Patents by Inventor Edward Thomas Kisak

Edward Thomas Kisak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOPICAL FORMULATION
    Publication number: 20200383910
    Abstract: Provided herein are topical formulations. The topical formulation may comprise: (i) pregabalin, (ii) water, (iii) DMSO, (iv) a keto acid, and (v) and/or a fatty alcohol. The topical formulation may also comprise (i) pregabalin, (ii) DMSO, (iii) a keto acid and (iv) a fatty acid ester. It has been discovered that the combinations of DMSO with a keto acid such as levulinic acid and/or and a fatty acid ester such as lauryl lactate, or combinations of DMSO with a keto acid such as levulinic acid and/or with a fatty alcohol such as oleyl alcohol are excellent penetration enhancers and, as such, can be incorporated in a skin-applied formulation to facilitate administration of pregabalin.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 10, 2020
    Inventors: Edward Thomas Kisak, John Michael Newsam, Servet Buyuktimkin, Nadir Buyuktimkin
  • Topical formulation
    Patent number: 10716754
    Abstract: Provided herein are topical formulations. The topical formulation may comprise: (i) pregabalin, (ii) water, (iii) DMSO, (iv) a keto acid, and (v) and/or a fatty alcohol. The topical formulation may also comprise (i) pregabalin, (ii) DMSO, (iii) a keto acid and (iv) a fatty acid ester. It has been discovered that the combinations of DMSO with a keto acid such as levulinic acid and/or and a fatty acid ester such as lauryl lactate, or combinations of DMSO with a keto acid such as levulinic acid and/or with a fatty alcohol such as oleyl alcohol are excellent penetration enhancers and, as such, can be incorporated in a skin-applied formulation to facilitate administration of pregabalin.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: July 21, 2020
    Assignee: Tioga Research, Inc.
    Inventors: Edward Thomas Kisak, John Michael Newsam, Servet Buyuktimkin, Nadir Buyuktimkin
  • COMPOSITIONS FOR DRUG DELIVERY
    Publication number: 20190008969
    Abstract: The present disclosure relates generally to compositions and formulations of active agents for improved delivery of the active agents, methods of making such compositions or formulations, and methods of use thereof. Also described herein are compositions comprising isopropyl palmitate and formulations thereof for drug delivery of an active agent.
    Type: Application
    Filed: July 6, 2017
    Publication date: January 10, 2019
    Inventors: Edward Thomas Kisak, John Michael Newsam, Avadhesh Kushwaha
  • TOPICAL FORMULATION
    Publication number: 20170290769
    Abstract: Provided herein are topical formulations. The topical formulation may comprise: (i) pregabalin, (ii) water, (iii) DMSO, (iv) a keto acid, and (v) and/or a fatty alcohol. The topical formulation may also comprise (i) pregabalin, (ii) DMSO, (iii) a keto acid and (iv) a fatty acid ester. It has been discovered that the combinations of DMSO with a keto acid such as levulinic acid and/or and a fatty acid ester such as lauryl lactate, or combinations of DMSO with a keto acid such as levulinic acid and/or with a fatty alcohol such as oleyl alcohol are excellent penetration enhancers and, as such, can be incorporated in a skin-applied formulation to facilitate administration of pregabalin.
    Type: Application
    Filed: March 27, 2017
    Publication date: October 12, 2017
    Inventors: Edward Thomas Kisak, John Michael Newsam, Servet Buyuktimkin, Nadir Buyuktimkin