Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.

Abstract: Various embodiments of a low-height heat pump cabinet are disclosed. An example heat pump system includes a low-height cabinet configured to be mounted to a ceiling. The low-height cabinet includes a frame and a plurality of panels that define a compressor compartment, a blower compartment, and a plenum compartment. The frame includes one or more dividers that separate the blower compartment, the plenum compartment, and the compressor compartment from each other. The example heat pump system also includes a compressor installed horizontally in the compressor compartment, a heat exchanger installed vertically in the compressor compartment, a blower assembly installed in the blower compartment, and an air coil installed in the blower compartment.

Abstract: A network of collection and distribution machines may collect, charge and/or distribute portable electrical energy storage devices (e.g., batteries, supercapacitors or ultracapacitors). Electric vehicles available for sharing, renting or otherwise available for temporary use may be located at such collection and distribution machines or other designated areas. Users may request temporary use of such electric vehicles via a user interface of the collection and distribution machine, the user's mobile device or that of the electric vehicle itself. During temporary use, the user may exchange depleted portable electrical energy storage devices of the vehicle being used for charged portable electrical energy storage devices at the collection and distribution machines and may be offered the opportunity to terminate the temporary use session or continue the temporary use session in conjunction with the portable electrical energy storage device exchange.

Abstract: The present disclosure relates to apparatus and methods for locking and/or unlocking a vehicle based on a location of a mobile device associated with the vehicle. In one embodiment a processor in a vehicle analyzes a position of a mobile device relative to the vehicle and allows the vehicle to be unlocked when the mobile device is determined to be approaching the vehicle.

Abstract: A network of collection and distribution machines may collect, charge and/or distribute portable electrical energy storage devices (e.g., batteries, supercapacitors or ultracapacitors). Electric vehicles available for sharing, renting or otherwise available for temporary use may be located at such collection and distribution machines or other designated areas. Users may request temporary use of such electric vehicles via a user interface of the collection and distribution machine, the user's mobile device or that of the electric vehicle itself. During temporary use, the user may exchange depleted portable electrical energy storage devices of the vehicle being used for charged portable electrical energy storage devices at the collection and distribution machines and may be offered the opportunity to terminate the temporary use session or continue the temporary use session in conjunction with the portable electrical energy storage device exchange.

Abstract: An exemplary lock cylinder includes a shell, a plug positioned in the shell, and a locking assembly. The locking assembly is configured to prevent rotation of the plug when no key is inserted, and to permit rotation of the plug upon insertion of any of a plurality of keys having different bitting profiles. The locking assembly may further be configured to prevent key extraction when the plug is in a rotated position.

Abstract: The present disclosure relates to apparatus and methods for locking and/or unlocking a vehicle based on a location of a mobile device associated with the vehicle. In one embodiment a processor in a vehicle analyzes a position of a mobile device relative to the vehicle and allows the vehicle to be unlocked when the mobile device is determined to be approaching the vehicle.

Abstract: An exemplary lock cylinder includes a shell, a plug positioned in the shell, and a locking assembly. The locking assembly is configured to prevent rotation of the plug when no key is inserted, and to permit rotation of the plug upon insertion of any of a plurality of keys having different bitting profiles. The locking assembly may further be configured to prevent key extraction when the plug is in a rotated position.

Abstract: A door lock chassis has a gauge insert that defines different dimensions corresponding to different door thicknesses. The gauge insert is positionable in the lock chassis in different orientations corresponding to the different dimensions used to align the lock chassis for different door thicknesses. Additionally, a door lock may include an anti-rotation assembly for preventing rotation of the lock chassis. The anti-rotation assembly may include a retention member that is secured to an inside hub of a lock chassis. As an anti-rotation member is displaced in a first axial direction along the inside hub to a mount position, the anti-rotational member may deflect resilient members of the retention member. With the anti-rotation member at the mounted position, the anti-rotation member may be in a frictional engagement with the previously deflected resilient members so that anti-rotation member is retained at the mount position.

Abstract: In an exemplary embodiment, a plug assembly includes a plug body, a sidebar, a cover plate, and a plurality of rack pins positioned in the plug assembly. A first portion of the sidebar is positioned in the plug and a second portion protrudes beyond the outer surface of the plug body. The rack pins are configured to selectably resist and permit radially inward motion of the sidebar. The cover plate is operable to selectably retain the rack pins within the plug body.

Abstract: A retention mechanism for retaining a lock cylinder in a lock housing. The retention mechanism includes a control lug, a control pin, and a finger pin. A portion of the control lug is configured to be positioned in a retention recess of the lock housing when the control lug is in an engagement position to prevent the removal of the lock cylinder from the lock housing. With the control lug in the engaged position, at least a portion of the control pin may be biased into a chamber of the control lug to retain the control lug at the engaged position. When the control lug is to be displaced from the engaged position, the finger pin may be lifted to an activation position, such as by a sidebit of a key, wherein the finger pin may removably displace the control pin from at least a portion of the chamber.

Abstract: A network of collection and distribution machines may collect, charge and/or distribute portable electrical energy storage devices (e.g., batteries, supercapacitors or ultracapacitors). Electric vehicles available for sharing, renting or otherwise available for temporary use may be located at such collection and distribution machines or other designated areas. Users may request temporary use of such electric vehicles via a user interface of the collection and distribution machine, the user's mobile device or that of the electric vehicle itself. During temporary use, the user may exchange depleted portable electrical energy storage devices of the vehicle being used for charged portable electrical energy storage devices at the collection and distribution machines and may be offered the opportunity to terminate the temporary use session or continue the temporary use session in conjunction with the portable electrical energy storage device exchange.

Abstract: A network of collection and distribution machines may collect, charge and/or distribute portable electrical energy storage devices (e.g., batteries, supercapacitors or ultracapacitors). Electric vehicles available for sharing, renting or otherwise available for temporary use may be located at such collection and distribution machines or other designated areas. Users may request temporary use of such electric vehicles via a user interface of the collection and distribution machine, the user's mobile device or that of the electric vehicle itself. During temporary use, the user may exchange depleted portable electrical energy storage devices of the vehicle being used for charged portable electrical energy storage devices at the collection and distribution machines and may be offered the opportunity to terminate the temporary use session or continue the temporary use session in conjunction with the portable electrical energy storage device exchange.

Abstract: A progressive key notching system that includes a plurality of key notches positioned along at least one surface, such as, for example, a top surface, of a key blade. Each of the plurality of key notches includes a central axis. The central axes of at least one pair of adjacent key notches are separated by a distance that is different than a distance separating another, adjacent pair of key notches. Further, when the key blade is operably positioned within a key slot, at least one of the central axes may be offset from a chamber central axis of an adjacent retention pin chamber. Moreover, one or more of the chamber central axes may be aligned with a portion of a trailing surface and/or leading surface of an adjacent key notch.

Abstract: A plug assembly for a lock includes a generally cylindrical plug body that defines a keyway and a generally cylindrical plug housing that rotatably receives the plug body. A plurality of blocking members are housed in the plug body and are movable into the keyway upon rotation of the plug body relative to the plug housing to obstruct the keyway. A key can be provided that is positionable into the keyway, and the blade of the key defines receptacles for receiving the blocking members when the plug body is rotated so that the lock can be unlocked. However, the blocking members prevent rotation of the plug body when a picking tool or unauthorized key is inserted in the keyway since either the blocking members cannot move into the keyway and remain engaged to the plug housing due to the object in the keyway, or obstruct the keyway and prevent insertion of the picking tool.

Abstract: A plug assembly for a lock includes a generally cylindrical plug body that defines a keyway and a generally cylindrical plug housing that rotatably receives the plug body, A plurality of blocking members are housed in the plug body and are movable into the keyway upon rotation of the plug body relative to the plug housing to obstruct the keyway. A key can be provided that is positionable into the keyway, and the blade of the key defines receptacles for receiving the blocking members when the plug body is rotated so that the lock can be unlocked. However, the blocking members prevent rotation of the plug body when a picking tool or unauthorized key is inserted in the keyway since either the blocking members cannot move into the keyway and remain engaged to the plug housing due to the object in the keyway, or obstruct the keyway and prevent insertion of the picking tool.

Abstract: A plug assembly including, a plug, a sidebar movably mounted on the plug, and a plurality of rack pins seated in the plug. The sidebar is biased to an outer position in which the sidebar extends beyond an outer surface of the plug. Each rack pin is a single-piece unitary structure including a key-following leg, and a sidebar-engaging leg. The sidebar-engaging leg includes at least one true gate and a plurality of false gates. When a true gate of each rack pin is aligned with the sidebar, the sidebar is free to move radially inward to an inner position.

Abstract: A plug assembly including, a plug, a sidebar movably mounted on the plug, and a plurality of rack pins seated in the plug. The sidebar is biased to an outer position in which the sidebar extends beyond an outer surface of the plug. Each rack pin is a single-piece unitary structure including a key-following leg, and a sidebar-engaging leg. The sidebar-engaging leg includes at least one true gate and a plurality of false gates. When a true gate of each rack pin is aligned with the sidebar, the sidebar is free to move radially inward to an inner position.

Abstract: In an exemplary embodiment, a plug assembly includes a plug body, a sidebar, a cover plate, and a plurality of rack pins positioned in the plug assembly. A first portion of the sidebar is positioned in the plug and a second portion protrudes beyond the outer surface of the plug body. The rack pins are configured to selectably resist and permit radially inward motion of the sidebar. The cover plate is operable to selectably retain the rack pins within the plug body.

Abstract: A retention mechanism for retaining a lock cylinder in a lock housing. The retention mechanism includes a control lug, a control pin, and a finger pin. A portion of the control lug is configured to be positioned in a retention recess of the lock housing when the control lug is in an engagement position to prevent the removal of the lock cylinder from the lock housing. With the control lug in the engaged position, at least a portion of the control pin may be biased into a chamber of the control lug to retain the control lug at the engaged position. When the control lug is to be displaced from the engaged position, the finger pin may be lifted to an activation position, such as by a sidebit of a key, wherein the finger pin may removably displace the control pin from at least a portion of the chamber.