Patents by Inventor Efim Ilya Golub

Efim Ilya Golub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030208053
    Abstract: In accordance with the objects outlined above, the present invention provides methods of diagnosing individuals at risk for a disease state which results in aberrant Rad51 loci. The methods comprise determining the distribution of Rad51 foci in a first tissue type of a first individual, and then comparing the distribution to the distribution of Rad51 foci from a second normal tissue type from the first individual or a second unaffected individual. A difference in the distributions indicates that the first individual is at risk for a disease state which results in aberrant Rad51 loci. Preferred disease states include cancer and disease states associated with apoptosis.
    Type: Application
    Filed: October 27, 1998
    Publication date: November 6, 2003
    Inventors: THOMAS HAAF, EFIM ILYA GOLUB, GURUCHARAN REDDY, CHARLES MEYER RADDING
  • Publication number: 20030143533
    Abstract: In accordance with the objects outlined above, the present invention provides methods of diagnosing individuals at risk for a disease state which results in aberrant Rad51 loci. The methods comprise determining the distribution of Rad51 foci in a first tissue type of a first individual, and then comparing the distribution to the distribution of Rad51 foci from a second normal tissue type from the first individual or a second unaffected individual. A difference in the distributions indicates that the first individual is at risk for a disease state which results in aberrant Rad51 loci. Preferred disease states include cancer and disease states associated with apoptosis.
    Type: Application
    Filed: October 27, 1998
    Publication date: July 31, 2003
    Inventors: THOMAS HAAF, EFIM ILYA GOLUB, GURUCHARAN REDDY, CHARLES MEYER RADDING, DAVID C. WARD
  • Patent number: 6391564
    Abstract: Compositions and methods are provided for identifying and diagnosing individuals at risk for a disease state associated with aberrant Rad41 foci.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: May 21, 2002
    Assignee: Yale University
    Inventors: Thomas Haaf, Efim Ilya Golub, Gurucharan Reddy, Charles Meyer Radding, David C. Ward
  • Patent number: 6090539
    Abstract: Compositions and methods are provided for identifying agents which bind to or modulate Rad51.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: July 18, 2000
    Assignee: Yale University
    Inventors: Thomas Haaf, Efim Ilya Golub, Gurucharan Reddy, Charles Meyer Radding, David C. Ward
  • Patent number: 5989879
    Abstract: The invention relates to complexes of eukaryotic Rad52 protein and nucleic acids, and methods of using the complexes.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: November 23, 1999
    Assignee: Yale University
    Inventors: Gurucharan Reddy, Efim Ilya Golub, Charles Meyer Radding