Patents by Inventor Edward W. Badger

Edward W. Badger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor
    Patent number: 4772607
    Abstract: The present invention is various novel diallyl analogs of xanthine. Additionally, the invention is pharmaceutical compositions having as the active compound diallyl analogs of xanthines and methods of use therefor. Processes of preparation of diallyl analogs of xanthine are also the invention. The use of the analogs relates particularly to a desirable affinity at adenosine receptors, particularly the A.sub.1 receptor. The analogs are adenosine receptor antagonists. The analogs, thus, for example provide activity for use as a CNS stimultant cognition activator, antifibrillatory agent, and bronchodilator.
    Type: Grant
    Filed: July 14, 1986
    Date of Patent: September 20, 1988
    Assignee: Warner-Lambert Company
    Inventors: Edward W. Badger, Harriet W. Hamilton
  • 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
    Patent number: 4732898
    Abstract: The present invention are 2-(2-aryl-2-oxo-alkylidene) analogs of 1,2,3,4-tetrahydropyridine-3,5-pyridinecarboxylic acids and particularly esters thereof having valuable calcium antagonist and positive inotropic activity useful in the treatment of cardiovascular disorders, pharmaceutical compositions and methods of use therefor.
    Type: Grant
    Filed: March 3, 1987
    Date of Patent: March 22, 1988
    Assignee: Warner-Lambert Company
    Inventors: Edward W. Badger, Michael D. Taylor
  • 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
    Patent number: 4678796
    Abstract: Novel 2-(2-alkoxy-2-oxoethylidene)-1,2,3,4-tetrahydro-6-methyl-4-[2-(substituted )phenyl]-3,5-pyridinedicarboxylic acid dialkyl ester derivatives having novel inotropic and hypotensive activity, processes for their manufacture, pharmaceutical compositions, and methods for using said compounds and compositions are described.
    Type: Grant
    Filed: September 3, 1986
    Date of Patent: July 7, 1987
    Assignee: Warner-Lambert Company
    Inventors: Michael D. Taylor, Edward W. Badger
  • Substituted 8-phenylxanthines
    Patent number: 4452788
    Abstract: Substituted 8-phenylxanthines and their use as bronchodilators is described. Methods for their preparation and use as well as pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 21, 1982
    Date of Patent: June 5, 1984
    Assignee: Warner-Lambert Company
    Inventors: James A. Bristol, Edward W. Badger