Patents by Inventor Edwin Wang
Edwin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180304040Abstract: In some examples, a catheter includes a catheter body including an outer jacket and an inner liner. The inner liner may include a proximal section including a proximal end of the inner liner and a distal section including a distal end of the inner liner. The distal section may include an inner liner defining a plurality of cuts. Each cut may extend at least partially through the liner wall. The one or more cuts defined in the liner wall of the distal section of the inner liner may increase a bending flexibility of the distal section relative to the proximal section of the inner liner, while maintaining a suitable tensile strength of the distal section.Type: ApplicationFiled: April 20, 2017Publication date: October 25, 2018Inventors: Ujwal Jalgaonkar, Edwin Wang, David Marchesiello
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Publication number: 20180250498Abstract: In some examples, a catheter includes an elongated body comprising proximal and distal portions. The distal portion of the elongated body comprises an inner liner that includes a proximal liner section and a distal liner section that include different materials, and an outer jacket positioned over the inner liner. The distal liner section has a first hardness and the proximal liner section has a second hardness, where the first hardness is less than the second hardness.Type: ApplicationFiled: March 2, 2017Publication date: September 6, 2018Inventors: George Stern, Edwin Bon, Edwin Wang, Ujwal Jalgaonkar, Peter Skujins
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Patent number: 9855400Abstract: A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.Type: GrantFiled: June 3, 2009Date of Patent: January 2, 2018Assignee: ABBOTT CARDIOVASCULAR SYSTEMS, INC.Inventors: Jeong S. Lee, Edwin Wang, Roseminda J. White
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Publication number: 20170281915Abstract: In some examples, a catheter may include a catheter body, a first expandable member, and a second expandable member. The catheter body may define a first lumen, a second lumen, a delivery port, and a surface extending from the delivery port into the first lumen. The first lumen may define a first central longitudinal axis. The second lumen may define a second central longitudinal axis spaced from the first central longitudinal axis in a direction orthogonal to the second central longitudinal axis. The delivery port may be in fluid communication with the first lumen. The surface extending from the delivery port into the first surface may be oriented at an obtuse or acute angle relative to the first central longitudinal axis.Type: ApplicationFiled: March 31, 2016Publication date: October 5, 2017Inventors: Ujwal Jalgaonkar, Edwin Wang, Edwin Bon
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Publication number: 20170106166Abstract: In some examples, a catheter body includes an outer jacket positioned over a structural support member. A proximal portion of the structural support member comprises a straight or tapered polymer hypotube and a distal portion of the structural support member comprises a distal support member that is more flexible than the polymer hypotube. In some examples, the polymer hypotube defines one or more openings, through which an adhesive may be introduced between the polymer hypotube and an inner liner of the catheter body.Type: ApplicationFiled: October 16, 2015Publication date: April 20, 2017Inventors: Edwin Wang, Komonn Lim, Bryant Pham
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Publication number: 20170043060Abstract: A catheter may include a hypotube defining an inner circumferential surface, an outer circumferential surface, and an end. The hypotube may include a metal or alloy. The catheter also may include an inner liner attached to the inner circumferential surface of the hypotube and extending beyond the end of the hypotube, and the inner liner may include a fluoropolymer. The catheter further may include a hub and a single bonding layer attached to the outer circumferential surface of the hypotube and bonded to the hub. The single bonding layer may include a polyamide, a polyether-co-polyamide, or polyurethane and is the only layer between the outer circumferential surface of the hypotube and the hub.Type: ApplicationFiled: August 12, 2015Publication date: February 16, 2017Inventors: Edwin Wang, Komonn Lim
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Patent number: 9463105Abstract: Stent delivery systems and methods of use are provided. The systems can include a catheter, a core member, and engagement member, and a stent. The catheter can have a inner wall. The core member can extend within the catheter and having a distal segment. The engagement member can be attached to the distal segment. Further, the stent can be positioned within the catheter and extend over the engagement member. The stent can have an axial length that is greater than an axial length of the engagement member. The engagement member can have an expanded state in which the engagement member presses the stent against the catheter inner wall for engaging the stent to move the stent along with the core member relative to the catheter.Type: GrantFiled: March 14, 2013Date of Patent: October 11, 2016Assignee: Covidien LPInventors: Lawrence Farhat, Edwin Wang, David Franco
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Patent number: 9364635Abstract: A catheter system is provided. The system includes a catheter having an elongated flexible body and one or more electroactive polymer actuators disposed along the elongated flexible body. The electroactive polymer actuators are adapted to cause a change in configuration of the elongated flexible body. The system also includes a controller adapted to transmit the control signal to the electroactive polymer actuators. The controller includes a memory storing a plurality of control signals corresponding to a plurality of predetermined configurations of the catheter and a user-interface coupled to the memory. The user-interface is configured to select one or more configurations from the plurality of predetermined configurations in response to user input.Type: GrantFiled: September 20, 2013Date of Patent: June 14, 2016Assignee: Covidien LPInventors: Edwin Wang, Christopher Folk
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Publication number: 20150088060Abstract: A catheter system is provided. The system includes a catheter having an elongated flexible body and one or more electroactive polymer actuators disposed along the elongated flexible body. The electroactive polymer actuators are adapted to cause a change in configuration of the elongated flexible body. The system also includes a controller adapted to transmit the control signal to the electroactive polymer actuators. The controller includes a memory storing a plurality of control signals corresponding to a plurality of predetermined configurations of the catheter and a user-interface coupled to the memory. The user-interface is configured to select one or more configurations from the plurality of predetermined configurations in response to user input.Type: ApplicationFiled: September 20, 2013Publication date: March 26, 2015Applicant: Covidien LPInventors: Edwin Wang, Christopher Folk
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Patent number: 8940010Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.Type: GrantFiled: March 1, 2013Date of Patent: January 27, 2015Assignee: Abbott Cardiovascular Systems Inc.Inventors: Jeong S. Lee, Edwin Wang
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Publication number: 20140349878Abstract: Cancer marker sets consisting of particular genes differentially expressed in tumours provide improved accuracy of predicting effectiveness of paclitaxel or paclitaxel-like drug treatment against a cancer. These sets are further useful for screening drug candidates for paclitaxel-like cancer treatment activity. The cancer marker sets may be used in a clinical setting to provide information about the likelihood that a cancer patient would or would not respond to paclitaxel or paclitaxel-like drug treatment.Type: ApplicationFiled: November 27, 2012Publication date: November 27, 2014Applicant: NATIONAL RESEARCH COUNCIL OF CANADAInventors: Edwin Wang, Jie Li, Maureen O'Connor-McCourt, Enrico Purisima
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Patent number: 8888805Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.Type: GrantFiled: March 1, 2013Date of Patent: November 18, 2014Assignee: Abbott Cardiovascular Systems Inc.Inventors: Jeong S. Lee, Edwin Wang
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Publication number: 20140277361Abstract: Stent delivery systems and methods of use are provided. The systems can include a catheter, a core member, and engagement member, and a stent. The catheter can have a inner wall. The core member can extend within the catheter and having a distal segment. The engagement member can be attached to the distal segment. Further, the stent can be positioned within the catheter and extend over the engagement member. The stent can have an axial length that is greater than an axial length of the engagement member. The engagement member can have an expanded state in which the engagement member presses the stent against the catheter inner wall for engaging the stent to move the stent along with the core member relative to the catheter.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: COVIDIEN LPInventors: Lawrence FARHAT, Edwin WANG, David FRANCO
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Publication number: 20140011701Abstract: Prostate cancer marker sets consisting of particular genes differentially expressed in prostate tumours provide improved accuracy of prostate cancer prognosis. The prostate cancer marker sets of the present invention, one of which consists of 30 genes related to apoptosis, one of which consists of 22 genes related to cell cycle and one of which consists of 30 genes related to response to external stimulus, may be used in a clinical setting to provide information about the likelihood of a prostate cancer patient to survive without treatment (i.e. whether the prostate tumour is “good” or “bad”).Type: ApplicationFiled: February 16, 2012Publication date: January 9, 2014Applicant: National Research Council of CanadaInventors: Edwin Wang, Jie Li, Maureen O'Connor-McCourt
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Patent number: 8388640Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.Type: GrantFiled: December 12, 2011Date of Patent: March 5, 2013Assignee: Abbott Cardiovascular Systems Inc.Inventors: Jeong S. Lee, Edwin Wang
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Patent number: 8221444Abstract: An elongated balloon catheter having a distal tip member on the distal end of the catheter and having a sleeve surrounding and secured at least to the proximal end of the distal tip member.Type: GrantFiled: November 14, 2008Date of Patent: July 17, 2012Assignee: Abbott Cardiovascular Systems Inc.Inventors: Edwin Wang, Roseminda J. White, Jeong S. Lee, Tim Kitchen
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Publication number: 20120083732Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.Type: ApplicationFiled: December 12, 2011Publication date: April 5, 2012Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Jeong S. Lee, Edwin Wang
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Publication number: 20120040863Abstract: A process to identify tumour characteristics involves obtaining three different marker sets each predictive of a characteristic of interest, obtaining a sample gene expression signals from tumour cells, adding a reporter to affect a change in the sample permitting assessment of a gene expression signal of interest in the tumour, combining the gene expression signals with the reporter, correlating the extracted gene expression signals to the three different marker sets, assigning a designation to the extracted gene expression signals according to the following rankings: if the correlation of all three predictive gene expression signal sets predict it to have characteristics of concern, it is designated a bad tumour; if the correlation of all three predictive gene expression signal sets predict it to lack characteristics of concern it is designated a good tumour; and, if the correlation of all three predictive gene expression signal sets do not provide the same predicted clinical outcome, the tumour is designatType: ApplicationFiled: April 16, 2010Publication date: February 16, 2012Inventors: Edwin Wang, Jie Li, Yinghai Deng, Anne E. G. Lenferink, Maureen D. O'Connor-McCourt, Enrico Purisma
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Patent number: 8083726Abstract: A method including combining a cellular component with a viability enhancer material wherein the combination will inhibit an interaction between the cellular component and a delivery device; and delivering the cellular component through the delivery device. An apparatus including a delivery cannula having dimensions suitable for percutaneous delivery and a lumen therethrough, wherein a portion of a luminal surface of the cannula includes a coating that is amenable to a cellular component delivered through the delivery cannula. A method including percutaneously introducing a delivery cannula into a blood vessel; advancing a distal portion of the delivery cannula to a treatment site; and delivering a cellular component through a lumen of the delivery cannula, wherein a portion of a luminal surface of the cannula includes a coating that is amenable to a cellular component delivered through the delivery cannula.Type: GrantFiled: September 30, 2005Date of Patent: December 27, 2011Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Edwin Wang
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Patent number: 8075583Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.Type: GrantFiled: September 28, 2005Date of Patent: December 13, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Jeong S. Lee, Edwin Wang