Abstract: The receptor of parasporin-1 has been found to be beclin-1. Based on the finding, the present invention provides a method of determining the sensitivity of a cell to parasporin-1, comprising measuring the expression level of beclin-1 polypeptide on the cell membrane or in a membrane fraction of a cell; an inhibitor of the cytotoxicity of parasporin-1, containing beclin-1 polypeptide etc.; a method of screening for a substance capable of inhibiting the cytotoxicity of parasporin-1, comprising evaluating the degree of binding of parasporin-1 to beclin-1 polypeptide in the presence of a test substance; a cell death inducer containing an antibody that specifically recognizes beclin-1 polypeptide; a method of screening for a substance capable of inducing cell death, comprising evaluating the binding of a test substance to beclin-1 polypeptide, and the like.

Abstract: A novel Bacillus thuringiensis strain deposited at the International Depository Authority of Health Canada in Winnipeg under accession number IDAC010201-5, its crystal gene having the sequence SEQ ID NO: 1 and crystal protein encoded by same having the sequence SEQ ID NO: 2 and uses thereof. More specifically, the present invention is concerned with a novel Bacillus thuringiensis, novel cry31 protoxin and toxin, nucleotide sequences encoding same and anti-cancer therapeutic applications for the toxin.

Abstract: A novel Bacillus thuringiensis strain deposited at the International Depository Authority of Health Canada in Winnipeg under accession number IDAC010201-5, its crystal gene having the sequence SEQ ID NO: 1 and crystal protein encoded by same having the sequence SEQ ID NO: 2 and uses thereof. More specifically, the present invention is concerned with a novel Bacillus thuringiensis, novel cry31 protoxin and toxin, nucleotide sequences encoding same and anti-cancer therapeutic applications for the toxin.

Abstract: The present invention provides a protein consisting of the amino acid sequence represented by SEQ ID NO: 2, as well as proteins comprising an amino acid sequence wherein one or more amino acids are deleted, substituted, added or inserted in the amino acid sequence represented by SEQ ID NO: 2, whose activated form has a cell-recognizing activity and/or a cytopathic activity. The present invention also provides a nucleic acid molecule consisting of the nucletide sequence represented by SEQ ID NO: 1, as well as nucleic acid molecules which hybridize under stringent conditions to a nucleic acid molecule having a nucleotide sequence complementary to the nucleotide sequence represented by SEQ ID NO: 1, and which encode a protein having a cell-recognizing activity and/or a cytopathic activity in an activated form.

Abstract: A lithographic type diffusion transfer developing composition which provides high contrast images having sharp toe-gradation for developing silver halide light-sensitive materials contains at least one amine represented by one of the following general formulae (I), (II) or (III):H.sub.2 N-C.sub.n H.sub.2n -X (I) ##STR1## X, X', R.sub.1, n and m are defined in the specification. The process of developing using such a composition is also disclosed.

Abstract: A printing plate having an improved durability which has a support having an oleophilic surface and a hydrophilic diffusion transfer image-receiving layer containing nucleus substance for the physical development and having between the oleophilic and hydrophilic layers at least one of gelatin or nitrocellulose.

Abstract: Developer compositions for diffusion transfer photographic materials containing amino compounds and imidazole compounds are used in a diffusion transfer photographic process for obtaining litho-type positive images of high contrast and of good short toe effect, the amino compounds being represented by the following formula I and the imidazole compounds by the following formula II:formula I(a) NH.sub.2 --C.sub.m H.sub.2m --Xwherein X represents a hydrogen atom, hydroxyl group, carboxyl group or amino group, and m represents a natural number of 0-12, but X represents a hydroxyl group when m is 0, ##STR1## wherein X and X' represent each a hydrogen atom, hydroxyl group, carboxyl group or amino group, and m and each represents a natural number of 0-12, but X and/or X' represents a hydroxyl group when m and/or n is 0. ##STR2## WHEREIN Y represents an oxygen atom, --CH.sub.

Abstract: A method of stabilizing a silver halide photographic material containing an image formed therein, said material comprising a silver halide emulsion on a support and having at least one member selected from the group consisting of iodine and an iodine containing inorganic compound in said silver halide emulsion or in an adjacent layer to said silver halide emulsion, comprising heating said photographic material.

Abstract: A photosensitive printing plate having excellent reproducibility of an original of continuous tone comprising a support having an oleophilic surface and formed thereon a diffusion transfer hydrophilic image-receiving layer containing nucleating materials for physical development and a photosensitive silver halide emulsion layer, said image-receiving layer containing an alginate or an image-receiving subsidiary layer containing an alginate present between said image-receiving layer and said photosensitive emulsion layer.

Abstract: A diffusion transfer image-receptive sheet comprising (a) a sheet of an alkali impermeable polymer having a surface portion converted into an alkali permeable state and (b) diffusion transfer nuclei incorporated in the alkali permeable surface portion.

Abstract: A printing plate having halftones and lines is produced by exposing a photosensitive printing plate material comprising a support having an oleophilic surface, a hydrophilic layer formed thereon and a layer of a direct positive-type photosensitive silver halide emulsion formed on top of the hydrophilic layer through a positive original, developing the exposed material to form a silver image in the emulsion layer, subjecting the developed material to an etch bleaching treatment to remove the hydrophilic layer at portions corresponding to the silver image and to reveal the oleophilic surface, and removing the emulsion layer at a portion on which the silver image is not formed, thereby to reveal said hydrophilic layer. The printing plate can given a number of good quality impressions from the outset of printing, and smeared impressions do not result during continued printing operation.

Abstract: A thermodevelopable photographic material comprising a support and a layer composed of (a) a high silver ion conducting substance having an ion conductivity at 25.degree.C of at least 1 .times. 10.sup.-.sup.3 (.OMEGA.cm).sup.-.sup.1, such as silver iodide tungstate, or a mixture of the high silver ion conducting substance with silver, and (b) a weak reducing agent. In order to increase the sensitivity of the material, a photosensitive silver halide can further be incorporated in the layer. The photographic material is exposed imagewise, and then heated for a short time to form a permanent visible image of clear contrast.