Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.

Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.

Abstract: The present invention is related to compounds having general formula Z-OC (CRn1Rn2)—CO-Z wherein Z=OH or NH2 and n1=n2=1 to 8, useful for modulation of immune response by inducing differentiation of dendritic cells consisting novel class of amino acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids, and their amides) of the general formula ZOC—CR3R4—CR2(NHR1)—COOH, ZOC—CR5R6—CR3R4—CR1(NHR2)—COOH, ZOC—CR7R8—CR5R6—CR3R4—CR1N2)—COOH wherein Z=OH or NH2; R1 to R8 denotes H, SO3H, or OSO3H. In addition, the dicarboxylic acids and their amides ZOC—(CH2)n—CR1R2—COOH, where Z=OH or NH2; and n=1, 2, 3. The groups R1/R2=H/SO3H or OSO3H or CH2—SO3H or CH2—OSO3H and vice versa. The factors also contain different divalent metal cations such as Mg, Ca and Zn.

Abstract: The present invention is related to compounds having general formula Z-OC(CRn1Rn2)—CO-Z wherein Z=OH or NH2 and n1=n2=1 to 8, for modulation of immune response by differentiation dendritic cells consisting novel class of amino acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids, and their amides) of the general formula ZOC—CR3R4—CR2(NHR1)—COOH, ZOC—CR5R6—CR3R4—C(NHR2)—COOH, ZOC—CR7R8—CR5R6—CR3R4—CR1(NHR2)—COOH wherein Z=OH or NH2; R1 to R8 denotes H, SO3H, or OSO3H. In addition, the dicarboxylic acids and their amides ZOC—(CH2)n—CR1R2—COOH, where Z=OH or NH2; and n=1, 2, 3. The groups R1/R2=H/SO3H or OSO3H or CH2—SO3H or CH2—OSO3H and vice versa. The factors also contain different divalent metal cations such as Mg, Ca and Zn.

Abstract: A method of determining the Volume Scattering Function of Ocean Waters in the backward direction using a Satellite Ocean Color Sensor the said method made to exploit the geometry of the sun-ocean-satellite detector to function as a backscatter system comprising of the sun [1] as a source of radiation, the ocean as the sampling volume [2], and the satellite ocean color sensor [3] as the detector of the backscattered flux from the ocean emanating from separate ocean pixels arranged on a scan line across the track of the satellite payload and arriving at corresponding pixels on the CCD array detector of the satellite sensor [3]; the output signals from each electronic pixel of the detector is shown to be related to the Volume Scattering Function at a fixed scattering angles (?) which bears a direct relation to the cosines of the solar incident angle (?s) and the angle (?p) of the upwelled flux at the ocean surface, the Remotely Sensed Reflectance (Rrs), and the diffuse attenuation coefficient (Kd) thereby result

Abstract: A method of determining the Volume Scattering Function of Ocean Waters in the backward direction using a Satellite Ocean Color Sensor the said method made to exploit the geometry of the sun-ocean-satellite detector to function as a backscatter system comprising of the sun [1] as a source of radiation, the ocean as the sampling volume [2], and the satellite ocean color sensor [3] as the detector of the backscattered flux from the ocean emanating from separate ocean pixels arranged on a scan line across the track of the satellite payload and arriving at corresponding pixels on the CCD array detector of the satellite sensor [3]; the output signals from each electronic pixel of the detector is shown to be related to the Volume Scattering Function at a fixed scattering angles (?) which bears a direct relation to the cosines of the solar incident angle (?s) and the angle (?p) of the upwelled flux at the ocean surface, the Remotely Sensed Reflectance (Rrs), and the diffuse attenuation coefficient (Kd) thereby result

Abstract: The present invention relates to system for calibrating plurality of pressure transducers, said system comprising plurality of pressure transducers (13.1 to 13.n) mounted on a mounting means (12) which receives pressure input from a pressure source (11) via a hollow pipe (14) and distributes the pressure evenly to all the pressure transducers, said plurality of pressure transducers are mounted on the mounting means and placed inside a vessel (15) as to vary the temperature of the pressure transducers, said pressure source is also connected to a standard pressure transducer (17) whose temperature is maintained at the same level as that of pressure transducers (13.1 to 13.n).

Abstract: The present invention relates to a segmented cylindrical tide staff system [11] for erection at remote areas for dynamic calibration of electronic tide meters and computer models of tides, said tide staff system consisting of plurality of cylindrical tubes [12], said cylindrical tube being coupled to a flange [13] at its end through a circular orthogonal hole [20] drilled on a flat surface of the flange, said flange being provided with plurality of equally spaced slots [15] drilled on the flat surface of the flange, an outwardly protruding tide indicating arm [14] being mounted on the flange wherein said tide indicating arm consists of two mutually orthogonal planes [22] and [23], wherein plane [22] is perpendicular to the axis of the tide staff and plane [23] is parallel to the axis of the tide staff, said perpendicular plane [22] being provided with a mounting terminal [21] and a circular

Abstract: The present invention relates to a device useful as a controllable variable speed thruster-driven oceanographic profiler for coastal waters for measuring the vertical structure of chosen properties of the oceanic water column.

Abstract: The present invention relates to a segmented cylindrical tide staff system [11] for erection at remote areas for dynamic calibration of electronic tide meters and computer models of tides, said tide staff system consisting of plurality of cylindrical tubes [12], said cylindrical tube being coupled to a flange [13] at its end through a circular orthogonal hole [20] drilled on a flat surface of the flange, said flange being provided with plurality of equally spaced slots [15] drilled on the flat surface of the flange, an outwardly protruding tide indicating arm [14] being mounted on the flange wherein said tide indicating arm consists of two mutually orthogonal planes [22] and [23], wherein plane [22] is perpendicular to the axis of the tide staff and plane [23] is parallel to the axis of the tide staff, said perpendicular plane [22] being provided with a mounting terminal [21] and a circular

Abstract: The present invention relates to a system for calibrating plurality of pressure transducers, said system comprising plurality of pressure transducers (13.1 to 13.n) mounted on a mounting means (12) which receives pressure input from a pressure source (11) via a hollow cylinder (14) and distributes the pressure evenly to all the pressure transducers, said plurality of pressure transducers are mounted on the mounting means and placed inside a vessel (15) so as to vary the temperature of the pressure transducers, said pressure source is also connected to a standard pressure transducer (17) whose temperature is maintained at the same level as that of pressure transducers(13.1 to 13.n).

Abstract: The present invention relates to a device useful as a controllable variable speed thruster-driven oceanographic profiler for coastal waters for measuring the vertical structure of chosen properties of the oceanic water column.

Abstract: The present invention relates to a pressure housing for in-water pressure based systems and to a method for improving the life of the transducers and electronics of underwater systems by maintaining a humidity-free and clean environment around them by avoiding the entry of humidity, dust, or any suspended particles in the air during occasional data offloading and battery replacement in a humid and dust-laden field station; improving the ease of closing and opening of the pressure housing by the use of a novel arrangement thereby avoiding the use of conventionally employed cumbersome protruding and corrosion-prone locking devices such as screws, bolts, or clamps; and implementing reliable transmission of water pressure to the pressure port of the transducer, simultaneously minimizing the errors arising from dynamic pressure effects, preventing its chemical corrosion from saline water, and arresting bio-fouling in the vicinity of the pressure inlet.

Abstract: The invention relates to a method for enhancing levels of polyunsaturated fatty acid levels in thraustochytrid fungi, using media supplemented with polyvinyl pyrrolidone (PVP) to increase viscosity and which comprises: (a) providing a thraustochytrid fungus strain NIO-TH 21, corresponding to the species Ulkenia radiata Gaertner, being the culture with Accession No. AB22115 of the National Institute of Bioscience and Human-Technology, Japan; (b) inoculating the above said strain in a culture medium; (c) growing the culture for 2 days at a temperature ranging from 25 to 30° C.; (d) obtaining the cultures for use as innoculum using the above said medium to inoculate a medium with different concentrations of polyvinyl pyrrolidone (PVP); (e) growing the culture separately for 2 to 5 days at a temperature ranging from 25 to 30° C.; and (f) harvesting the cells from the above culture by centrifugation and extracting the enhanced amounts of docosahexaenoic acid (DHA) and eicosapentaenoic acids (EPA).