Patents by Inventor Edward Yat Wah Tom

Edward Yat Wah Tom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of diagnosis of Hepatitis C infection, compositions and methods of screening for modulators of Hepatitis C infection
    Publication number: 20030228570
    Abstract: Described herein are genes whose expression are up-regulated or down-regulated during the course of Hepatitis C infection, or distinction between treatment response. Related methods and compositions that can be used for diagnosis and treatment of Hepatitis C infection and/or its secondary consequences are disclosed. Also described herein are methods that can be used to identify modulators of Hepatitis C infection and/or its secondary consequences.
    Type: Application
    Filed: February 12, 2003
    Publication date: December 11, 2003
    Applicant: Eos Biotechnology, Inc.
    Inventors: Edward Yat Wah Tom, Albert Zlotnik
  • P53-regulated genes
    Publication number: 20010039013
    Abstract: Many genes are identified as being p53-regulated which were not heretofore known to be p53-regulated. This includes both genes whose expression is induced and genes whose expression is repressed by the expression of wild-type p53. Monitoring expression of these genes is used to provide indications of p53 status in a cell. Such monitoring can also be used to screen for useful anti cancer therapeutics, as well as for substances which are carcinogenic. Defects in p53 can be bypassed by supplying p53 induced genes to cells. Defects in p53 can also be bypassed by supplying antisense constructs to p53-repressed genes.
    Type: Application
    Filed: January 8, 2001
    Publication date: November 8, 2001
    Inventors: Arnold L. Levine, Maureen Elizabeth Murphy, David H. Mack, Kurt Carlyle Gish, Edward Yat Wah Tom
  • P53-regulated genes
    Patent number: 6171798
    Abstract: Many genes are identified as being p53-regulated which were not heretofore known to be p53-regulated. This includes both genes whose expression is induced and genes whose expression is repressed by the expression of wild-type p53. Monitoring expression of these genes is used to provide indications of p53 status in a cell. Such monitoring can also be used to screen for useful anti-cancer therapeutics, as well as for substances which are carcinogenic. Defects in p53 can be bypassed by supplying p53 induced genes to cells. Defects in p53 can also be bypassed by supplying antisense constructs to p53-repressed genes.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: January 9, 2001
    Assignees: Affymetrix, Inc., Princeton University
    Inventors: Arnold L. Levine, Maureen Elizabeth Murphy, David H. Mack, Kurt Carlyle Gish, Edward Yat Wah Tom
  • P53-regulated genes
    Patent number: 6020135
    Abstract: Many genes are identified as being p53-regulated which were not heretofore known to be p53-regulated. This includes both genes whose expression is induced and genes whose expression is repressed by the expression of wild-type p53. Monitoring expression of these genes is used to provide indications of p53 status in a cell. Such monitoring can also be used to screen for useful anti-cancer therapeutics, as well as for substances which are carcinogenic. Defects in p53 can be bypassed by supplying p53 induced genes to cells. Defects in p53 can also be bypassed by supplying antisense constructs to p53-repressed genes.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: February 1, 2000
    Assignees: Affymetrix, Inc., Princeton University
    Inventors: Arnold J. Levine, Maureen Elizabeth Murphy, David H. Mack, Kurt Carlyle Gish, Edward Yat Wah Tom