Abstract: Methods and corresponding uses are provided for treating disease in a patient, involving the use of sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] so as to ameliorate drug resistance, including resistance to proteasome inhibitors and immunomodulatory imide drugs. The disease may for example be relapsing/refractory multiple myeloma.

Abstract: An autonomous driving system comprising: an image encoder configured to receive video input data, said video input data comprising a plurality of time-varying image frames, wherein the image encoder is further configured to encode the image frames as a sequence of input tokens; a pre-trained world model having a set of pre-trained world model weights, the world model being configured to receive the sequence of input tokens and to generate therefrom a world state based on said sequence, wherein the world state comprises an implicit representation of candidate future events; a driving decoder configured to receive the world state from the world model and to generate in a single forward pass a driving plan based on the implicit representation of candidate future events.

Abstract: An optical fiber array assembly for high power applications includes a support structure, an optical fiber array, a plurality of end caps and a fluid conduit arrangement. The optical fiber array extends through the support structure and has a plurality of optical fibers extending in a common longitudinal direction. The plurality of end caps is arranged such that each of the end caps is attached to an end portion of one of the optical fibers. The fluidic conduit arrangement has one or more conduits extending through the support structure. The one or more conduits are configured to support a flow of fluid therein to remove heat arising from optical energy back reflected from the end caps that enters the support structure.

Abstract: Edible compositions are provided and comprise a soluble mineral component and/or a phosphate component in amounts effective for use as an oral medicament. The soluble mineral component comprises one or more minerals selected from the group consisting of zinc, manganese, tin, copper, and mixtures thereof. The edible compositions are advantageously companion animal chews, treats or supplements. Further disclosed are methods of making the chews, treats or supplements as are methods of treating conditions of the oral cavity.

Abstract: A plurality of video items comprising a first subset of video items and a second subset of video items are received at a client device. A graphical user interface comprising a scrollable area displaying the first subset of video items and a focus area displaying one of the plurality of video items is presented. Preview of video items of the second subset of video items is provided in or adjacent to the focus area in the GUI on the client device prior to receiving a scrolling request of a user of the client device to cause the second subset of video items to become visible in the first scrollable area. Video items of the second subset of video items are presented in the preview as GUI elements each comprising an icon representing a corresponding video item.

Abstract: A plurality of video items comprising a first subset of video items and a second subset of video items are received at a client device. A graphical user interface comprising a scrollable area to present the plurality of video items and a focus area to present one of the plurality of video items is presented. Video items of the second subset of video items are presented in or adjacent to the focus area when the first subset of video items is visible in the scrollable area and prior to the second subset of video items becoming visible in the scrollable area, and a size of the video items from the second subset of video items presented in or adjacent to the focus area is smaller than a size of video items of the first subset of video items presented in the scrollable area.

Abstract: Devices, systems, and methods are directed to the use of vapor phase change in binder jetting processes for forming three-dimensional objects. In general, a vapor of a first fluid may be directed to a layer of a powder spread across a build volume. The vapor may condense to reduce mobility of the particles of the powder of the layer. For example, the condensing vapor may reduce the likelihood of particle ejection from the layer and, thus, may reduce the likelihood of clogging or otherwise degrading a printhead used to jet a second fluid (e.g., a binder) to the layer. Further, or instead, the condensing vapor may increase the density of the powder in the layer which, when repeated over a plurality of layers forming a three-dimensional object, may reduce the likelihood of slumping of the part during sintering.

Abstract: A method of transferring at least one subterranean core sample from a retrieval vessel to a testing vessel can include removing at least one pressure barrier on the retrieval vessel using a linear actuator while maintaining a sampling pressure on the at least one subterranean core sample at which the at least one subterranean core sample is taken from a subterranean formation. The method can also include pressurizing the testing vessel to the sampling pressure using the linear actuator, and transferring the at least one subterranean core sample from the retrieval vessel to the testing vessel. The method can further include sealing the testing vessel with the at least one subterranean core sample at the sampling pressure, where the testing vessel allows the at least one subterranean core sample to be tested while the at least one subterranean core sample is maintained at the sampling pressure.

Abstract: Systems and methods that may be used to implement overlapping data caching for object application program interfaces (APIs). A unique identifier may be assigned to each sub-component of an object API request. The unique identifiers may be used to determine if sub-components of one object API request overlaps with a sub-component of a prior different request such that a data response for the prior different request can be retrieved from the cache and used as part of the data response for the current object API request.

Abstract: The present application relates to the administration of plasma, fractions thereof, or mixtures thereof to humans or animals to treat or otherwise improve cognitive impairment disorders, including dementia (e.g., vascular dementia, dementia with Lewy bodies, dementia resulting from Alzheimer's disease, dementia resulting from Parkinson's disease, frontotemporal dementia, and dementia resulting from normal pressure hydrocephalus in humans, and cognitive dysfunction syndrome in companion animals), concussion, and traumatic brain injury.

Abstract: Devices, systems, and methods are directed to the use of vapor phase change in binder jetting processes for forming three-dimensional objects. In general, a vapor of a first fluid may be directed to a layer of a powder spread across a build volume. The vapor may condense to reduce mobility of the particles of the powder of the layer. For example, the condensing vapor may reduce the likelihood of particle ejection from the layer and, thus, may reduce the likelihood of clogging or otherwise degrading a printhead used to jet a second fluid (e.g., a binder) to the layer. Further, or instead, the condensing vapor may increase the density of the powder in the layer which, when repeated over a plurality of layers forming a three-dimensional object, may reduce the likelihood of slumping of the part during sintering.

Abstract: An improved lunging tool utilized to train animals, such as horses. The lunging tool includes a stiffening component inserted into an internal pocket of the body. The lunging tool is configured to attach to a harness or halter on one end and a lunging line or rope on the other end to enable a trainer to lead the animal by both pushing and pulling on the animal. The length of the stiffening component of the improved lunging tool prevents entanglement with the animal's legs if the trainer drops the improved lunging tool.

Abstract: Devices, systems, and methods are directed to the use of vapor phase change in binder jetting processes for forming three-dimensional objects. In general, a vapor of a first fluid may be directed to a layer of a powder spread across a build volume. The vapor may condense to reduce mobility of the particles of the powder of the layer. For example, the condensing vapor may reduce the likelihood of particle ejection from the layer and, thus, may reduce the likelihood of clogging or otherwise degrading a printhead used to jet a second fluid (e.g., a binder) to the layer. Further, or instead, the condensing vapor may increase the density of the powder in the layer which, when repeated over a plurality of layers forming a three-dimensional object, may reduce the likelihood of slumping of the part during sintering.

Abstract: A medially stabilized surge suppressor has longitudinal members joined together at opposite ends of the members and a medial disk supporting the members. The longitudinal members are fastened to the medial disks by tabs that pass through elongate slots located in the longitudinal members. The longitudinal members each include a number of flow orifices that enable fluid through the flow orifices as well as between the longitudinal members. The end portions of the longitudinal members are joined at each of first and second junctions by a pin and a washer forming a non-rotable connection between them.

Abstract: Systems and methods that may be used to implement overlapping data caching for object application program interfaces (APIs). A unique identifier may be assigned to each sub-component of an object API request. The unique identifiers may be used to determine if sub-components of one object API request overlaps with a sub-component of a prior different request such that a data response for the prior different request can be retrieved from the cache and used as part of the data response for the current object API request.

Abstract: An exemplary embodiment includes a system for an information visualization engine designed to dynamically organize, via associative clustered tiling and tessellation, and then present instantly addressable content via any electronic user interface, but especially via mobile devices such as touch screen cellular phones, and tablets.

Abstract: The present invention relates to a modular way to build a rolling chassis using composite materials without custom forming, and yielding appropriate weight distribution (centre of gravity) and torsional and bending rigidity.

Abstract: A computing device detects a trigger or context associated with exchanging, using a body area network (BAN), body area network services with another device. The BAN services can include a discovery service to allow the computing device to connect to a network. Responsive to detecting the trigger or context, one or more body area networks are discovered and the other device is discovered. If the computing device and the other device are new to each other, the computing device is authenticated to the body area network one or more body area network services can be exchanged. If the devices are not new to each other, body area network services can be exchanged using the other device.

Abstract: Devices, systems, and methods are directed to the use of vapor phase change in binder jetting processes for forming three-dimensional objects. In general, a vapor of a first fluid may be directed to a layer of a powder spread across a build volume. The vapor may condense to reduce mobility of the particles of the powder of the layer. For example, the condensing vapor may reduce the likelihood of particle ejection from the layer and, thus, may reduce the likelihood of clogging or otherwise degrading a printhead used to jet a second fluid (e.g., a binder) to the layer. Further, or instead, the condensing vapor may increase the density of the powder in the layer which, when repeated over a plurality of layers forming a three-dimensional object, may reduce the likelihood of slumping of the part during sintering.

Abstract: A system, computer-readable medium, and a method including accessing a semantic model, the semantic model having a grammar syntax supporting a comparison of at least one of a semantic model class and an instance of a semantic model class to an incompatible value; specifying an implied property for at least one of a semantic model class and an instance of a semantic model class in the semantic model, the implied property having an associated range; adding the implied property to the semantic model, the implied property to be referenced in a validation and translation of an expression including at least one of the class and the instance of a class having the implied property specified therewith compared to an incompatible value; and generating a record of the semantic model including the implied property added thereto.