Patents by Inventor Edwin Maria-Selvaraj

Edwin Maria-Selvaraj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11246551
    Abstract: The present disclosure relates to a system, method, and computer program product for computer-aided detection (CAD) of suspicious lesions in digital breast specimen radiographs, wherein single-view feature vectors from a first digital radiograph of the breast specimen are processed in a classification algorithm along with information computed from a plurality of related digital specimen radiographs to assign an overall probability of suspiciousness to potentially suspicious lesions in the first digital breast specimen radiography. In one embodiment, a greater probability of suspiciousness is determined where there are similar corresponding lesions in the first digital breast specimen radiography and in an alternate digital breast specimen radiography view of the same breast specimen.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: February 15, 2022
    Assignee: KUB Technologies, Inc.
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj
  • Patent number: 11207036
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and an optical camera for the production of organic and non-organic images. The computing device receives data including video data from an optical camera, a laser detector, an infrared detector, an ultrasonic detector, or a weight scale or pressure sensor, and determines automatically, based on the resultant data, if a sample/specimen has been left in the sample chamber. In particular, the disclosure relates to a system and method with corresponding apparatus for automatic detection if a sample/specimen has been left in the sample chamber without having to open the chamber door.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: December 28, 2021
    Assignee: KUB Technologies, Inc.
    Inventors: Vikram Butani, Yan Chen, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Roberto Velasco
  • Patent number: 11039803
    Abstract: It would be advantageous with the close quarters in breast procedure rooms to create a system and method incorporating 2 modalities utilized in breast intervention procedures for the diagnosis and verification for breast cancer. Systems for specimen radiography assist radiologists and surgeons in the detection and classification of abnormal lesions in medical images gleaned from breast biopsies/lumpectomies and a Gamma or other probe system with a sensor to detect radioactive, metallic/magnet, or RFID waves to help locate a lump or abnormality which were placed by an Interventional Radiologist. With the utilization of a dual modality machine, the physician can detect the abnormalities, remove the abnormalities, and verify that they have achieved a clean margin, currently 1 mm, from the cancerous or abnormal tissues. Currently it is believed that there is not a system or method utilizing both a Gamma or other probe and Radiography in a cabinet system.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: June 22, 2021
    Assignee: Kub Technologies, Inc.
    Inventors: Vikram Butani, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, John Pizzonia, Peter Yasutake
  • Publication number: 20210164922
    Abstract: A cabinet x-ray includes an x-ray tube, an x-ray detector, and a near-infrared optical system mounted onto the cabinet or positioned within the cabinet, for the production of organic and non-organic images. The computing device receives video data from the near-infrared optical system and determines, based on the video data an optical image displaying the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the present disclosure also relates to a system and method with corresponding apparatus for capturing a near-infrared image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images utilizing near-infrared (NIR) fluorescence for sentinel lymph node (SLN) mapping in breast cancer patients to improve the Sentinel Lymph Node identification and procedure.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 3, 2021
    Applicant: KUB Technologies Inc.
    Inventors: Vikram Butani, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Peter Yasutake
  • Patent number: 11020066
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating a stationary x-ray source array, and an x-ray detector, for the production of organic and non-organic images. Stationary x-ray digital cabinet tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object. In the preferred embodiment, the x-ray source or sources are statically affixed in a range from about 350° to and including about 10°.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: June 1, 2021
    Assignee: Kub Technologies, Inc.
    Inventors: Vikram Butani, Yan Chen, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Roberto Velasco, Peter Yasutake
  • Patent number: 10921265
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a near-infrared optical system mounted onto the cabinet or positioned within the cabinet, for the production of organic and non-organic images. The computing device receives video data from the near-infrared optical system and determines, based on the video data an optical image displaying the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the present disclosure also relates to a system and method with corresponding apparatus for capturing a near-infrared image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images utilizing near-infrared (NIR) fluorescence for sentinel lymph node (SLN) mapping in breast cancer patients to improve the Sentinel Lymph Node identification and procedure.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: February 16, 2021
    Assignee: KUB Techologles Inc.
    Inventors: Vikram Butani, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Peter Yasutake
  • Patent number: 10837921
    Abstract: The aspects of the present disclosure are directed to a method and system for producing tomosynthesis images of a breast specimen with the capability of attaining images with geometric magnification. In one embodiment, an x-ray source delivers x-rays through a specimen of excised tissue and forms an image at a digital x-ray detector with the resultant image enlarging as the specimen is moved closer to the x-ray source. Multiple x-ray images are taken as the x-ray source moves relative to the stationary breast specimen. The source may travel substantially along a path while the detector remains stationary throughout and the source remains substantially equidistant from the specimen platform. The set of x-ray image data taken at the different points are combined to form a tomosynthesis image that can be viewed in different formats, alone or as an adjunct to conventional specimen radiography.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: November 17, 2020
    Assignee: Kub Technologies, Inc.
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj, Roberto Velasco
  • Publication number: 20200340931
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a near-infrared optical system mounted onto the cabinet or positioned within the cabinet, for the production of organic and non-organic images. The computing device receives video data from the near-infrared optical system and determines, based on the video data an optical image displaying the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the present disclosure also relates to a system and method with corresponding apparatus for capturing a near-infrared image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images utilizing near-infrared (NIR) fluorescence for sentinel lymph node (SLN) mapping in breast cancer patients to improve the Sentinel Lymph Node identification and procedure.
    Type: Application
    Filed: April 23, 2020
    Publication date: October 29, 2020
    Applicant: KUB Technologies Inc.
    Inventors: Vikram Butani, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Peter Yasutake
  • Publication number: 20200191730
    Abstract: The aspects of the present disclosure are directed to a method and system for producing tomosynthesis images of a breast specimen with the capability of attaining images with geometric magnification. In one embodiment, an x-ray source delivers x-rays through a specimen of excised tissue and forms an image at a digital x-ray detector with the resultant image enlarging as the specimen is moved closer to the x-ray source. Multiple x-ray images are taken as the x-ray source moves relative to the stationary breast specimen. The source may travel substantially along a path while the detector remains stationary throughout and the source remains substantially equidistant from the specimen platform. The set of x-ray image data taken at the different points are combined to form a tomosynthesis image that can be viewed in different formats, alone or as an adjunct to conventional specimen radiography.
    Type: Application
    Filed: November 21, 2019
    Publication date: June 18, 2020
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj, Roberto Velasco
  • Publication number: 20200182807
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating a stationary x-ray source array, and an x-ray detector, for the production of organic and non-organic images. Stationary x-ray digital cabinet tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object. In the preferred embodiment, the x-ray source or sources are statically affixed in a range from about 350° to and including about 10°.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 11, 2020
    Inventors: Vikram Butani, Yan Chen, Chester Lowe, Vignesh Mandala-Bhoopathy, Edwin Maria-Selvaraj, Roberto Velasco, Peter Yasutake
  • Patent number: 10598610
    Abstract: An X-ray system for analyzing materials includes an X-ray source, an X-ray detector and a sample platform, and a controller configured to generate a radiograph of material on the sample platform by selectively energizing the X-ray source to emit X-rays through the material to the X-ray detector along a scanned length of the material, calculate a plurality of measured density values along the scanned length of the material, calculate a plurality of model density values of the material from one or more of settings of the X-ray system, characteristics of the material along the scanned length of the material, and a longitudinal density variation for a particular application, compute a difference between the measured density values and the model density values and determine if the longitudinal density variation has been exceeded, and provide an alert as to whether the longitudinal density variation has been exceeded.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: March 24, 2020
    Assignee: KUB Technologies, Inc
    Inventors: Vikram Butani, Yan Chen, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Roberto Velasco, Peter Yasutake
  • Patent number: 10488351
    Abstract: The aspects of the present disclosure are directed to a method and system for producing tomosynthesis images of a breast specimen with the capability of attaining images with geometric magnification. In one embodiment, an x-ray source delivers x-rays through a specimen of excised tissue and forms an image at a digital x-ray detector with the resultant image enlarging as the specimen is moved closer to the x-ray source. Multiple x-ray images are taken as the x-ray source moves relative to the stationary breast specimen. The source may travel substantially along a path while the detector remains stationary throughout and the source remains substantially equidistant from the specimen platform. The set of x-ray image data taken at the different points are combined to form a tomosynthesis image that can be viewed in different formats, alone or as an adjunct to conventional specimen radiography.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: November 26, 2019
    Assignee: KUB TECHNOLOGIES, INC.
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj, Roberto Velasco
  • Publication number: 20190053771
    Abstract: The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and an optical camera for the production of organic and non-organic images. The computing device receives data including video data from an optical camera, a laser detector, an infrared detector, an ultrasonic detector, or a weight scale or pressure sensor, and determines automatically, based on the resultant data, if a sample/specimen has been left in the sample chamber. In particular, the disclosure relates to a system and method with corresponding apparatus for automatic detection if a sample/specimen has been left in the sample chamber without having to open the chamber door.
    Type: Application
    Filed: August 16, 2018
    Publication date: February 21, 2019
    Inventors: Vikram Butani, Yan Chen, Chester Lowe, Vignesh Mandalapa-Bhoopathy, Edwin Maria-Selvaraj, Roberto Velasco
  • Publication number: 20180078231
    Abstract: The present disclosure relates to a system, method, and computer program product for computer-aided detection (CAD) of suspicious lesions in digital breast specimen radiographs, wherein single-view feature vectors from a first digital radiograph of the breast specimen are processed in a classification algorithm along with information computed from a plurality of related digital specimen radiographs to assign an overall probability of suspiciousness to potentially suspicious lesions in the first digital breast specimen radiography. In one embodiment, a greater probability of suspiciousness is determined where there are similar corresponding lesions in the first digital breast specimen radiography and in an alternate digital breast specimen radiography view of the same breast specimen.
    Type: Application
    Filed: September 20, 2017
    Publication date: March 22, 2018
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj
  • Publication number: 20180067061
    Abstract: The aspects of the present disclosure are directed to a method and system for producing tomosynthesis images of a breast specimen with the capability of attaining images with geometric magnification. In one embodiment, an x-ray source delivers x-rays through a specimen of excised tissue and forms an image at a digital x-ray detector with the resultant image enlarging as the specimen is moved closer to the x-ray source. Multiple x-ray images are taken as the x-ray source moves relative to the stationary breast specimen. In the preferred embodiment, the x-ray source moves in a range from about 350° to and including about 10°. The source may travel substantially along a path that generally defines an arc, or linearly, while the detector remains stationary throughout and the source remains substantially equidistant from the specimen platform.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 8, 2018
    Inventors: Vikram Butani, Yan Chen, Timothy Ely, Chester Lowe, Edwin Maria-Selvaraj, Roberto Velasco