Patents by Inventor Efren Guillermo Delos Santos

Efren Guillermo Delos Santos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and TACE inhibitors
    Patent number: 7282496
    Abstract: Compounds of the formula are useful in treating disease conditions mediated by TNF-?, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease, degenerative cartilage loss, graft rejection, cachexia, inflammation, fever, insulin resistance, septic shock, congestive heart failure, inflammatory disease of the central nervous system, inflammatory bowel disease and HIV.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: October 16, 2007
    Assignee: Wyeth Holdings Corporation
    Inventors: Vincent Premaratna Sandanayaka, Efren Guillermo Delos Santos
  • Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and tace inhibitors
    Publication number: 20030130238
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 10, 2003
    Applicant: American Cyanamid Company
    Inventors: Vincent Premaratna Sandanayaka, Efren Guillermo Delos Santos
  • 2,3,4,5-tetrahydro-1H-(1,4)benzodiazepine-3-hydroxamic acids
    Patent number: 6544984
    Abstract: Compounds having the following formula:   are useful in treating disease conditions mediated by matrix metalloproteinases and TACE, such as tumor growth, osteoarthritis, rheumatoid arthritis and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: April 8, 2003
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Efren Guillermo Delos Santos, Jeremy Ian Levin, James Ming Chen
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5968930
    Abstract: Tricyclic diazepines of the formula: wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: October 19, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5968937
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: October 19, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5889001
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: March 30, 1999
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5854237
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: December 29, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5843944
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: December 1, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5736540
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: April 7, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos
  • Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
    Patent number: 5733905
    Abstract: Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: March 31, 1998
    Assignee: American Cyanamid Company
    Inventors: Jay Donald Albright, Marvin Fred Reich, Fuk-Wah Sum, Efren Guillermo Delos Santos