Patents by Inventor Edward Steele
Edward Steele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12202827Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: GrantFiled: August 9, 2022Date of Patent: January 21, 2025Assignee: DAMIAN PHARMA AGInventors: Christoph Schumacher, Walter Fuhrer, Ronald Edward Steele
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Publication number: 20240265026Abstract: In one embodiment, a computer system comprises one or more central processing units (CPUs) that are communicatively coupled to a system clock, one or more network interfaces, and one or more database interfaces; digital electronic main memory that is communicatively coupled to the one or more CPUs and storing one or more sequences of stored program instructions which, when executed using the one or more CPUs, cause the one or more CPUs to execute a plurality of different consumer services of a SaaS-based data analytics platform, each of the consumer services hosting an instance of a sandboxed runtime for a hermetic and deterministic programming language; user function storage that is communicatively coupled to one of the database interfaces and storing a plurality of different user functions, each of the user functions having been programmed using the programming language, each of the user functions being stored in association with a reference to a destination table of a destination database; each of the consType: ApplicationFiled: April 17, 2024Publication date: August 8, 2024Inventors: Timothée Peignier, Edward Steel
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Patent number: 12013867Abstract: In one embodiment, a computer system comprises one or more central processing units (CPUs) that are communicatively coupled to a system clock, one or more network interfaces, and one or more database interfaces; digital electronic main memory that is communicatively coupled to the one or more CPUs and storing one or more sequences of stored program instructions which, when executed using the one or more CPUs, cause the one or more CPUs to execute a plurality of different consumer services of a SaaS-based data analytics platform, each of the consumer services hosting an instance of a sandboxed runtime for a hermetic and deterministic programming language; user function storage that is communicatively coupled to one of the database interfaces and storing a plurality of different user functions, each of the user functions having been programmed using the programming language, each of the user functions being stored in association with a reference to a destination table of a destination database; each of the consType: GrantFiled: July 27, 2022Date of Patent: June 18, 2024Assignee: Treasure Data, Inc.Inventors: Timothée Peignier, Edward Steel
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Patent number: 11992479Abstract: The present invention relates to a composition for use in the treatment of a disease or disorder, wherein said disease or disorder is preferably a disease or disorder in which aldosterone overexposure contributes to the symptoms of said disease or disorder, said composition comprises a compound which is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine or a pharmaceutically acceptable salt thereof, wherein preferably said compound is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazolium[1,5-a]pyridine dihydrogen phosphate, and wherein said compound has an enantiomeric excess (ee) of the (R) form higher than or equal to 97%, and wherein said composition is administered once daily to a subject in need thereof.Type: GrantFiled: May 2, 2019Date of Patent: May 28, 2024Assignee: DAMIAN PHARMA AGInventors: Ronald Edward Steele, Christoph Schumacher
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Publication number: 20240037114Abstract: In one embodiment, a computer system comprises one or more central processing units (CPUs) that are communicatively coupled to a system clock, one or more network interfaces, and one or more database interfaces; digital electronic main memory that is communicatively coupled to the one or more CPUs and storing one or more sequences of stored program instructions which, when executed using the one or more CPUs, cause the one or more CPUs to execute a plurality of different consumer services of a SaaS-based data analytics platform, each of the consumer services hosting an instance of a sandboxed runtime for a hermetic and deterministic programming language; user function storage that is communicatively coupled to one of the database interfaces and storing a plurality of different user functions, each of the user functions having been programmed using the programming language, each of the user functions being stored in association with a reference to a destination table of a destination database; each of the consType: ApplicationFiled: July 27, 2022Publication date: February 1, 2024Inventors: Timothée Peignier, Edward Steel
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Patent number: 11447491Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: GrantFiled: August 12, 2020Date of Patent: September 20, 2022Assignee: DAMIAN PHARMA AGInventors: Christoph Schumacher, Walter Fuhrer, Ronald Edward Steele
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Patent number: 10822332Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: GrantFiled: October 26, 2017Date of Patent: November 3, 2020Assignee: DAMIAN PHARMA AGInventors: Christoph Schumacher, Walter Fuhrer, Ronald Edward Steele
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Patent number: 10745769Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with a treatment formulation and a solid particulate material in a sealed apparatus wherein the treatment formulation comprises a tanning agent or a tannery process agent. The method can comprise applying the tanning agent or tannery process agent to the animal substrate wherein at least some of the agent so applied originates from the treatment formulation. There is also disclosed an animal substrate obtained by the method. The treatment formulation can be aqueous.Type: GrantFiled: April 11, 2014Date of Patent: August 18, 2020Assignee: Xeros LimitedInventor: John Edward Steele
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Patent number: 10494590Abstract: The invention provides a cleaning formulation comprising a multiplicity of solid cleaning particles, wherein the solid cleaning particles comprise polymeric particles and at least one cleaning agent, wherein the at least one cleaning agent is immobilised on the surface of the polymeric particles. Typically the at least one cleaning agent is immobilised on the surface of the polymeric particles by means of chemical bonds, typically ionic bonds, hydrogen bonds, covalent bonds, polar bonds, or bonds formed by virtue of unequal charge distributions between polymeric particles and immobilised materials. The invention also provides a method for the cleaning of a substrate, the method comprising the treatment of the substrate with a formulation according to the invention, and a method for the preparation of the cleaning formulation of the invention which comprises treating a multiplicity of polymeric particles with at least one cleaning agent.Type: GrantFiled: July 8, 2013Date of Patent: December 3, 2019Assignee: Xeros LimitedInventors: Elizabeth Jean Abercrombie, Ana America Tellechea Lopez, John Edward Steele, Stephen Derek Jenkins
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Patent number: 10301691Abstract: A method for tanning an animal substrate comprising the steps: i) agitating the animal substrate with a chromium-free tanning agent; and ii) agitating the animal substrate with a tanning agent having an oxazolidine group; wherein at least some of the agitation is performed in the presence of a solid particulate material having an average particle size of from 1 to 500 mm.Type: GrantFiled: October 1, 2015Date of Patent: May 28, 2019Assignee: Xeros LimitedInventors: Addis Duki Feyisa, John Edward Steele
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Publication number: 20180058186Abstract: A method in one embodiment includes obtaining produced water from at least one of drilling, completion, or hydrocarbon production. The method also includes separating the produced water into desalinated water and produced salt. Further, the method includes coating the produced salt with resin to provide coated produced salt.Type: ApplicationFiled: August 31, 2016Publication date: March 1, 2018Inventors: Mahendra L. Joshi, Ryan Antle, Catherine James, Edward Steele, Brian Rovelli
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Publication number: 20180016528Abstract: A method of removing at least a portion of an oxide layer from the surface of a metal substrate comprising exposing the metal substrate to a body of treatment liquor comprising a treatment formulation and a multiplicity of solid particles which comprise or consists of a multiplicity of polymeric particles and wherein said treatment formulation comprises one or more promoters selected from the group consisting of acids, bases and surfactants wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement.Type: ApplicationFiled: March 3, 2014Publication date: January 18, 2018Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Patent number: 9845516Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with an aqueous treatment formulation and a solid particulate material in a sealed apparatus, wherein the aqueous treatment formulation comprises at least one colorant. There is also disclosed an animal substrate obtained by the method and finished leather goods obtained by the method.Type: GrantFiled: April 11, 2014Date of Patent: December 19, 2017Assignee: Xeros LimitedInventor: John Edward Steele
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Publication number: 20160251602Abstract: A method of cleaning a metal substrate, the method comprising exposing the metal substrate to a body of cleaning liquor comprising a cleaning formulation and a multiplicity of solid particles wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement; wherein i) the cleaning formulation comprises at least one acid which has a pKa greater than about ?1.7; and/or ii) the cleaning formulation comprises at least one base which has a pKb greater than about ?1.7; and the length of the particles is from about 0.5 mm to about 6 mm.Type: ApplicationFiled: March 3, 2014Publication date: September 1, 2016Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Publication number: 20160251603Abstract: A method of removing at least a portion of an oxide layer from the surface of a metal substrate comprising exposing the metal substrate to a body of treatment liquor comprising a treatment formulation and a multiplicity of solid particles which comprise or consists of a multiplicity of polymeric particles and wherein said treatment formulation comprises one or more promoters selected from the group consisting of acids, bases and surfactants wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement.Type: ApplicationFiled: March 3, 2014Publication date: September 1, 2016Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Publication number: 20150152357Abstract: The invention provides a cleaning formulation comprising a multiplicity of solid cleaning particles, wherein the solid cleaning particles comprise polymeric particles and at least one cleaning agent, wherein the at least one cleaning agent is immobilised on the surface of the polymeric particles. Typically the at least one cleaning agent is immobilised on the surface of the polymeric particles by means of chemical bonds, typically ionic bonds, hydrogen bonds, covalent bonds, polar bonds, or bonds formed by virtue of unequal charge distributions between polymeric particles and immobilised materials. The invention also provides a method for the cleaning of a substrate, the method comprising the treatment of the substrate with a formulation according to the invention, and a method for the preparation of the cleaning formulation of the invention which comprises treating a multiplicity of polymeric particles with at least one cleaning agent.Type: ApplicationFiled: July 8, 2013Publication date: June 4, 2015Applicant: XEROS LIMITEDInventors: Elizabeth Jean Abercrombie, Ana America Tellechea Lopez, John Edward Steele, Stephen Derek Jenkins
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Publication number: 20130167882Abstract: The invention provides a method for the treatment of polymeric particles recovered after use in cleaning processes for soiled substrates, the method comprising treating the particles with a particle cleaning agent. Preferably, said agent comprises at least one surfactant. Preferably said agent comprises an aqueous medium. Typically, the polymeric particles comprise particles of nylon or polyester. The invention also provides a method for cleaning a soiled substrate, the method comprising the steps of: (a) treating polymeric particles with a particle cleaning agent; and (b) treating a moistened substrate with a formulation comprising a multiplicity of said treated polymeric particles. Most preferably, the substrate comprises a textile fibre or fabric.Type: ApplicationFiled: September 14, 2011Publication date: July 4, 2013Applicant: XEROS LIMITEDInventors: Stephen Martin Burkinshaw, Stephen Derek Jenkins, Frazer John Kennedy, John Edward Steele
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Patent number: 8356441Abstract: A pistol magazine loader device. The pistol magazine loader device includes a housing designed to receive a magazine. A control element, whose movement is directed by a handle device, coordinates the movement of a plunger designed to push a magazine follower or first cartridge resident at a top of the magazine down into the magazine and a cartridge pusher that pushes a second cartridge into the magazine.Type: GrantFiled: January 13, 2010Date of Patent: January 22, 2013Assignee: GemOptics LLCInventor: Edward Steele Meinel
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Publication number: 20100175294Abstract: A pistol magazine loader device. The pistol magazine loader device includes a housing designed to receive a magazine. A control element, whose movement is directed by a handle device, coordinates the movement of a plunger designed to push a magazine follower or first cartridge resident at a top of the magazine down into the magazine and a cartridge pusher that pushes a second cartridge into the magazine.Type: ApplicationFiled: January 13, 2010Publication date: July 15, 2010Inventor: Edward Steele Meinel
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Patent number: D630687Type: GrantFiled: January 21, 2009Date of Patent: January 11, 2011Inventor: Edward Steele Meinel