Patents by Inventor Egisto Boschetti
Egisto Boschetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10265271Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.Type: GrantFiled: May 16, 2008Date of Patent: April 23, 2019Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti
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Patent number: 9803184Abstract: The invention relates to a method for immobilizing nucleic ligands including at least one reactive amine function, by grafting on an activated solid substrate, including a step of coupling said nucleic acids on said activated solid substrate having a pH of less than 6.Type: GrantFiled: December 30, 2011Date of Patent: October 31, 2017Assignee: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIESInventors: Egisto Boschetti, Gérald Perret
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Patent number: 9308169Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.Type: GrantFiled: May 2, 2012Date of Patent: April 12, 2016Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti
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Patent number: 9295648Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: GrantFiled: November 8, 2013Date of Patent: March 29, 2016Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Patent number: 9205053Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: GrantFiled: July 31, 2009Date of Patent: December 8, 2015Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Patent number: 9017710Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.Type: GrantFiled: August 22, 2008Date of Patent: April 28, 2015Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti, Richard Thomas
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Patent number: 8932637Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.Type: GrantFiled: August 8, 2013Date of Patent: January 13, 2015Assignee: Biosphere Medical. Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Patent number: 8906608Abstract: The present invention relates to the fields of molecular biology, combinatorial chemistry and biochemistry. Particularly, the present invention describes methods and kits for dynamically reducing the variance between analyte taken from complex mixtures.Type: GrantFiled: July 28, 2006Date of Patent: December 9, 2014Assignees: Bio-Rad Laboratories, Inc., American National Red CrossInventors: Egisto Boschetti, David Hammond
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Patent number: 8778333Abstract: The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.Type: GrantFiled: January 16, 2008Date of Patent: July 15, 2014Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti
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Patent number: 8741351Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.Type: GrantFiled: February 13, 2012Date of Patent: June 3, 2014Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti
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Patent number: 8697137Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.Type: GrantFiled: March 23, 2001Date of Patent: April 15, 2014Assignee: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Egisto Boschetti
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Patent number: 8673266Abstract: The present invention relates to microspheres useful for embolization which comprises polyvinylalcohol. The present invention also relates to an injectable suspension suitable for embolization which comprises the polyvinylalcohol microspheres and a suitable liquid carrier. The present invention further relates to a method for prophylactic or therapeutic embolization which comprises administering to a mammal an injectable suspension containing the polyvinylalcohol microspheres and a suitable liquid carrier. Finally, the present invention relates to a process for producing the polyvinylalcohol microspheres.Type: GrantFiled: January 12, 2010Date of Patent: March 18, 2014Assignee: Biosphere Medical, S.A.Inventor: Egisto Boschetti
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Publication number: 20140065233Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: November 8, 2013Publication date: March 6, 2014Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Patent number: 8658215Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: GrantFiled: August 7, 2013Date of Patent: February 25, 2014Assignee: Biospehere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Publication number: 20130344567Abstract: The invention relates to a method for immobilizing nucleic ligands including at least one reactive amine function, by grafting on an activated solid substrate, including a step of coupling said nucleic acids on said activated solid substrate having a pH of less than 6.Type: ApplicationFiled: December 30, 2011Publication date: December 26, 2013Applicant: LFB BiotechnologiesInventors: Egisto Boschetti, Gérald Perret
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Publication number: 20130323316Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: August 7, 2013Publication date: December 5, 2013Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Publication number: 20130323317Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: August 8, 2013Publication date: December 5, 2013Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
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Patent number: 8491791Abstract: The present invention contemplates various devices that are configured to separate a sample, which contains more than one unique species, into any desired number of sub-samples by passing the sample across a like number of separation media configured for a first separation protocol. Each of the sub-samples may be further separated by an additional separation protocol, thereby creating a plurality of mini-samples, each of which may be further separated and/or analyzed. The invention also contemplates using a simple method of using conduits to form a fluid path that passes through a plurality of separation media, each of which media is configured to isolate a particular sub-sample. After various sub-samples of the sample are isolated by the various separation media, the conduits may be removed, thereby enabling each of the isolated sub-samples to be further separated and/or analyzed independent of any other sub-sample.Type: GrantFiled: July 18, 2012Date of Patent: July 23, 2013Assignee: Bio-Rad Laboratories, Inc.Inventors: Lee O. Lomas, Jian Ding, Egisto Boschetti
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Publication number: 20120309644Abstract: The present invention contemplates various devices that are configured to separate a sample, which contains more than one unique species, into any desired number of sub-samples by passing the sample across a like number of separation media configured for a first separation protocol. Each of the sub-samples may be further separated by an additional separation protocol, thereby creating a plurality of mini-samples, each of which may be further separated and/or analyzed. The invention also contemplates using a simple method of using conduits to form a fluid path that passes through a plurality of separation media, each of which media is configured to isolate a particular sub-sample. After various sub-samples of the sample are isolated by the various separation media, the conduits may be removed, thereby enabling each of the isolated sub-samples to be further separated and/or analyzed independent of any other sub-sample.Type: ApplicationFiled: July 18, 2012Publication date: December 6, 2012Applicant: Bio-Rad Laboratories, Inc.Inventors: Lee O. Lomas, Jian Ding, Egisto Boschetti
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Publication number: 20120213831Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.Type: ApplicationFiled: May 2, 2012Publication date: August 23, 2012Applicant: BIOSPHERE MEDICAL, INC.Inventors: Jean-Marie Vogel, Egisto Boschetti