Patents by Inventor Egisto Boschetti

Egisto Boschetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10265271
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: April 23, 2019
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti
  • Patent number: 9803184
    Abstract: The invention relates to a method for immobilizing nucleic ligands including at least one reactive amine function, by grafting on an activated solid substrate, including a step of coupling said nucleic acids on said activated solid substrate having a pH of less than 6.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: October 31, 2017
    Assignee: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
    Inventors: Egisto Boschetti, Gérald Perret
  • Patent number: 9308169
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: April 12, 2016
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti
  • Patent number: 9295648
    Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: March 29, 2016
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Patent number: 9205053
    Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: December 8, 2015
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Patent number: 9017710
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: April 28, 2015
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti, Richard Thomas
  • Patent number: 8932637
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: January 13, 2015
    Assignee: Biosphere Medical. Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Patent number: 8906608
    Abstract: The present invention relates to the fields of molecular biology, combinatorial chemistry and biochemistry. Particularly, the present invention describes methods and kits for dynamically reducing the variance between analyte taken from complex mixtures.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: December 9, 2014
    Assignees: Bio-Rad Laboratories, Inc., American National Red Cross
    Inventors: Egisto Boschetti, David Hammond
  • Patent number: 8778333
    Abstract: The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: July 15, 2014
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti
  • Patent number: 8741351
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: June 3, 2014
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti
  • Patent number: 8697137
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: April 15, 2014
    Assignee: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Egisto Boschetti
  • Patent number: 8673266
    Abstract: The present invention relates to microspheres useful for embolization which comprises polyvinylalcohol. The present invention also relates to an injectable suspension suitable for embolization which comprises the polyvinylalcohol microspheres and a suitable liquid carrier. The present invention further relates to a method for prophylactic or therapeutic embolization which comprises administering to a mammal an injectable suspension containing the polyvinylalcohol microspheres and a suitable liquid carrier. Finally, the present invention relates to a process for producing the polyvinylalcohol microspheres.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: March 18, 2014
    Assignee: Biosphere Medical, S.A.
    Inventor: Egisto Boschetti
  • Publication number: 20140065233
    Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Patent number: 8658215
    Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: February 25, 2014
    Assignee: Biospehere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Publication number: 20130344567
    Abstract: The invention relates to a method for immobilizing nucleic ligands including at least one reactive amine function, by grafting on an activated solid substrate, including a step of coupling said nucleic acids on said activated solid substrate having a pH of less than 6.
    Type: Application
    Filed: December 30, 2011
    Publication date: December 26, 2013
    Applicant: LFB Biotechnologies
    Inventors: Egisto Boschetti, Gérald Perret
  • Publication number: 20130323317
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Applicant: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Publication number: 20130323316
    Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
    Type: Application
    Filed: August 7, 2013
    Publication date: December 5, 2013
    Applicant: Biosphere Medical, Inc.
    Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
  • Patent number: 8491791
    Abstract: The present invention contemplates various devices that are configured to separate a sample, which contains more than one unique species, into any desired number of sub-samples by passing the sample across a like number of separation media configured for a first separation protocol. Each of the sub-samples may be further separated by an additional separation protocol, thereby creating a plurality of mini-samples, each of which may be further separated and/or analyzed. The invention also contemplates using a simple method of using conduits to form a fluid path that passes through a plurality of separation media, each of which media is configured to isolate a particular sub-sample. After various sub-samples of the sample are isolated by the various separation media, the conduits may be removed, thereby enabling each of the isolated sub-samples to be further separated and/or analyzed independent of any other sub-sample.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: July 23, 2013
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Lee O. Lomas, Jian Ding, Egisto Boschetti
  • Publication number: 20120309644
    Abstract: The present invention contemplates various devices that are configured to separate a sample, which contains more than one unique species, into any desired number of sub-samples by passing the sample across a like number of separation media configured for a first separation protocol. Each of the sub-samples may be further separated by an additional separation protocol, thereby creating a plurality of mini-samples, each of which may be further separated and/or analyzed. The invention also contemplates using a simple method of using conduits to form a fluid path that passes through a plurality of separation media, each of which media is configured to isolate a particular sub-sample. After various sub-samples of the sample are isolated by the various separation media, the conduits may be removed, thereby enabling each of the isolated sub-samples to be further separated and/or analyzed independent of any other sub-sample.
    Type: Application
    Filed: July 18, 2012
    Publication date: December 6, 2012
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Lee O. Lomas, Jian Ding, Egisto Boschetti
  • Publication number: 20120213831
    Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
    Type: Application
    Filed: May 2, 2012
    Publication date: August 23, 2012
    Applicant: BIOSPHERE MEDICAL, INC.
    Inventors: Jean-Marie Vogel, Egisto Boschetti