Abstract: Compounds of general formula I, ##STR1## wherein R.sup.1 represents hydrogen or alkyl C.sub.1-3,R.sup.2 represents hydrogen or alkyl C.sub.1-6,n and m are integers from 1 to 3, provided that n+m=4, andone of X and Y represents CH.sub.2 and the other represents CHR.sup.3, C.dbd.O, C.dbd.CHR.sup.4 or C.dbd.NR.sup.5, in whichR.sup.3, R.sup.4 and R.sup.5 are as defined in the specification,and their saltsare useful as pharmaceuticals, in particular as central muscarinic acetylcholine receptors. The compounds are therefore useful in the treatment of diseases such as presenile and senile dementia, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania and Tourette Syndrome, and also as analgesic agents for use in the treatment of severe painful conditions such as rheumatism, arthritis, and terminal illness.

Abstract: Compounds of general formula I, ##STR1## wherein: A represents (CH.sub.2).sub.m optionally substituted by R.sub.3,B represents (CH.sub.2).sub.n optionally substituted by R.sub.4,R.sub.1 represents hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1-6 alkenyl or C.sub.1-6 alkynyl,R.sub.2 represents hydrogen, C.sub.1 -C.sub.6 alkyl or COOR.sub.5, in which R.sub.5 represents C.sub.1 -C.sub.6 alkyl,R.sub.3 and R.sub.4 independently represent hydrogen or C.sub.1 -C.sub.6 alkyl,in addition, any two of R.sub.2, R.sub.3 and R.sub.4 may together form a C.sub.1-3 alkylene chain,n and m independently represent an integer from 1-3 inclusive,Y represents O or S,and pharmaceutically acceptable acid addition salts thereof are useful as pharmaceuticals, in particular as central muscarinic acetylcholine receptor agonists. The compounds are therefore useful in the treatment of diseases such as presenile and senile dementia, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania and Tourette Syndrome.

Abstract: 7-[3-[(3,4-dihydroxyphenethyl)amino]-2-hydroxypropoxy]-flavone hydrobromide, and related flavonoids are disclosed to inhibit leukotrienes and 5-lipoxygenase; preferred compounds also inhibit rat anaphylaxis.

Abstract: Compounds such as 6-[3-(cyclopropylamino)-2-hydroxypropoxy]aurone hydrochloride showing inhibitory activity against LTC.sub.4 -induced contraction of guinea pig ileum are useful as inhibitors of allergic reactions.

Abstract: Ester derivatives of N-substituted and N,N-disubstituted aminopropanoloxy flavones in which the aminopropanoloxy side chain is inserted at either the 5-, 6-, 7- or 8-position of the flavone nucleus, and N-substituted and N,N-disubstituted aminopropanoloxy flavones in which the aminopropanoloxy side chain is inserted at the 8-position of the flavone nucleus; useful as anti-dysrhythmic agents.

Abstract: Chromone derivatives such as 7-(3-n-propylamino-2-hydroxypropoxy)-2,3-diphenylchromones which are useful as pharmaceuticals having antihypertensive properties.

Abstract: Chromone derivatives such as 7-(3-n-propylamino-2-hydroxypropoxy)-2-phenyl-chromones which are useful as pharmaceuticals having antihypertensive properties.

Abstract: Chromone derivatives such as 7-(3-amino-2-hydroxypropoxy)-3-phenylchromones which are useful for preparing other chemical compounds and for pharmaceutical uses such as antihypertensive and anti-inflammatory agents.

Abstract: Chromone derivatives such as 6 or 7-(3-amino-2-hydroxypropoxy)-2-phenylchromones, -3-phenylchromones or -2,3-diphenylchromones which are useful as antihypertensive agents.