Patents by Inventor Edwin R. Thompson

Edwin R. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10959958
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: March 30, 2021
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Patent number: 10792254
    Abstract: The present disclosure relates to an oral, extended release pill containing a drug which is homogenously spread throughout a matrix. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and can be abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: October 6, 2020
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 10639281
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: May 5, 2020
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20190209481
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: December 5, 2018
    Publication date: July 11, 2019
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 10195153
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: February 5, 2019
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 10172797
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 8, 2019
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20170340574
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.
    Type: Application
    Filed: June 13, 2017
    Publication date: November 30, 2017
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Patent number: 9707184
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: July 18, 2017
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Publication number: 20170020822
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.
    Type: Application
    Filed: June 7, 2016
    Publication date: January 26, 2017
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Publication number: 20170007544
    Abstract: The present disclosure relates to an oral, extended release pill containing a drug which is homogenously spread throughout a matrix. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and can be abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 12, 2017
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 9492444
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: November 15, 2016
    Assignee: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20160317448
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: December 17, 2014
    Publication date: November 3, 2016
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20160199369
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: August 12, 2014
    Publication date: July 14, 2016
    Applicants: Pharmaceutical Manufacturing Research Services, Inc., Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20160106737
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.
    Type: Application
    Filed: October 20, 2015
    Publication date: April 21, 2016
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Publication number: 20160015650
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 21, 2016
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
  • Publication number: 20150165041
    Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 18, 2015
    Applicant: Pharmaceutical Manufacturing Research Services, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Publication number: 20150057304
    Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
    Type: Application
    Filed: August 12, 2014
    Publication date: February 26, 2015
    Applicant: Pharmaceutical Manufacturing Research Service, Inc.
    Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
  • Patent number: 4395819
    Abstract: A pre-closed slide mount has two sides secured together defining an internal pocket to retain a film transparency T inserted edgewise through an entranceway in one edge of the slide mount, which has a window for viewing. A retraction clearance slot at one end of the entranceway may provide clearance for the bowed filmstrip pusher S to be retracted while lateral movement 38 of the slide mount commences. The transparency T is cut from the leading end of the filmstrip S while said end is entirely outside of the entranceway into the slide mount. A reciprocatable pawl and its associated reciprocating drive means produces a forward stroke F of the filmstrip S equal to the length of the transparency T plus an additional extent of forward travel sufficient for pushing the transparency T completely into said pocket. Then, the filmstrip is retracted R by a distance sufficient for completely removing the film strip from the loaded slide mount.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: August 2, 1983
    Assignee: Forox Corporation
    Inventor: Edwin R. Thompson
  • Patent number: 4342147
    Abstract: An improved pre-closed slide mount is described having two sides or masks which are secured together for defining an internal pocket to retain a film transparency which is inserted edgewise through an opening or entranceway in one edge of the mount and defining a window for viewing the transparency in the mount. An elevated border region formed in one mask of the mount extends transversely across the entranceway and has a sloping outer surface to provide a funnel for directing a transparency into the entranceway, and this border region has laterally sloping ends which define two spaced valleys for receiving the outer edges of a longitudinally bowed film strip serving as pusher for the inserted transparency. The outer edges of the valleys are defined by lateral transparency guides. The border region of the other mask forms an elevated roof over the elevated border region with inverted steps over the laterally sloping end portions of the border region.
    Type: Grant
    Filed: July 24, 1980
    Date of Patent: August 3, 1982
    Assignee: Forox Corporation
    Inventor: Edwin R. Thompson
  • Patent number: 4250641
    Abstract: An improved pre-closed slide mount is described having two sides or masks which are secured together for defining an internal pocket to retain a film transparency which is inserted edgewise through an opening or entranceway in one edge of the mount and defining a window for viewing the transparency in the mount. An elevated border region formed in one mask of the mount extends transversely across the entranceway and has a sloping outer surface to provide a funnel for directing a transparency into the entranceway, and this border region has laterally sloping ends which define two spaced valleys the purpose of which is to receive the outer edges of a longitudinally bowed film strip serving as pusher for the inserted transparency. The outer edges of the valleys are defined by lateral transparency guides. The border region of the other mask forms an elevated roof over the elevated border region with inverted steps over the laterally sloping end portions of the border region.
    Type: Grant
    Filed: October 18, 1978
    Date of Patent: February 17, 1981
    Assignee: Forox Corporation
    Inventor: Edwin R. Thompson