Patents by Inventor Efrat Manoff

Efrat Manoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Letrozole purification process
    Patent number: 7465749
    Abstract: Provided is a process for purifying a letrozole product that contains an isoletrozole impurity, which process preferably includes converting at least a portion of the isoletrozole impurity into 4,4?-dicyanobenzophenone and removing 4,4?-dicyanobenzophenone, to produce a purified letrozole product.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: December 16, 2008
    Assignee: Chemagis, Ltd.
    Inventors: Michal Hasson, Hila Isenberg, Efrat Manoff, Moshe Bentolila, Oded Friedman, Lior Zelikovitch
  • PROCESS FOR PREPARING MONTELUKAST SODIUM CONTAINING CONTROLLED LEVELS OF IMPURITIES
    Publication number: 20080188664
    Abstract: The present invention is directed to a process of preparing montelukast or a salt thereof with minimal amounts of impurities, such as a dehydration impurity (compound (VI)) or a cyclic ether impurity (compound (VIII)).
    Type: Application
    Filed: January 10, 2008
    Publication date: August 7, 2008
    Applicant: CHEMAGIS LTD.
    Inventors: Michael Brand, Alex Weisman, Yael Gafni, Lior Zelikovitch, Guy Davidi, Efrat Manoff
  • Letrozole purification process
    Publication number: 20070112203
    Abstract: Provided is a process for purifying a letrozole product that contains an isoletrozole impurity, which process preferably includes converting at least a portion of the isoletrozole impurity into 4,4?-dicyanobenzophenone and removing 4,4?-dicyanobenzophenone, to produce a purified letrozole product.
    Type: Application
    Filed: August 3, 2006
    Publication date: May 17, 2007
    Applicant: CHEMAGIS LTD.
    Inventors: Michal Hasson, Hila Isenberg, Efrat Manoff, Moshe Bentolila, Oded Friedman, Lior Zelikovitch