Patents by Inventor Edze Tijsma

Edze Tijsma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Injectable formulation capable of forming a drug-releasing device
    Publication number: 20070110788
    Abstract: The present invention relates to an injectable formulation comprising an active substance and capable of releasing a therapeutically effective amount of said active substance, wherein said formulation is made of a formable material designed to adapt and conform to the shape of at least a part of a cavity of an individual's skull when engaged therewith, and wherein said material is hardenable upon engagement with at least a part of said cavity to provide said device with a permanent shape
    Type: Application
    Filed: November 14, 2005
    Publication date: May 17, 2007
    Inventors: James Hissong, Edze Tijsma, Maria Nieves Lopez
  • Drug-releasing sinus stent
    Publication number: 20070014830
    Abstract: The present invention relates to a stent, adapted for deployment in a nasal sinus, comprising a matrix metalloproteinase-inhibiting substance and capable of locally releasing in a controlled manner a therapeutically effective amount of said matrix metalloproteinase-inhibiting substance. The invention further relates to a method for treatment of a diseased or damaged sinus mucosal tissue in a patient, said method comprising introducing into the sinus of said patient a stent comprising a matrix metalloproteinase-inhibiting substance.
    Type: Application
    Filed: June 8, 2005
    Publication date: January 18, 2007
    Inventors: Edze Tijsma, Claus Bachert, James Hissong, Jean-Baptiste Watelet
  • Use of biocompatible in-situ matrices for delivery of therapeutic cells to the heart
    Publication number: 20060253068
    Abstract: The present invention provides novel methods and systems for delivering therapeutic cells to the heart of a subject.
    Type: Application
    Filed: April 20, 2005
    Publication date: November 9, 2006
    Inventors: Paul van Bilsen, Edze Tijsma
  • Angiotensin-(1-7) eluting polymer-coated medical device to reduce restenosis and improve endothelial cell function
    Publication number: 20060088572
    Abstract: Medical devices with polymer coatings designed to control the release of angiotensin-(1-7) receptor agonists from medical devices are disclosed. The present application also discloses providing vascular stents with angiotensin-(1-7) receptor agonist-containing controlled-release coatings. Methods for treating or inhibiting post-stent implantation restenosis as well as improving vascular endothelial function in patients are also provided.
    Type: Application
    Filed: October 21, 2005
    Publication date: April 27, 2006
    Applicant: Medtronic, Inc.
    Inventors: Edze Tijsma, Anita Driessen-Levels, Marc Hendriks
  • Therapeutic blood vessel treatment
    Publication number: 20060004441
    Abstract: A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a delivery vehicle in a localized, time-release regimen, to treat and reduce the severity of the aneurysm. The delivery vehicle is provided in conjunction with the placement of an excluding device, such as a stent graft.
    Type: Application
    Filed: August 3, 2004
    Publication date: January 5, 2006
    Applicant: Medtronic Vascular, Inc.
    Inventors: Edze Tijsma, Mirian Gillissen, Brian Kwitkin