Patents by Inventor Edward Suarez-Moreira

Edward Suarez-Moreira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of synthesis of a salt of N-acetyl-L-cysteinylcobalamin
    Patent number: 7777046
    Abstract: The invention provides a method for preparing the sodium salt of the novel thiol derivative of vitamin B12, N-acetyl-L-cysteinylcobalamin (Na[NACCbl]). The method involves carrying out the reaction in aqueous solvent with a relatively small excess of ligand reactant, specifically from one to less than four molar equivalents. The cobalamin derivative formed is precipitated from the aqueous solvent, preferably by the addition of a precipitate inducing solvent. This provides a product in acceptable purity without the need for an additional chromatographic purification step.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: August 17, 2010
    Assignee: Kent State University
    Inventors: Nicola E Brasch, Edward Suarez-Moreira
  • Method of synthesis of the sodium salt of N-acetyl-L-cysteinylcobalamin
    Publication number: 20080234489
    Abstract: The invention provides a method for preparing the sodium salt of the novel thiol derivative of vitamin B12, N-acetyl-L-cysteinylcobalamin (Na[NACCbl]). The method involves carrying out the reaction in aqueous solvent with a relatively small excess of ligand reactant, specifically from one to less than four molar equivalents. The cobalamin derivative formed is precipitated from the aqueous solvent, preferably by the addition of a precipitate inducing solvent. This provides a product in acceptable purity without the need for an additional chromatographic purification step.
    Type: Application
    Filed: March 20, 2007
    Publication date: September 25, 2008
    Inventors: Nicola D. Brasch, Edward Suarez-Moreira