Patents by Inventor Edwin R. Thompson
Edwin R. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10959958Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.Type: GrantFiled: June 7, 2016Date of Patent: March 30, 2021Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Patent number: 10792254Abstract: The present disclosure relates to an oral, extended release pill containing a drug which is homogenously spread throughout a matrix. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and can be abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: GrantFiled: September 20, 2016Date of Patent: October 6, 2020Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Patent number: 10639281Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: GrantFiled: December 5, 2018Date of Patent: May 5, 2020Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20190209481Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: December 5, 2018Publication date: July 11, 2019Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Patent number: 10195153Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: GrantFiled: August 12, 2014Date of Patent: February 5, 2019Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Patent number: 10172797Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: GrantFiled: December 17, 2014Date of Patent: January 8, 2019Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20170340574Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.Type: ApplicationFiled: June 13, 2017Publication date: November 30, 2017Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Patent number: 9707184Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.Type: GrantFiled: July 7, 2015Date of Patent: July 18, 2017Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Publication number: 20170020822Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.Type: ApplicationFiled: June 7, 2016Publication date: January 26, 2017Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Publication number: 20170007544Abstract: The present disclosure relates to an oral, extended release pill containing a drug which is homogenously spread throughout a matrix. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and can be abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: September 20, 2016Publication date: January 12, 2017Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Patent number: 9492444Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: GrantFiled: December 17, 2014Date of Patent: November 15, 2016Assignee: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20160317448Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: December 17, 2014Publication date: November 3, 2016Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20160199369Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: August 12, 2014Publication date: July 14, 2016Applicants: Pharmaceutical Manufacturing Research Services, Inc., Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20160106737Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.Type: ApplicationFiled: October 20, 2015Publication date: April 21, 2016Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Publication number: 20160015650Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.Type: ApplicationFiled: July 7, 2015Publication date: January 21, 2016Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny, Matthew N. Hart
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Publication number: 20150165041Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: December 17, 2014Publication date: June 18, 2015Applicant: Pharmaceutical Manufacturing Research Services, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Publication number: 20150057304Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.Type: ApplicationFiled: August 12, 2014Publication date: February 26, 2015Applicant: Pharmaceutical Manufacturing Research Service, Inc.Inventors: Edwin R. Thompson, Eric R. Thompson, Nicholas R. Myslinski, Steven F. Kemeny
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Patent number: 4395819Abstract: A pre-closed slide mount has two sides secured together defining an internal pocket to retain a film transparency T inserted edgewise through an entranceway in one edge of the slide mount, which has a window for viewing. A retraction clearance slot at one end of the entranceway may provide clearance for the bowed filmstrip pusher S to be retracted while lateral movement 38 of the slide mount commences. The transparency T is cut from the leading end of the filmstrip S while said end is entirely outside of the entranceway into the slide mount. A reciprocatable pawl and its associated reciprocating drive means produces a forward stroke F of the filmstrip S equal to the length of the transparency T plus an additional extent of forward travel sufficient for pushing the transparency T completely into said pocket. Then, the filmstrip is retracted R by a distance sufficient for completely removing the film strip from the loaded slide mount.Type: GrantFiled: May 10, 1982Date of Patent: August 2, 1983Assignee: Forox CorporationInventor: Edwin R. Thompson
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Patent number: 4342147Abstract: An improved pre-closed slide mount is described having two sides or masks which are secured together for defining an internal pocket to retain a film transparency which is inserted edgewise through an opening or entranceway in one edge of the mount and defining a window for viewing the transparency in the mount. An elevated border region formed in one mask of the mount extends transversely across the entranceway and has a sloping outer surface to provide a funnel for directing a transparency into the entranceway, and this border region has laterally sloping ends which define two spaced valleys for receiving the outer edges of a longitudinally bowed film strip serving as pusher for the inserted transparency. The outer edges of the valleys are defined by lateral transparency guides. The border region of the other mask forms an elevated roof over the elevated border region with inverted steps over the laterally sloping end portions of the border region.Type: GrantFiled: July 24, 1980Date of Patent: August 3, 1982Assignee: Forox CorporationInventor: Edwin R. Thompson
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Patent number: 4250641Abstract: An improved pre-closed slide mount is described having two sides or masks which are secured together for defining an internal pocket to retain a film transparency which is inserted edgewise through an opening or entranceway in one edge of the mount and defining a window for viewing the transparency in the mount. An elevated border region formed in one mask of the mount extends transversely across the entranceway and has a sloping outer surface to provide a funnel for directing a transparency into the entranceway, and this border region has laterally sloping ends which define two spaced valleys the purpose of which is to receive the outer edges of a longitudinally bowed film strip serving as pusher for the inserted transparency. The outer edges of the valleys are defined by lateral transparency guides. The border region of the other mask forms an elevated roof over the elevated border region with inverted steps over the laterally sloping end portions of the border region.Type: GrantFiled: October 18, 1978Date of Patent: February 17, 1981Assignee: Forox CorporationInventor: Edwin R. Thompson