Patents by Inventor Edwin H. Beachey

Edwin H. Beachey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
    Patent number: 5162226
    Abstract: Non-virulent aro-Salmonella typhimurium bacterium is disclosed into which has been cloned a heterologous nucleotide sequence encoding for the expression of Streptococcal M protein antigen from S. pyogenes seratype 5, which is effective to elicit opsonic antibodies against Streptococcal infections. The bacterium is useful for vaccination against Streptococcus pyogenes bacteria.
    Type: Grant
    Filed: August 24, 1987
    Date of Patent: November 10, 1992
    Assignee: University of Tennessee Research Corp. (U.T.R.C.)
    Inventors: Edwin H. Beachey, Thomas P. Poirier, Michael A. Kehoe
  • Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
    Patent number: 5124153
    Abstract: Non-virulent bacteria are disclosed into which have been cloned heterologous nucleotide sequences encoded for the expression of Streptococcal M protein antigens, which are effective to elicit opsonic antibodies against Streptococcal infections. These bacteria are useful for vaccination against Streptococcus pyogenes bacteria.
    Type: Grant
    Filed: August 9, 1989
    Date of Patent: June 23, 1992
    Assignee: University of Tennessee Research Corp.
    Inventors: Edwin H. Beachey, Thomas P. Poirier, Michael A. Kehoe
  • Synthetic M proteins-streptococci type 5
    Patent number: 4919930
    Abstract: Synthetic peptide segments of protein Pep M5 containing epitopes capable of evoking type specific opsonic antibodies against streptococci when covalently linked to a protein carrier.
    Type: Grant
    Filed: May 1, 1986
    Date of Patent: April 24, 1990
    Assignee: University of Tennessee Research Corporation
    Inventors: Edwin H. Beachey, James B. Dale
  • Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant
    Patent number: 4728639
    Abstract: A polypeptide having the formula Asn-Phe-Ser-Thr-Ala-Asp-Ser-Ala-Lys-Ile-Lys-Thr-Leu-Glu-Ala-Glu-Lys-Ala-Al a-Leu-Ala-Ala-Arg-Lys-Ala-Asp-Leu-Glu-Lys-Ala-Leu-Glu-Gly-Ala-Met is conjugated to polylysine.
    Type: Grant
    Filed: January 2, 1986
    Date of Patent: March 1, 1988
    Assignee: University of Tennessee Research Corporation
    Inventor: Edwin H. Beachey
  • Synthetic M proteins - streptococci type 6
    Patent number: 4705684
    Abstract: Synthetic immunogenic peptides when linked to a suitable carrier elicit opsonic antibodies which are type specific for type IV streptococci are disclosed.
    Type: Grant
    Filed: March 14, 1986
    Date of Patent: November 10, 1987
    Assignee: The University of Tennessee Research Corporation
    Inventor: Edwin H. Beachey
  • Synthetic peptide compounds
    Patent number: 4695562
    Abstract: Peptide fragment of M protein of S. pyrogenes elecit opsonic antibodies which are type-specific for type 24 streptococci.
    Type: Grant
    Filed: December 11, 1985
    Date of Patent: September 22, 1987
    Assignee: Univ. of Tennessee Research Corp.
    Inventors: Edwin H. Beachey, Andre Tartar, Helene Gras-Masse, Michel Jolivet, Francoise Audibert, Louis Chedid
  • Synthetic polypeptide fragments
    Patent number: 4597967
    Abstract: Peptide fragments of streptococcal M protein named CB3, CB4, and CB5 and related synthetic peptides have been identified. When linked to a protein carrier which is polylysine the conjugates of CB3, CB4, CB5, and S-CB3 are capable of evoking type specific opsonic antibodies against streptococci.
    Type: Grant
    Filed: February 12, 1985
    Date of Patent: July 1, 1986
    Assignee: The University of Tennessee Research Corp.
    Inventor: Edwin H. Beachey
  • Synthetic polypeptide fragments
    Patent number: 4521334
    Abstract: Peptide fragments of streptococcal M protein named CB3, CB4, and CB5 and related synthetic peptides have been identified. When linked to a protein carrier which is polylysine the conjugates of CB3, CB4, CB5, and S-CB3 are capable of evoking type specific opsonic antibodies against streptococci.
    Type: Grant
    Filed: June 10, 1983
    Date of Patent: June 4, 1985
    Assignee: The University of Tennesse Research Corporation
    Inventor: Edwin H. Beachey
  • Synthetic peptides corresponding to antigenic determinants of the M protein of Streptococcus pyogenes
    Patent number: 4454121
    Abstract: Synthetic peptides corresponding to antigenic determinants of the M protein of streptococcus pyogenes are disclosed. These peptides are useful for vaccination against streptococcus pyogenes bacteria.
    Type: Grant
    Filed: July 27, 1982
    Date of Patent: June 12, 1984
    Assignee: The University of Tennessee Research Corporation
    Inventor: Edwin H. Beachey
  • Conjugate of streptococcal M protein peptide vaccine
    Patent number: 4284537
    Abstract: Certain peptide fragments of streptococcal M protein named CB6 and CB7 have been linked to a protein carrier which is polylysine. The conjugate has proved immunogenic in rabbits producing protective antibodies against the whole group A streptococcus.
    Type: Grant
    Filed: July 3, 1980
    Date of Patent: August 18, 1981
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Edwin H. Beachey