Patents by Inventor Edwige Lorthiois

Edwige Lorthiois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3- or 4-monosubtituted phenol and thiophenol derivatives useful as H3 ligands
    Patent number: 7456164
    Abstract: The invention relates to 3- or 4-monosubstituted phenol and thiophenol derivatives of formula (I) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol and thiophenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: May 9, 2005
    Date of Patent: November 25, 2008
    Assignee: Pfizer, Inc
    Inventors: Patrick Bernardelli, Andrew Michael Cronin, Alexis Denis, Stephen Martin Denton, Henry Jacobelli, Mark Ian Kemp, Edwige Lorthiois, Fiona Rousseau, Delphine Serradeil-Civit, Fabrice Vergne
  • Spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
    Patent number: 7214676
    Abstract: The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III) in which X1, X2, X3, X4, X, Y, Z, A and Z1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: May 8, 2007
    Assignee: Warner-Lambert Company LLC
    Inventors: Patrick Bernardelli, Pierre Ducrot, Edwige Lorthiois, Febrice Vergne
  • New Spirotricyclic Derivatives and Their Use as Phosphodiesterase-7 Inhibitors
    Publication number: 20070049558
    Abstract: The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III) in which X1, X2, X3, X4, X, Y, Z, A and Z1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.
    Type: Application
    Filed: October 20, 2006
    Publication date: March 1, 2007
    Inventors: Patrick Bernardelli, Pierre Ducrot, Edwige Lorthiois, Fabrice Vergne
  • 3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands
    Publication number: 20050267095
    Abstract: The invention relates to 3- or 4-monosubstituted phenol and thiophenol derivatives of formula (I) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol and thiophenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: May 9, 2005
    Publication date: December 1, 2005
    Inventors: Patrick Bernardelli, Andrew Cronin, Alexis Denis, Stephen Denton, Henry Jacobelli, Mark Kemp, Edwige Lorthiois, Fiona Rousseau, Delphine Serradeil-Civit, Fabrice Vergne
  • Thiazol-2-yl-imine compounds as PDE-7 inhibitors
    Patent number: 6852720
    Abstract: A compound selected from those of formula (I): wherein: R1, R2, R3 are as defined in the description, and optionally, its optical isomers, N-oxide, and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same are useful as inhibitors of phosphosdiesterase-7.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: February 8, 2005
    Assignee: Pfizer Inc.
    Inventors: Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Pierre Ducrot
  • Spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
    Publication number: 20040214843
    Abstract: The invention provides compounds which are PDE7inhibitors, having the following formula (I), (II) and (III) 1
    Type: Application
    Filed: May 24, 2004
    Publication date: October 28, 2004
    Applicant: Pfizer Inc
    Inventors: Patrick Bernardelli, Pierre Ducrot, Edwige Lorthiois, Febrice Vergne
  • (4,2-disubstituted-thiazol-5-yl)amine compounds as PDE7 inhibitors
    Patent number: 6753340
    Abstract: A compound selected from those of formula (I): wherein R1a, R1b, R2, R3, are as defined in the description, and optionally, its optical isomers, N-oxide, and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same are useful as specific inhibitors of phosphosdiesterase-7 (PDE-7).
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: June 22, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Pierre Ducrot
  • (4,2-Disubstituted-thiazol-5-yl)amine compounds as PDE7 inhibitors
    Publication number: 20030191167
    Abstract: A compound selected from those of formula (I): 1
    Type: Application
    Filed: March 27, 2003
    Publication date: October 9, 2003
    Inventors: Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Pierre Ducrot
  • Thiazol-2-yl-imine compounds as PDE-7 inhibitors
    Publication number: 20030186988
    Abstract: A compound selected from those of formula (I): 1
    Type: Application
    Filed: March 27, 2003
    Publication date: October 2, 2003
    Inventors: Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Pierre Ducrot
  • Spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
    Publication number: 20020198198
    Abstract: The invention provides compounds which are PDE7inhibitors, having the following formula (I), (II) and (III) 1
    Type: Application
    Filed: March 19, 2002
    Publication date: December 26, 2002
    Inventors: Patrick Bernardelli, Pierre Ducrot, Edwige Lorthiois, Fabrice Vergne