Patents by Inventor Egbert Bakker

Egbert Bakker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic test kit for determining a predisposition for breast and ovarian cancer, materials and methods for such determination
    Patent number: 7507800
    Abstract: The present invention relates generally to the field of human genetics, and more specifically to the detection of a specific type of germline mutations in the BRCA1 gene, which will predispose to breast and ovarian cancer. In addition, the invention relates to the molecular genetic mechanism that may have mediated the genesis of these mutations, in particular the role of Alu repetitive DNA elements present in the intronic regions of BRCA1. The invention further relates to somatic mutations of this type in the BRCA1 gene in human breast and ovarian cancer, and their use in the diagnosis and prognosis of human breast and ovarian cancer. The invention more particularly relates to the screening of this type of BRCA1 mutations in human genomic DNA, which are useful for the diagnosis of inherited predisposition to breast and ovarian cancer.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: March 24, 2009
    Assignee: Rijksuniversiteit te Leiden
    Inventors: Garrit-Jan Boudewijn van Ommen, Anne Petrij-Bos, Egbert Bakker, Peter Devilee
  • Diagnostic test kit for determining a predisposition for breast and ovarian cancer, materials and methods for such determination
    Publication number: 20050019782
    Abstract: The present invention relates generally to the field of human genetics, and more specifically to the detection of a specific type of germline mutations in the BRCA1 gene, which will predispose to breast and ovarian cancer. In addition, the invention relates to the molecular genetic mechanism that may have mediated the genesis of these mutations, in particular the role of Alu repetitive DNA elements present in the intronic regions of BRCA1. The invention further relates to somatic mutations of this type in the BRCA1 gene in human breast and ovarian cancer, and their use in the diagnosis and prognosis of human breast and ovarian cancer. The invention more particularly relates to the screening of this type of BRCA1 mutations in human genomic DNA, which are useful for the diagnosis of inherited predisposition to breast and ovarian cancer.
    Type: Application
    Filed: September 3, 2003
    Publication date: January 27, 2005
    Inventors: Garrit-Jan van Ommen, Anne Petrij-Bos, Egbert Bakker, Peter Devilee
  • Diagnostic test kit for determining a predisposition for breast and ovarian cancer, materials and methods for such determination
    Patent number: 6733966
    Abstract: The present invention relates generally to the field of human genetics, and more specifically to the detection of a specific type of germline mutations in the BRCA1 gene, which will predispose to breast and ovarian cancer. In addition, the invention relates to the molecular genetic mechanism that may have mediated the genesis of these mutations, in particular the role of Alu repetitive DNA elements present in the intronic regions of BRCA1. The invention further relates to somatic mutations of this type in the BRCA1 gene in human breast and ovarian cancer, and their use in the diagnosis and prognosis of human breast and ovarian cancer. The invention more particularly relates to the screening of this type of BRCA1 mutations in human genomic DNA, which are useful for the diagnosis of inherited predisposition to breast and ovarian cancer.
    Type: Grant
    Filed: April 24, 2000
    Date of Patent: May 11, 2004
    Assignee: Rijksuniversiteit Te Leiden
    Inventors: Garrit-Jan Boudewijn van Ommen, Anne Petrij-Bos, Egbert Bakker, Peter Devilee