Patents by Inventor Edwin Vedejs

Edwin Vedejs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-heteroarenesulfonyl-protected amino acid reagents for peptide synthesis
    Patent number: 5900427
    Abstract: This invention relates to the use of heteroarenesulfonyl groups as protecting groups for amino groups, particularly the amino groups of amino acids, and specifically to nitrogen-protected (N-protected) amino acid reagents, which are particularly well-suited for use in peptide syntheses. In particular, the N-protected amino acid reagent is an N-heteroarenesulfonyl-protected amino acid halide. The heteroarenesulfonyl protecting groups are readily removed under relatively mild conditions.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: May 4, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Edwin Vedejs, Jiabing Wang, Shouzhong Lin, Artis Klapars
  • Reagents for enantioselective acylation and related reactions
    Patent number: 5646287
    Abstract: The invention provides a method for synthesizing chiral compounds utilizing novel catalysts which are enantioselective electrophiles via kinetic resolution. The method includes treating a racemic mixture with a reagent which is a chiral DMAP derivative, a chloroformate, a trialkylamine and a Lewis acid to preferentially form a product of one of the enantiomer pair of the mixture. The invention also provides a method for resolving racemic mixture via parallel kinetic resolution.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: July 8, 1997
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Edwin Vedejs, Xinhai Chen