Patents by Inventor Edwards Allen

Edwards Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR SHORT STATURE PLANTS THROUGH MANIPULATION OF GIBBERELLIN METABOLISM
    Publication number: 20250277194
    Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn plants. Methods and compositions are provided for ectopically or transgenically expressing a GA2 oxidase in corn plants. Modified plants, plant parts and plant cells having a recombinant DNA construct for expression of a GA2 oxidase transgene are further provided that may comprise reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
    Type: Application
    Filed: December 15, 2021
    Publication date: September 4, 2025
    Applicant: Monsanto Technology LLC
    Inventors: Edwards ALLEN, Jayanand BODDU, Alexander GOLDSHMIDT, Anil NEELAM, Tomasz PACIOREK, Thomas SLEWINSKI, Huai WANG
  • METHODS AND COMPOSITIONS FOR SHORT STATURE PLANTS THROUGH MANIPULATION OF GIBBERELLIN METABOLISM TO INCREASE HARVESTABLE YIELD
    Publication number: 20230110884
    Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
    Type: Application
    Filed: June 22, 2022
    Publication date: April 13, 2023
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards Allen, Jayanand BODDU, Charles R. DIETRICH, Alexander GOLDSHMIDT, Miya HOWELL, Kevin R. KOSOLA, Silvalinganna MANJUNATH, Anil NEELAM, Linda RYMARQUIS, Thomas L. SLEWINSKI, Tyamagondlu V. VENKATESH, Huai WANG
  • Methods and DNA Constructs for Autoregulating Transgene Silencing
    Publication number: 20210207155
    Abstract: This invention provides a method to autoregulate expression of a transgene susceptible to sRNA silencing by concomitantly transcribing RNA from DNA of a transgene and RNA from DNA from at least one sRNA silencing pathway gene. An aspect of the invention provides use of a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator. Also disclosed are transgenic cells and organisms having in their genome a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator.
    Type: Application
    Filed: March 18, 2021
    Publication date: July 8, 2021
    Applicant: Monsanto Technology LLC
    Inventors: Edwards Allen, Larry A. Gilbertson, Sergey I. Ivashuta, James K. Roberts
  • Methods for producing hybrid seed
    Patent number: 10876126
    Abstract: This invention provides methods for producing a non-natural hybrid seed. Also disclosed are specific miRNAs and miRNA recognition sites useful for conferring inducible sterility on a crop plant, and recombinant DNA construct including such exogenous miRNA recognition sites.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: December 29, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Larry A. Gilbertson, James K. Roberts, Nancy M. Houmard, Shihshieh Huang, Sergey Ivashuta
  • Invertebrate microRNAs
    Patent number: 10570414
    Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: February 25, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
  • Phased small RNAs
    Patent number: 10301623
    Abstract: This invention discloses recombinant DNA constructs encoding phased small RNAs useful in regulating expression of one or more genes of interest. Also disclosed by this invention are transgenic plant cells, plants, and seeds containing a recombinant DNA construct of this invention.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: May 28, 2019
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Liang Guo, Sara E. Heisel, Sergey I. Ivashuta, Yuanji Zhang
  • Method to trigger RNA interference
    Patent number: 10174338
    Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: January 8, 2019
    Assignee: Oregon State University
    Inventors: James C. Carrington, Edwards Allen
  • TRANSGENIC PLANTS WITH ENHANCED AGRONOMIC TRAITS
    Publication number: 20180237793
    Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced trait.
    Type: Application
    Filed: November 30, 2017
    Publication date: August 23, 2018
    Applicant: Monsanto Technology LLC
    Inventors: Eric D. Aasen, Mark Scott Abad, Edwards Allen, Thandoni Rao Ambika, Veena S. Anil, Alice Clara Augustine, Stephanie L. Back, Pranesh Badami, Amarjit Basra, Kraig L. Brustad, Molian Deng, Todd Dezwaan, Charles Dietrich, Stephen M. Duff, Karen K. Gabbert, Steve He, Bill L. Hendrix, Hongwu Jia, Vidya Kammaradi Ramanath Bhat, Balasulojini Karunanandaa, Kevin R. Kosola, Kempagangaiah Krishnamurthy, Ganesh Kumar, Saritha V. Kuriakose, Shantala Lakkanna, Mark E. Leibman, Linda Lutfiyya, Savitha Madappa, Sivalinganna Manjunath, Robert J. Meister, Bellur Narasimha Prasad, Sasha Preuss, Qungang Qi, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, S. Sangeetha, Scott Saracco, Chitresh Sharma, Vijay K. Sharma, Monnanda S. Rajani, Padmini Sudarshana, Rebecca L. Thompson-Mize, Srikanth Venkatachalayya, Tyamagondlu V. Venkatesh, Huai Wang, Jingrui Wu, Xiaoyun Wu, Xiaofeng Sean Yang, Qin Zeng, Jianmin Zhao
  • INVERTEBRATE MICRORNAS
    Publication number: 20170067076
    Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.
    Type: Application
    Filed: November 10, 2016
    Publication date: March 9, 2017
    Applicant: Monsanto Technology LLC
    Inventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
  • Invertebrate microRNAs
    Patent number: 9528121
    Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: December 27, 2016
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, William P. Donovan, Gregory R. Heck, James K. Roberts, Virginia Ursin, Yuanji Zhang
  • Method to trigger RNA interference
    Patent number: 9447429
    Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: September 20, 2016
    Assignee: Oregon State University
    Inventors: James C. Carrington, Edwards Allen
  • METHOD TO TRIGGER RNA INTERFERENCE
    Publication number: 20160257969
    Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 8, 2016
    Applicant: Oregon State University
    Inventors: James C. Carrington, Edwards Allen
  • Phased Small RNAs
    Publication number: 20160168569
    Abstract: This invention discloses recombinant DNA constructs encoding phased small RNAs useful in regulating expression of one or more genes of interest. Also disclosed by this invention are transgenic plant cells, plants, and seeds containing a recombinant DNA construct of this invention.
    Type: Application
    Filed: February 24, 2016
    Publication date: June 16, 2016
    Applicant: Monsanto Technology LLC
    Inventors: Edwards Allen, Liang Guo, Sara E. Heisel, Sergey I. Ivashuta, Yuanji Zhang
  • Method to trigger RNA interference
    Patent number: 9334506
    Abstract: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: May 10, 2016
    Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University
    Inventors: James C. Carrington, Edwards Allen
  • Phased small RNAs
    Patent number: 9309512
    Abstract: This invention discloses recombinant DNA constructs encoding phased small RNAs useful in regulating expression of one or more genes of interest. Also disclosed by this invention are transgenic plant cells, plants, and seeds containing a recombinant DNA construct of this invention.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: April 12, 2016
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Liang Guo, Sara E. Heisel, Sergey I. Ivashuta, Yuanji Zhang
  • Methods and DNA Constructs for Autoregulating Transgene Silencing
    Publication number: 20160068852
    Abstract: This invention provides a method to autoregulate expression of a transgene susceptible to sRNA silencing by concomitantly transcribing RNA from DNA of a transgene and RNA from DNA from at least one sRNA silencing pathway gene. An aspect of the invention provides use of a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator. Also disclosed are transgenic cells and organisms having in their genome a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 10, 2016
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards Allen, Larry A. Gilbertson, Sergey I. Ivashuta, James K. Roberts
  • Transgenic Plants with Enhanced Agronomic Traits
    Publication number: 20160060648
    Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of Arabidopsis thaliana heat stress transcription factor A-2, which is useful for imparting enhanced agronomic traits) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced trait.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards Allen, Veena S. Anil, Amarjit Basra, Christopher T. Bauer, Prasanna R. Bhat, Raghunatha P. Chari, Jaishree Chittoor, Paul Chomet, Karen K. Gabbert, Cara Griffith, Bill Hendrix, Alberto Iandolino, Hongwu Jia, Kevin R. Kosola, Saritha V. Kuriakose, Paul J. Loida, Linda L. Lutfiyya, Mingsheng Peng, Ying Peng, Bellur Narasimha Prasad, Monnanda S. Rajani, Monica P. Ravanello, Donald Todd, Srikanth Babu Venkatachalayya, Tyamagondlu V. Venkatesh, K. R. Vidya, Huai Wang
  • Methods for Producing Hybrid Seed
    Publication number: 20160032300
    Abstract: This invention provides methods for producing a non-natural hybrid seed. Also disclosed are specific miRNAs and miRNA recognition sites useful for conferring inducible sterility on a crop plant, and recombinant DNA construct including such exogenous miRNA recognition sites.
    Type: Application
    Filed: September 14, 2015
    Publication date: February 4, 2016
    Inventors: Edwards Allen, Larry A. Gilbertson, James K. Roberts, Nancy M. Houmard, Shihshieh Huang, Sergey Ivashuta
  • Methods and DNA constructs for autoregulating transgene silencing
    Patent number: 9222100
    Abstract: This invention provides a method to autoregulate expression of a transgene susceptible to sRNA silencing by concomitantly transcribing RNA from DNA of a transgene and RNA from DNA from at least one sRNA silencing pathway gene. An aspect of the invention provides use of a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator. Also disclosed are transgenic cells and organisms having in their genome a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: December 29, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Larry A. Gilbertson, Sergey I. Ivashuta, James K. Roberts
  • Methods for producing hybrid seed
    Patent number: 9192112
    Abstract: This invention provides methods for producing a non-natural hybrid seed. Also disclosed are specific miRNAs and miRNA recognition sites useful for conferring inducible sterility on a crop plant, and recombinant DNA construct including such exogenous miRNA recognition sites.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: November 24, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Larry A Gilbertson, James K Roberts, Nancy M Houmard, Shihshieh Huang, Sergey Ivashuta