Patents by Inventor Edwin Cuppen

Edwin Cuppen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically Modified Rat Models for Obesity and Diabetes
    Publication number: 20140041063
    Abstract: This invention relates to a genetically modified or chimeric rat cell whose genome comprises chromosomal alleles of an obesity-diabetes gene (especially, the Mc4r gene or Lep gene), wherein at least one of the two alleles contains a mutation, or the progeny of this cell. The obesity or diabetes gene may affect any of the pathways of obesity and diabetes. The obesity or diabetes gene may predispose the rat to a phenotype of obese and diabetic, lean and diabetic, obese and non-diabetic, non-obese and diabetic or any of the combinations thereof. In another aspect, the invention relates to a desired rat or a rat cell which contains a predefined, specific and desired alteration rendering the rat or rat cell predisposed to obesity or diabetes.
    Type: Application
    Filed: September 4, 2013
    Publication date: February 6, 2014
    Applicant: Transposagen Biopharmaceuticals, Inc.
    Inventors: Eric M. Ostertag, John Stuart Crawford, Edwin Cuppen