Patents by Inventor Egvenia Alpert

Egvenia Alpert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of ear disorders
    Patent number: 8431692
    Abstract: The present invention relates to pharmaceutical compositions useful for topical, non-invasive delivery of an oligonucleotide to the ear and to methods for the treatment of an ear disorder, including hearing loss arising from chemical-induced ototoxicity, acoustic trauma and presbycusis; and microbial infections. The method comprises topically administering to the ear of a subject in need thereof a pharmaceutical composition comprising an inhibitory oligonucleotide, a permeability enhancer and a pharmaceutically acceptable carrier, wherein the oligonucleotide reduces or inhibits expression of a gene associated with the ear disorder in the subject.
    Type: Grant
    Filed: June 7, 2009
    Date of Patent: April 30, 2013
    Assignee: Quark Pharmaceuticals, Inc.
    Inventors: Egvenia Alpert, Igor Spivak, Amir Bar-Ilan
  • COMPOSITIONS AND METHODS FOR TREATMENT OF EAR DISORDERS
    Publication number: 20110142917
    Abstract: The present invention relates to pharmaceutical compositions useful for topical, non-invasive delivery of an oligonucleotide to the ear and to methods for the treatment of an ear disorder, including hearing loss arising from chemical-induced ototoxicity, acoustic trauma and presbycusis; and microbial infections. The method comprises topically administering to the ear of a subject in need thereof a pharmaceutical composition comprising an inhibitory oligonucleotide, a permeability enhancer and a pharmaceutically acceptable carrier, wherein the oligonucleotide reduces or inhibits expression of a gene associated with the ear disorder in the subject.
    Type: Application
    Filed: June 7, 2009
    Publication date: June 16, 2011
    Inventors: Egvenia Alpert, Igor Spivak, Amir Bar-Ilan