Abstract: A method for fluorescent imaging of a subject, the method having the steps of: placing an illuminator in a surgical area of a subject, the illuminator having an emission band substantially similar to an fluorescence imaging agent; administering the fluorescence imaging agent to the subject; acquiring a plurality of images of the surgical area of the subject showing fluorescence intensity over a predetermined time period; and analyzing the plurality of images to determine changes in sensed fluorescence from the fluorescence imaging agent; wherein an exposure gain is applied to the images based on changes in detected intensity of the fluorescence from the illuminator.

Abstract: An endoscopic camera device having an optical assembly; a first image sensor in optical communication with the optical assembly, the first image sensor receiving a first exposure and transmitting a first low dynamic range image; a second image sensor in optical communication with the optical assembly, the second image sensor receiving a second exposure and transmitting a second low dynamic range image, the second exposure being higher than the first exposure; and a processor for receiving the first low dynamic range image and the second low dynamic range image; wherein the processor is configured to combine the first low dynamic range image and the second dynamic range image into a high dynamic range image using a luminosity value derived as a preselected percentage of a cumulative luminosity distribution of at least one of the first low dynamic range image and the second low dynamic range image.

Abstract: An endoscopic camera device having an optical assembly; a first image sensor in optical communication with the optical assembly, the first image sensor receiving a first exposure and transmitting a first low dynamic range image; a second image sensor in optical communication with the optical assembly, the second image sensor receiving a second exposure and transmitting a second low dynamic range image, the second exposure being higher than the first exposure; and a processor for receiving the first low dynamic range image and the second low dynamic range image; wherein the processor is configured to combine the first low dynamic range image and the second dynamic range image into a high dynamic range image using a luminosity value derived as a preselected percentage of a cumulative luminosity distribution of at least one of the first low dynamic range image and the second low dynamic range image.