Abstract: CD37-specific bispecific antibody molecules binding to different epitopes of the human CD37 antigen which bispecific antibody molecules have enhanced Fc-Fc interactions upon binding to CD37 on the cell surface. The invention also relates to the monoclonal parental antibodies from which the first or the second binding region of the bispecific antibody molecules is obtained. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of cancer and other diseases using these compositions.

Abstract: Computerized systems and methods are provided for automatically generating an application overflow tool that is dynamically updated and arranged to provide improved access to popular or recently used applications. These systems and methods improve existing technologies by generating an overflow panel different from a task bar, such that the overflow panel provides access to most recently used applications that are not on the task bar. As such, ease of access to applications is improved to increase user efficiency. These systems also improve the way computers operate by leveraging existing GUI layouts to reduce computing resource consumption, such as memory, network latency, I/O, and the like, that would otherwise be required improve access to applications.

Abstract: Methods, systems, and apparatus for brain tractography by shading fiber bundles. In one aspect, a method includes forwarding patient brain data for presentation to a user; receiving, from the user, a selection of a brain parcel in response to presentation of the patient brain data; forwarding, for display to the user, tract health data comprising i) tract data for tracts connected to the brain parcel and ii) at least one metric for the tracts, the metric reflecting the health of the tracts; and taking an action in response to forwarding the tract health data.

Abstract: A speaker can have a main body with a generally spheroidal shape, which can be supported standing on its end. The speaker can include a subwoofer that faces forward. A plurality of mid-range drivers can be distributed around the sub-woofer, facing generally forward and radially outward. A plurality of tweeters can be distributed around the sub-woofer, facing generally forward and generally outward. The outer housing portion of the speaker can be covered with a fabric material. A user interface ring 162 can be touch sensitive to receive input, and can have a plurality of lights that can be illuminated separately to convey information to the user.

Abstract: CD37-specific bispecific antibody molecules binding to different epitopes of the human CD37 antigen which bispecific antibody molecules have enhanced Fc-Fc interactions upon binding to CD37 on the cell surface. The invention also relates to the monoclonal parental antibodies from which the first or the second binding region of the bispecific antibody molecules is obtained. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of cancer and other diseases using these compositions.

Abstract: Methods, systems and apparatus, including computer programs encoded on computer storage media for fleet management of unmanned aerial vehicles, including flight authorization. One of the methods includes maintaining one or more rules associated with authorizing UAVs to implement flight plans. A request to generate a flight plan associated with a job is received, the request including information indicating a flight pattern comprising, at least, one or more waypoints associated with geospatial references. The flight plan is generated based on the request, and an initial authorization check is determined based on the maintained rules and the generated flight plan. Upon a positive determination, access to the generated flight plan is provided by a ground control system, and the flight plan is implemented.

Abstract: Disclosed herein is a power generating apparatus for extracting energy from flowing water. The apparatus comprises a buoyancy vessel, and a turbine assembly coupled to the buoyancy vessel which comprises a turbine rotor mounted to a nacelle, and a support structure. The turbine assembly is pivotally moveable between a first position and a second position. When the power generating apparatus is floating on a body of water, in the first position the nacelle is fully submerged below the water surface; and in the second position at least a part of the nacelle projects above the water surface. Movement of the turbine assembly from the first position to the second position is buoyancy assisted, for example by providing the turbine assembly with positive buoyancy or selectively increasing its buoyancy.

Abstract: The invention provides novel antibacterial compounds of formulae IA, IB and IC as defined herein. Optionally, the antibacterial compounds can be bonded to a delivery agent that is capable of bonding to one or more structures on a bacterial cell membrane. The invention also provides the use of such compounds in treating or preventing bacterial infections, and processes for their synthesis.

Abstract: Computerized systems and methods are provided for automatically generating an application overflow tool that is dynamically updated and arranged to provide improved access to popular or recently used applications. These systems and methods improve existing technologies by generating an overflow panel different from a task bar, such that the overflow panel provides access to most recently used applications that are not on the task bar. As such, ease of access to applications is improved to increase user efficiency. These systems also improve the way computers operate by leveraging existing GUI layouts to reduce computing resource consumption, such as memory, network latency, I/O, and the like, that would otherwise be required improve access to applications.

Abstract: A composition (or an aggregate) comprising a h-BN/BNNT structure that comprises a boron nitride nanotube structure and at least a first hexagonal boron nitride structure. Also, a composition comprising at least a first epitaxial h-BN/BNNT structure and at least one metal adhered to the first epitaxial h-BN/BNNT structure. Also, a composition (or an aggregate) that comprises independent boron nitride nanotubes, in which a total mass percentage of independent hexagonal boron nitride and residual boron in the composition is not more than 35%. Also, a material comprising at least a first hexagonal boron nitride structure and at least a first boron nitride nanotube structure, wherein atoms in the first hexagonal boron nitride structure are epitaxially aligned with atoms in the first boron nitride nanotube structure that are closest to the first hexagonal boron nitride structure.

Abstract: An improvement for use with a door latch assembly for a roll-up door includes a shim dimensioned and shaped to be positioned over a latch cover of the latch door assembly and to be slidingly moved to a shim extended position wherein a shim tang extends beyond a latch slide tang of the latch assembly. The shim is configured so that, if the latch assembly is mounted to a rolling door and is locked into an unsecured position by a first lock, wherein the slide tang does not engage the door jamb, the shim can be moved to and locked in the shim extended position to secure the rolling door without removing the first lock.

Abstract: Systems, computer program products, and methods are described herein for securely managing device communication. The present invention may be configured to provide, to another system, staging information including a digital certificate, a PIN, and a protocol for storing on a device, receive from the device a request to connect to an internal network after user input of the PIN, receive a digital certificate from the device, establish a wireless connection between the device and the internal network, and cause the device to delete the PIN. In some embodiments, the system is configured to permit communication from the device to the other system for a predetermined time window. In some embodiments, the system receives updates from the other system, via an external network, and the system sends the updates to the device, via the internal network.

Abstract: Systems, computer program products, and methods are described herein for secure resource allocation communication with a network. The present invention may be configured to provide, to a device management system, a request for authentication and receive, from the device management system, a file including a link to a certificate system. The present invention may be further configured to provide, using the link, a certificate enrollment request to the certificate system and receive, from the certificate system, a signed certificate. The present invention may be further configured to establish, using the signed certificate, a wireless connection to a network. In some embodiments, the present invention may include a scanner device for processing instruments associated with resource allocations and a network device communicatively connected to the scanner device for enabling the scanner device to communicate wirelessly with the network.

Abstract: A seller provides customers with the ability to order items using shipping benefits associated with a separate fulfillment entity, such as an online store, by providing inventory to a designated fulfilment location. When a customer accesses the webpage, identifiers for the customer device and item are used to determine an estimated delivery time the separate fulfillment entity may provide, which may be presented in a widget or other type of element within the webpage. In response to input to the element, the customer may be presented with a prompt for authentication data, and after a successful authentication, the estimated delivery time may be updated based on a location of the authenticated customer. In response to input confirming the transaction, an order for the item is generated by the separate fulfillment entity and the customer may continue navigating the seller website.

Abstract: The invention provides a combination of an antibacterial agent and a delivery agent, in which the delivery agent is bonded, or capable of binding, to the antibacterial agent, and in which the delivery agent is capable of binding to one or more structures on a bacterial cell membrane. The invention further provides the use of such combinations in treating or preventing bacterial infections.

Abstract: The invention provides a combination of an antibacterial agent (in particular vancomycin or moenomycin) and a delivery agent, in which the delivery agent is bonded, or capable of binding, to the antibacterial agent, and in which the delivery agent is capable of binding to one or more structures on a bacterial cell membrane. The invention further provides the use of such combinations in treating or preventing bacterial infections.

Abstract: An exercise bike operable while remaining stationary on a support surface. The exercise bike includes a bicycle frame with a pedal assembly coupled to a clutch mechanism that is movable between an unlocked state in which the pedal assembly drives a wheel in a first rotational direction and rotates relative to the wheel in a second rotational direction, and a locked state in which the pedal assembly is rotationally fixed to the wheel to drive the wheel in the first rotational direction and the second rotational direction, and a handlebar assembly. The handlebar assembly is coupled to the bicycle frame and includes a handlebar and a locking mechanism. The locking mechanism is moveable between an unlocked position in which the handlebar is allowed to rotate about an axis, and a locked position in which the handlebar is restricted from rotating about the axis. A control module may move the locking mechanism and the clutch mechanism between their respective locked and unlocked states.

Abstract: Disclosed herein are automated trading engine embodiments that operate on market data and re-engineer trading logic to operate on computational resources that are capable of providing highly parallelized processing operations to improve tick to trade latency. As an example, logic resources for the automated trading engine can implement aggressing strategies to place aggressing orders on markets when defined conditions are met. Further still, the aggressing strategies can be driven by low latency derivative pricing.

Abstract: Computerized systems and methods are provided for automatically generating an application overflow tool that is dynamically updated and arranged to provide improved access to popular or recently used applications. These systems and methods improve existing technologies by generating an overflow panel different from a task bar, such that the overflow panel provides access to most recently used applications that are not on the task bar. As such, ease of access to applications is improved to increase user efficiency. These systems also improve the way computers operate by leveraging existing GUI layouts to reduce computing resource consumption, such as memory, network latency, I/O, and the like, that would otherwise be required improve access to applications.

Abstract: Disclosed herein are automated trading engine embodiments that operate on market data and re-engineer trading logic to operate on computational resources that are capable of providing highly parallelized and pipelined processing operations to improve tick to trade latency. As an example, logic resources for the automated trading engine can implement canceling strategies to cancel quotes and/or orders on markets when defined conditions are met. For example, if new trades indicate that existing quotes and/or orders are no longer advantageous, the logic resources can act quickly to cancel those quotes and/or orders.