Abstract: A press-through pack and a sealing sheet for use in the same capable of easily taking out solid material such as tablet or the like contained storage recesses by only pushing action of fingers. The pack comprises an accommodation body (2) with plural storage recesses (2a) defined by sheet like portions (2b) for a containing solid material therein and sealing sheet (5). The sealing sheet (5) is made of such material that a recess (2a) in which solid material (T) contained, is partly ruptured without causing floating and peeling at the adhesion portion of the adhesive layer (4) and the sheet like portions (2b) when pushing the projecting portion (2c) of the outer side of the recess (2a) with fingers, whereby the solid material (T) contained in the recess (2a) is easily taken out and the sealing sheet is partially bonded to the accommodation body at sheet like portions (2b) in a manner that the whole parts of sealing sheet (5) is easily peeled off from the accommodation body.

Abstract: Thermally imageable elements useful in lithographic printing are disclosed. The element has a layer of an imageable composition over a support. The imageable composition contains a supramolecular polymer that includes QHB-modified polymeric molecules having the structure A-L-B. A and B are each different QHB-modified portions selected from QHB-modified phenolic portions, QHB-modified acrylic portions, QHB-modified polyester portions, and QHB-modified polyurethane portions. L is a joining group. The elements are suitable for the preparation of lithographic printing plates.

Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 &mgr;m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.

Abstract: A press-through pack and a sealing sheet for use in the same capable of easily taking out solid material such as tablet or the like contained storage recesses by only pushing action of fingers. The pack comprises an accommodation body (2) with plural storage recesses (2a) defined by sheet like portions (2b) for a containing solid material therein and sealing sheet (5). The sealing sheet (5) is made of such material that a recess (2a) in which solid material (T) contained, is partly ruptured without causing floating and peeling at the adhesion portion of the adhesive layer (4) and the sheet like portions (2b) when pushing the projecting portion (2c) of the outer side of the recess (2a) with fingers, whereby the solid material (T) contained in the recess (2a) is easily taken out and the sealing sheet is partially bonded to the accommodation body at sheet like portions (2b) in a manner that the whole parts of sealing sheet (5) is easily peeled off from the accommodation body.

Abstract: The present invention relates to a lithographic printing plate in which images can be inscribed by laser beams, and which has high resolving power, high sensitivity, and the improved reservation stability, and relates to its image-producing method, and a photosenstitive composition which can preferably be used as an original plate for lithographic printing. The photosenstitive composition includes an aqueous resin composition including fine particles (a) of a resin having at least one neutralized anionic group and having a heat fusion property, and a water soluble resin (b) having at least one neutralized anionic group, wherein the water soluble resin (b) is included in a range of 1 to 30% by weight, relative to the total weight of the aqueous resin composition; and a substance (c) which absorbs light and generates heat.

Abstract: The present invention provides an imageable composition, which includes an acid curable composition, an acid generator, an infrared absorber, optionally a colorant, such as, a colorant dye or colorant pigment, wherein at least one of the infrared absorber and the colorant has a counter anion derived from a non-volatile acid, and further optionally, a strong acid. The present invention further provides an imageable element, which includes a substrate and an imageable composition according to the present invention coated on a surface of the substrate. Also provided is method of producing an imaged element according to the present invention.

Abstract: The present invention provides a negative-working photosensitive composition which can widen the preheat latitude upon exposure without increasing ablation, and a negative-working photosensitive lithographic printing plate. The negative-working photosensitive composition comprises (a) an alkali-soluble resin, (b) a compound capable of being crosslinked by an acid, (c) a compound capable of generating an acid by heat, (d) a photothermal converting agent, and (e) a sulfone compound represented by the following general formula (I).

Abstract: The present invention provides a photosensitive lithographic printing plate with a long press life, high sensitivity, and excellent storage stability, and a photosensitive composition for a lithographic printing plate for producing such a photosensitive lithographic printing plate. The photosensitive composition for the lithographic printing plate includes (A) a binder resin, (B) a diazo resin, (C) a monomer or oligomer, a molecule of which has at least two polymerizable ethylenically unsaturated double bonds, (D) a photopolymerization initiator, (E) an o-tert-butylphenol derivative, and (F) a 2-mercaptoimidazole derivative such as 2-mercaptobenzimidazole.

Abstract: The present invention includes a two-layer imageable element, including: a substrate, a top layer including a first thermally imageable composition including (a) a first thermally sensitive supramolecular polymer or (b) a thermally imageable composition free of the first thermally sensitive supramolecular polymer; and disposed between the substrate and the top layer, a bottom layer including a second thermally imageable composition, which includes a second thermally sensitive supramolecular polymer. The present invention also includes a method of producing the imaged element.

Abstract: The photosensitive printing plate of the present invention comprises a substrate, a photosensitive layer formed on the substrate, and mat particles formed on the photosensitive layer, wherein the mat particles contain a copolymer which contains at least one (meth)acrylamides as a unit. The method of producing the photosensitive printing plate of the present invention is a method which comprises the steps of forming a photosensitive layer on a substrate, and coating the photosensitive layer with a solution prepared by dissolving a copolymer containing at least one (meth)acrylamides as a unit in a solvent to form mat particles. The photosensitive printing plate of the present invention has excellent vacuum contact properties and resistance to friction and pressure and is free from tack on the surface when used, avoids problems in developing properties during long storage times, and is superior in terms of solubility in an exhausted developer.

Abstract: A method for producing tablet including active component, diluting agent, and lubricant by means of a tabletting machine provided with punches and dies, comprising steps of; preparing molding material including active component, diluting anent, and a part of lubricant; applying most of the remaining amount of the lubricant on surfaces of the punches and a surface of the die; and tabletting the molding material by means of the punches on which surfaces the lubricant is applied and the die on which surface the lubricant is applied

Abstract: A dividable tablet is not chipped, can be divided easily and accurately, has excellent impact resistance and rarely causes twining in the film-coating step, wherein a dividing line is formed along a center line on the upper surface of the tablet, ridgelines are each located on an inner side of the peripheral portion of the tablet to surround the dividing line in two areas defined by the dividing line on the upper surface of the tablet, the lower surface of the tablet gradually rises from the peripheral portion of the tablet toward the center portion thereof, and areas around the ridgelines are each formed by a convex surface.

Abstract: The present invention relates to a lithographic printing plate in which images can be inscribed by laser beams, and which has high resolving power, high sensitivity, and the improved reservation stability, and relates to its image-producing method, and a photosenstitive composition which can preferably be used as an original plate for lithographic printing. The photosenstitive composition includes an aqueous resin composition including fine particles (a) of a resin having at least one neutralized anionic group and having a heat fusion property, and a water soluble resin (b) having at least one neutralized anionic group, wherein the water soluble resin (b) is included in a range of 1 to 30% by weight, relative to the total weight of the aqueous resin composition; and a substance (c) which absorbs light and generates heat.

Abstract: The present invention provides a tablet containing isotope-labeled urea and an inorganic compound.

Abstract: A tablet comprising sugar alcohol or saccaride having an average particle diameter of not more than 30 &mgr;m, an active ingredient, and a disintegrant. It is an intraorally rapidly disintegrable tablet which does not require a special pharmaceutical manufacturing technology and can be simply and easily produced by a normal equipment.

Abstract: The present invention relates to a solid dispersion and a solid dispersion dosage form which comprise a xanthine derivative represented by the following formula (I) or a pharmacologically allowable salt thereof and a polymer. (In the above formula, R1 and R2 are the same or different, and represent substituted or unsubstituted lower alkyl groups, and Q represents a hydrogen atom or a hydroxyl group.

Abstract: A storage stable dessicated composition is formed of a DX-52-1 derivative according to Formula (I) ##STR1## and at least one saccharide. The composition may be formed by lyophilizing a composition which preferably has a pH of 7-12.

Abstract: A photosensitive composition which comprises a resin (A) having urea bonds in its side chains and a photosensitive compound (B), wherein the resin (A) contains at least one resin selected from the group consisting of a vinyl polymer resin and a condensation polymer resin, provides a coating layer with excellent resistance to solvents and abrasion. The photosensitive composition is suitable for use in the production of planographic printing plates, integrated circuits (IC) or photomasks. A photosensitive planographic printing plate produced usig the photosensitive composition has superior press-life.

Abstract: Stabilized duocarmycin derivatives represented by formula (I): ##STR1## wherein R is lower alkyl, allyl or benzyl, and X is Cl or Br, are prepared by adding at least a compound selected from the group consisting of a saccharide, an electrolyte, a water-soluble polymer, a polyhydric alcohol and a surfactant to a solution containing the duocarmycin derivatives. Also provided are freeze-dried pharmaceutical preparations containing the stabilized duocarmycin derivatives.

Abstract: Topical ophthalmic formulations of the invention contain as an active ingredient 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid or a pharmaceutically acceptable salt thereof. The formulations are useful for treating allergic eye diseases such as allergic conjunctivitis, vernal conjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis.