Patents by Inventor Ehud Klein

Ehud Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for diagnosis of schizophrenia
    Patent number: 8420308
    Abstract: The present invention provides methods and kits for the diagnosis of schizophrenia, which employ mitochondrial complex I as a peripheral biological marker for schizophrenia. In an embodiment of the invention, the present invention provides a method for diagnosing schizophrenia in a subject by determining the level of m-RNA or protein mitochondrial complex I subunits and its activity by determining the cellular basal respiration through complex I enzyme.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: April 16, 2013
    Assignee: Technion R&D Foundation Ltd.
    Inventors: Dorit Ben-Shachar, Ehud Klein
  • METHODS AND KITS FOR DIAGNOSIS OF SCHIZOPHRENIA
    Publication number: 20090162854
    Abstract: The present invention provides methods and kits for the diagnosis of schizophrenia, which employ mitochondrial complex I as a peripheral biological marker for schizophrenia. In an embodiment of the invention, the present invention provides a method for diagnosing schizophrenia in a subject by determining the level of m-RNA or protein mitochondrial complex I subunits and its activity by determining the cellular basal respiration through complex I enzyme.
    Type: Application
    Filed: October 27, 2008
    Publication date: June 25, 2009
    Inventors: Dorit Ben-Shachar, Ehud Klein
  • Methods and kits for diagnosis of schizophrenia
    Patent number: 7442496
    Abstract: The present invention provides methods and kits for the diagnosis of schizophrenia, which employ mitochondrial complex I as a peripheral biological marker for schizophrenia. In one embodiment, the present invention provides a method for diagnosing schizophrenia in a subject by determining the level of activity of a mitochondrial complex I enzyme in a sample obtained from the subject, and comparing the level of activity in the sample with a normative value of mitochondrial complex I enzyme activity, wherein an altered level of activity of mitochondrial complex I enzyme in the sample compared with the normative value is indicative of the subject having schizophrenia.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: October 28, 2008
    Assignee: Technion R&D Foundation Ltd. Business Development & Financial Control Dept.
    Inventors: Dorit Ben-Shachar, Ehud Klein