Patents by Inventor Ehud QIMRON

Ehud QIMRON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210290704
    Abstract: The invention related to a kit or a system comprising two elements or components. The first component (i) is a selective component comprising a nucleic acid sequence comprising at least one proto-spacer. The second component (ii) comprises at least one sensitizing component comprising at least one cas gene and at least one CRISPR array. It should be noted that at least one spacer of the CRISPR targets a proto-spacer comprised within a pathogenic gene of a bacterium so as to specifically inactivate said pathogenic gene in said bacterium and wherein at least one spacer of said CRISPR targets a proto-spacer comprised within said selective component of (i) so as to specifically inactivate said selective component. The invention further provides method using the components or kits of the invention for interference with a horizontal transfer of a pathogenic gene between bacteria and for preventing a pathologic condition in a mammalian subject caused by a bacterial infection.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 23, 2021
    Applicant: TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP
    Inventors: Ehud QIMRON, Ido YOSEF, Miriam MANOR
  • Patent number: 11060114
    Abstract: Provided is a kit or a system including two elements or components. The first component (i) is a selective component including a nucleic acid sequence and at least one proto-spacer. The second component (ii) includes at least one sensitizing component including at least one cas gene and at least one CRISPR array. At least one spacer of the CRISPR targets a proto-spacer included within a pathogenic gene of a bacterium so as to specifically inactivate said pathogenic gene in said bacterium and wherein at least one spacer of said CRISPR targets a proto-spacer included within said selective component of (i) so as to specifically inactivate said selective component. Further provided is a method using the components or kits of the invention for interference with a horizontal transfer of a pathogenic gene between bacteria and for preventing a pathologic condition in a mammalian subject caused by a bacterial infection.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: July 13, 2021
    Assignee: TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP
    Inventors: Ehud Qimron, Ido Yosef, Miriam Manor
  • Publication number: 20200329685
    Abstract: The present invention provides systems and non-invasive methods for gender selection of eukaryotic organisms More specifically, the invention applies the CRISPR-Cas system as well as any derivatives and fusion proteins thereof for creation of transgenic eukaryotic organisms and for selecting the desired gender of the resulting progeny.
    Type: Application
    Filed: January 3, 2019
    Publication date: October 22, 2020
    Inventors: Ehud QIMRON, Ido YOSEF, Mordechay GERLIC
  • Publication number: 20190321422
    Abstract: Provided is a platform for of the preparation of improved nucleic acid delivery vehicles, specifically, vehicles having an extended host recognition ability. Further provided are improved vehicles, compositions and uses thereof.
    Type: Application
    Filed: June 29, 2017
    Publication date: October 24, 2019
    Applicant: Technology Innovation Momentum Fund (Israel) Limited Partnership
    Inventors: Ehud QIMRON, Ido YOSEF, Moran GOREN
  • Publication number: 20170260546
    Abstract: Provided is a kit or a system including two elements or components. The first component (i) is a selective component including a nucleic acid sequence and at least one proto-spacer. The second component (ii) includes at least one sensitizing component including at least one cas gene and at least one CRISPR array. At least one spacer of the CRISPR targets a proto-spacer included within a pathogenic gene of a bacterium so as to specifically inactivate said pathogenic gene in said bacterium and wherein at least one spacer of said CRISPR targets a proto-spacer included within said selective component of (i) so as to specifically inactivate said selective component. Further provided is a method using the components or kits of the invention for interference with a horizontal transfer of a pathogenic gene between bacteria and for preventing a pathologic condition in a mammalian subject caused by a bacterial infection.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Applicant: TECHNOLOGY INNOVATION MOMENTUM FUND (ISREAL) LIMITED PARTNERSHIP
    Inventors: Ehud QIMRON, Ido YOSEF, Miriam MANOR
  • Patent number: 8865158
    Abstract: A genetically modified bacteriophage is disclosed which comprises: (i) an exogenous polynucleotide which encodes an agent which reduces the toxicity of a bacterium; and (ii) an exogenous polynucleotide which encodes a selectable marker. Uses thereof and kits comprising same are also disclosed.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: October 21, 2014
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud Qimron, Rotem Edgar, Nir Friedman
  • Publication number: 20130315869
    Abstract: A genetically modified bacteriophage is disclosed which comprises: (i) an exogenous polynucleotide which encodes an agent which reduces the toxicity of a bacterium; and (ii) an exogenous polynucleotide which encodes a selectable marker. Uses thereof and kits comprising same are also disclosed.
    Type: Application
    Filed: May 22, 2012
    Publication date: November 28, 2013
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud QIMRON, Rotem Edgar, Nir Friedman