Patents by Inventor Efrosini Kokkoli

Efrosini Kokkoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORGANO-PHOSPHATE MODIFIED METAL ORGANIC FRAMEWORKS AND APPLICATIONS
    Publication number: 20240139722
    Abstract: Disclosed is a method to modify metal-organic frameworks (MOFs) by irreversible adsorption of nucleotides including, but not limited to, adenosine triphosphate (ATP), guanosine triphosphate (GTP), deoxyadenosine triphosphate (dATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP), the modified MOFs, and the use of the modified MOFs as adsorbents and catalysts.
    Type: Application
    Filed: October 27, 2023
    Publication date: May 2, 2024
    Inventors: Michael TSAPATSIS, Efrosini KOKKOLI, Danyu WANG
  • Nucleic acid amphiphiles and nanostructures
    Patent number: 10415040
    Abstract: Provided herein are nucleic acid amphiphiles and nanostructures such as nanotubes twisted nanotapes and helical nanotapes that comprise the amphiphiles as well as methods to deliver therapeutic agents with the nanostructures.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: September 17, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Efrosini Kokkoli, Timothy R. Pearce, Huihui Kuang
  • NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES
    Publication number: 20170218367
    Abstract: Provided herein are nucleic acid amphiphiles and nanostructures such as nanotubes twisted nanotapes and helical nanotapes that comprise the amphiphiles as well as methods to deliver therapeutic agents with the nanostructures.
    Type: Application
    Filed: June 22, 2015
    Publication date: August 3, 2017
    Inventors: Efrosini Kokkoli, Timothy R. Pearce, Huihui Kuang
  • Fractalkine binding polynucleotides and methods of use
    Patent number: 8883989
    Abstract: Provided herein are polynucleotides that bind to fractalkine. In one embodiment, a polynucleotide includes the polynucleotide sequence SEQ ID NO:1 or a sequence having at least 80% identity to SEQ ID NO:1. Also provided herein are structures that include such a polynucleotide present on its surface, including 2-dimentional and 3-dimentional structures. Also provided are compositions that include such a polynucleotide, and methods for using the polynucleotides.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: November 11, 2014
    Assignee: Regents of The University of Minnesota
    Inventors: Efrosini Kokkoli, Brett M. Waybrant, Srinand Sreevatsan, Ping Wang
  • FRACTALKINE BINDING POLYNUCLEOTIDES AND METHODS OF USE
    Publication number: 20130123347
    Abstract: Provided herein are polynucleotides that bind to fractalkine. In one embodiment, a polynucleotide includes the polynucleotide sequence SEQ ID NO:1 or a sequence having at least 80% identity to SEQ ID NO:1. Also provided herein are structures that include such a polynucleotide present on its surface, including 2-dimentional and 3-dimentional structures. Also provided are compositions that include such a polynucleotide, and methods for using the polynucleotides.
    Type: Application
    Filed: October 18, 2012
    Publication date: May 16, 2013
    Inventors: EFROSINI KOKKOLI, Brett M. Waybrant, Srinand Sreevatsan, Ping Wang
  • Compounds that bind ??integrin and methods of use
    Patent number: 8343539
    Abstract: The present invention provides biologically active compounds that bind an ?5?1 integrin. Also included in the present invention are methods for using such biologically active compounds.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: January 1, 2013
    Assignee: Regents of the University of Minnesota
    Inventors: Efrosini Kokkoli, Anastasia Mardilovich, Ashish Garg
  • COMPOUNDS THAT BIND ALPHA5BETA1 INTEGRIN AND METHODS OF USE
    Publication number: 20090280165
    Abstract: The present invention provides biologically active compounds that bind an ?s?i integrin. Also included in the present invention are methods for using such biologically active compounds.
    Type: Application
    Filed: July 13, 2007
    Publication date: November 12, 2009
    Applicant: Regents of the University of Minnesota
    Inventors: Efrosini Kokkoli, Anastasia Mardilovich, Ashish Garg