Patents by Inventor Eiji Kimura

Eiji Kimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF
    Publication number: 20260146047
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: January 20, 2026
    Publication date: May 28, 2026
    Inventors: Mitsunori KONO, Yusuke SASAKI, Yuya OGURO, Zenichi IKEDA, Osamu KUBO, Masaki SETO, Toru YAMASHITA, Makoto KAMATA, Kenjiro SATO, Matthew Thomas REYNOLDS, Kazuaki TAKAMI, Asato KINA, Takafumi YUKAWA, Minoru NAKAMURA, Taku KAMEI, Hiroyuki KAKEI, Fumie YAMAGUCHI, Tomohiro OHASHI, Keiko KAKEGAWA, Takuto KOJIMA, Florian PÜNNER, Masataka MURAKAMI, Takahiko TANIGUCHI, Tatsuki KOIKE, Yuichi KAJITA, Yuhei MIYANOHANA, Kohei TAKEUCHI, Yoshiteru ITO, Norihito TOKUNAGA, Yasushi HATTORI, Eiji KIMURA, Martin Alexander PAWLICZEK, Marilena PIRA, Shuhei IKEDA, Noriyuki TEZUKA, Yoshikazu WATANABE, Kevin CURRAN, Nicolle DOERING, Maria HOPKINS, Ben JOHNSON, Andre KIRYANOV, Jon LAM, Sean MURPHY, Natasha O'ROURKE, Holly REICHARD, Paul TANIS, Yunlong ZHANG
  • Pyrrolo[1, 2-c]imidazole derivatives as orexin type 2 receptor agonists and methods of use thereof
    Patent number: 12534471
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: January 27, 2026
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yasushi Hattori, Marilena Pira, Yoshiteru Ito, Kohei Takeuchi, Eiji Kimura, Norihito Tokunaga, Shuhei Ikeda, Martin Alexander Pawliczek, Noriyuki Tezuka, Yasutaka Hoashi, Yuhei Miyanohana, Yuichi Kajita, Tatsuki Koike
  • Heterocyclic compound
    Patent number: 12448377
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Grant
    Filed: November 26, 2020
    Date of Patent: October 21, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yoshiteru Ito, Yuhei Miyanohana, Yuichi Kajita, Yasutaka Hoashi, Yasushi Hattori, Tatsuki Koike, Norihito Tokunaga, Eiji Kimura, Alexander Martin Pawliczek, Marilena Pira, Javier Miguelez-Ramos
  • Disc brake pad
    Patent number: 12385541
    Abstract: [Object] To provide the disc brake pad including the friction material having the friction surface with the scorch treatment that can provide sufficient braking effectiveness while preventing the fading phenomenon at the initial stage of the disc brake pad usage. [Means to Resolve] In the disc brake pad including the friction material having the friction surface with the heat history due to the scorch treatment, the friction surface has the mixed areas including the area with the large heat history of the scorch treatment and the area with relatively small heat history of the scorch treatment.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 12, 2025
    Assignee: NISSHINBO BRAKE, INC.
    Inventors: Eiji Kimura, Mitsuaki Yaguchi, Yasuki Hattori
  • HETEROCYCLIC COMPOUND
    Publication number: 20250250230
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I) is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: April 12, 2022
    Publication date: August 7, 2025
    Inventors: Shuhei IKEDA, Martin Alexander PAWLICZEK, Eiji KIMURA, Yasushi HATTORI, Marilena PIRA, Javier MIGUELEZ-RAMOS, Norihito TOKUNAGA, Yuhei MIYANOHANA, Yasutaka HOASHI, Yuichi KAJITA, Yoshiteru ITO, Tasuki KOIKE
  • UNDERLAYER FOR DISC BRAKE PAD AND DISC BRAKE PAD USING THE UNDERLAYER
    Publication number: 20250075763
    Abstract: To provide the underlayer for a disc brake pad, which is positioned between a back plate and a friction material providing excellent brake noise suppression effect. The underlayer composition contains 5-15 weight % of the uncrosslinked fluororubber relative to the entire amount of the underlayer composition, 4-8 weight % of the phenol-based resin as the binder relative to the entire amount of the underlayer composition, and 0.3-2 weight % of the hexamethylenetetramine as the curing agent for the phenol-based resin relative to the entire amount of the underlayer composition.
    Type: Application
    Filed: October 10, 2024
    Publication date: March 6, 2025
    Applicant: NISSHINBO BRAKE, INC.
    Inventor: Eiji Kimura
  • SPOILER DEVICE
    Publication number: 20240351645
    Abstract: A spoiler device is adapted to be installed on a rear edge of a vehicle body component arranged on a vehicle and includes a spoiler body having an upper surface portion and a bent portion bent downward from a rear end of the upper surface portion and a movable mechanism connected to the spoiler body to drive the spoiler body to move relative to the vehicle body component. The spoiler body is movable between a storing position where a front end of the upper surface portion is close to an upper surface of the vehicle body component and an extending position where the upper surface portion extends rearward relative to the vehicle body component via the movable mechanism. Taking an imaginary line extending along the upper surface as a reference, the front end in the extending position is located on or further downward than the imaginary line.
    Type: Application
    Filed: March 19, 2024
    Publication date: October 24, 2024
    Applicant: Honda Motor Co., Ltd.
    Inventors: Yuki NAKAMURA, Kei AMBO, Eiji KIMURA, Hiroyuki HAZAWA, Shinichi OZAKI, Satoru KUCHIKI, Shogo DEHARA, Shuji NAKA
  • HETEROCYCLIC COMPOUND
    Publication number: 20240317765
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: April 8, 2024
    Publication date: September 26, 2024
    Inventors: Yasushi HATTORI, Marilena PIRA, Yoshiteru ITO, Kohei TAKEUCHI, Eiji KIMURA, Norihito TOKUNAGA, Shuhei IKEDA, Martin Alexander PAWLICZEK, Noriyuki TEZUKA, Yasutaka HOASHI, Yuhei MIYANOHANA, Yuichi KAJITA, Tatsuki KOIKE
  • MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF
    Publication number: 20240309016
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: March 15, 2024
    Publication date: September 19, 2024
    Inventors: Mitsunori KONO, Yusuke SASAKI, Yuya OGURO, Zenichi IKEDA, Osamu KUBO, Masaki SETO, Toru YAMASHITA, Makoto KAMATA, Kenjiro SATO, Matthew Thomas REYNOLDS, Kazuaki TAKAMI, Asato KINA, Takafumi YUKAWA, Minoru NAKAMURA, Taku KAMEI, Hiroyuki KAKEI, Fumie YAMAGUCHI, Tomohiro OHASHI, Keiko KAKEGAWA, Takuto KOJIMA, Florian PÜNNER, Masataka MURAKAMI, Takahiko TANIGUCHI, Tatsuki KOIKE, Yuichi KAJITA, Yuhei MIYANOHANA, Kohei TAKEUCHI, Yoshiteru ITO, Norihito TOKUNAGA, Yasushi HATTORI, Eiji KIMURA, Martin Alexander PAWLICZEK, Marilena PIRA, Shuhei IKEDA, Noriyuki TEZUKA, Yoshikazu WATANABE, Kevin CURRAN, Nicolle DOERING, Maria HOPKINS, Ben JOHNSON, Andre KIRYANOV, Jon LAM, Sean MURPHY, Natasha O'ROURKE, Holly REICHARD, Paul TANIS, Yunlong ZHANG
  • HETEROCYCLIC COMPOUND
    Publication number: 20240174677
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: October 30, 2023
    Publication date: May 30, 2024
    Inventors: Yasushi HATTORI, Marilena PIRA, Yoshiteru ITO, Kohei TAKEUCHI, Eiji KIMURA, Norihito TOKUNAGA, Shuhei IKEDA, Martin Alexander PAWLICZEK, Noriyuki TEZUKA, Yasutaka HOASHI, Yuhei MIYANOHANA, Yuichi KAJITA, Tatsuki KOIKE
  • Pyrrolo[1,2-c]imidazole derivatives as orexin type 2 receptor agonists
    Patent number: 11987586
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Grant
    Filed: October 30, 2023
    Date of Patent: May 21, 2024
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yasushi Hattori, Marilena Pira, Yoshiteru Ito, Kohei Takeuchi, Eiji Kimura, Norihito Tokunaga, Shuhei Ikeda, Martin Alexander Pawliczek, Noriyuki Tezuka, Yasutaka Hoashi, Yuhei Miyanohana, Yuichi Kajita, Tatsuki Koike
  • Heterocyclic compound
    Patent number: 11713311
    Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: August 1, 2023
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Eiji Kimura, Masaki Ogino, Yasuhisa Kohara, Tomoko Ohashi, Tomohiro Kaku, Yuya Oguro, Shigemitsu Matsumoto, Takeshi Wakabayashi, Norihito Tokunaga, Taku Kamei, Mitsuhiro Ito
  • HETEROCYCLIC COMPOUND
    Publication number: 20230037557
    Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
    Type: Application
    Filed: November 26, 2020
    Publication date: February 9, 2023
    Inventors: Yoshiteru ITO, Yuhei MIYANOHANA, Yuichi KAJITA, Yasutaka HOASHI, Yasushi HATTORI, Tatsuki KOIKE, Norihito TOKUNAGA, Eiji KIMURA, Alexander Martin PAWLICZEK, Marilena PIRA, Javier MIGUELEZ-RAMOS
  • HETEROCYCLIC COMPOUND
    Publication number: 20220388995
    Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: December 14, 2021
    Publication date: December 8, 2022
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Eiji KIMURA, Masaki OGINO, Yasuhisa KOHARA, Tomoko OHASHI, Tomohiro KAKU, Yuya OGURO, Shigemitsu MATSUMOTO, Takeshi WAKABAYASHI, Norihito TOKUNAGA, Taku KAMEI, Mitsuhiro ITO
  • DISC BRAKE PAD
    Publication number: 20220373052
    Abstract: [Object] To provide the disc brake pad including the friction material having the friction surface with the scorch treatment that can provide sufficient braking effectiveness while preventing the fading phenomenon at the initial stage of the disc brake pad usage. [Means to Resolve] In the disc brake pad including the friction material having the friction surface with the heat history due to the scorch treatment, the friction surface has the mixed areas including the area with the large heat history of the scorch treatment and the area with relatively small heat history of the scorch treatment.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 24, 2022
    Applicant: NISSHINBO BRAKE, INC.
    Inventors: EIJI KIMURA, MITSUAKI YAGUCHI, YASUKI HATTORI
  • Method for manufacturing friction material
    Patent number: 11473638
    Abstract: [Object] To provide the method of manufacturing the friction material that is capable of uniformly scorching into the deep part of the surface layer of the friction material in a short period of time. [Means to Resolve] In the method of manufacturing the friction material including the scorching step of scorching the surface of the friction material with the laser, the friction material contains 5 to 25% by weight of one or more types of black materials relative to the total amount of the friction material composition, and the L* of the CIE Lab of the surface of the friction material before scorching is 20 to 60.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: October 18, 2022
    Assignee: Nisshinbo Brake, Inc.
    Inventors: Eiji Kimura, Mitsuaki Yaguchi, Junichi Imai
  • Wire bonding method and wire bonding device
    Patent number: 11404393
    Abstract: A wire bonding method includes bringing a capillary and a wire inserted through the capillary into pressure contact with a bonding point of a lead placed on an XY stage to bond the wire to the lead, including moving the XY stage in a state in which the capillary is in pressure contact with the lead to move the capillary along a movement locus including a plurality of arc portions.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: August 2, 2022
    Assignee: KAIJO CORPORATION
    Inventors: Eiji Kimura, Hiroaki Suzuki, Yoshikazu Tashiro
  • UNDERLAYER COMPOSITION FOR DISC BRAKE PAD AND DISC BRAKE PAD USING THE UNDERLAYER COMPOSITION
    Publication number: 20220196096
    Abstract: [Object] To provide the underlayer composition for the disc brake pad, which may be applicable to the manufacturing process of softening the rubber by heating even if the uncrosslinked fluororubber in the underlayer composition and the disc brake pad with an excellent brake noise suppression effect. [Means to Resolve] To use the underlayer composition containing 5-15 weight % of the uncrosslinked fluororubber relative to the entire amount of the underlayer composition, 4-8 weight % of the phenol-based resin as the binder relative to the entire amount of the underlayer composition, and 0.3-2 weight % of the hexamethylenetetramine as the curing agent for the phenol-based resin relative to the entire amount of the underlayer composition.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 23, 2022
    Applicant: NISSHINBO BRAKE, INC.
    Inventor: Eiji Kimura
  • Crystal device and electronic apparatus using this crystal device
    Patent number: 11251770
    Abstract: A crystal device includes a rectangular shaped substrate, a mounting frame which is along an outer circumferential edge of a lower surface of the substrate on its short-side sides and configures a recessed part, electrode pads on an upper surface of the substrate, connection pads on the lower surface of the substrate in the mounting frame, a crystal element mounted on the electrode pads, a temperature sensing element mounted on the connection pads, and a lid air-tightly sealing the crystal element. The electrode pads and the recessed part do not overlap in a plane perspective view.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: February 15, 2022
    Assignee: KYOCERA CORPORATION
    Inventors: Eiji Kimura, Tsuyoshi Teramura
  • Heterocyclic compound
    Patent number: 11230541
    Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: January 25, 2022
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Eiji Kimura, Masaki Ogino, Yasuhisa Kohara, Tomoko Ohashi, Tomohiro Kaku, Yuya Oguro, Shigemitsu Matsumoto, Takeshi Wakabayashi, Norihito Tokunaga, Taku Kamei, Mitsuhiro Ito