tennison
  • PRG4 TREATMENT FOR INTERSTITIAL CYSTITIS
    Publication number: 20120321693
    Abstract: The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis in vivo. In a preferred embodiment, the present invention relates to treatment formulations and methods for reducing interstitial cystitis in patients via administration of a therapeutically effective concentration of PRG4.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 20, 2012
    Inventors: Benjamin David Sullivan, Edward R. Truitt, III
  • THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION
    Publication number: 20120052077
    Abstract: The present invention relates to the management of vaginal health. In particular, the present invention relates to pharmaceutical compositions, and methods of use thereof, for treating diseases associated with compromised boundary lubrication at the vaginal epithelium.
    Type: Application
    Filed: January 13, 2010
    Publication date: March 1, 2012
    Inventors: Edward R. Truitt, III, Benjamin Sullivan, David Sullivan