Patents by Inventor Eiji Morikawa

Eiji Morikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINAZOLINE COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS PROTEIN
    Publication number: 20240182483
    Abstract: [Problem] To provide a compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer. [Means for resolution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a quinazoline compound has an excellent degradation-inducing action on a G12D mutant KRAS protein and a G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The quinazoline compound or a salt thereof of the present invention can be used as a therapeutic agent for pancreatic cancer.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 6, 2024
    Inventors: Tomohiro YOSHINARI, Hiroki ISHIOKA, Eiji KAWAMINAMI, Hideyuki WATANABE, Kenichi KAWAGUCHI, Kazuyuki KURAMOTO, Tomoyoshi IMAIZUMI, Takahiro MORIKAWA, Hisao HAMAGUCHI, Sunao IMADA, Mitsuaki OKUMURA, Takeyuki NAGASHIMA, Kohei INAMURA
  • 4-AMINOQUINAZOLINE COMPOUND
    Publication number: 20240150366
    Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 9, 2024
    Inventors: Kenichi KAWAGUCHI, Kazuyuki KURAMOTO, Tomoyoshi IMAIZUMI, Takahiro MORIKAWA, Mitsuaki OKUMURA, Sunao IMADA, Eiji KAWAMINAMI, Ryo SATO, Yohei SEKI, Hisao HAMAGUCHI, Hiroki ISHIOKA, Hiroki FUKUDOME, Ikumi KURIWAKI, Takeyuki NAGASHIMA
  • Multiple speaker
    Patent number: 4401857
    Abstract: A piezoelectric cone-type speaker having a multiple structure in which a plurality of piezoelectric elements and speaker diaphragms individually coupled to them are coaxially or multi-axially arranged. It has a wide frequency range. A cushioning member is interposed between one diaphragm and another so that each element is isolated from the vibrations of another element.
    Type: Grant
    Filed: November 19, 1981
    Date of Patent: August 30, 1983
    Assignee: Sanyo Electric Co., Ltd.
    Inventor: Eiji Morikawa
  • Acoustic transducer
    Patent number: 4389548
    Abstract: In an acoustic transducer comprising a piezoelectric element for driving a speaker diaphragm, there is provided a cushioning member between a frame body and the piezoelectric element wherein said cushioning member is preliminarily adhered onto the top face of a bottom portion of the frame body by means of an adhering layer formed on the bottom face of the cushioning member with the piezoelectric element preliminarily adhered on the top face of the cushioning member by means of an adhering layer formed on the top face of the cushioning member so as to facilitate to mount the piezoelectric element and a speaker diaphragm on the frame body.
    Type: Grant
    Filed: March 27, 1981
    Date of Patent: June 21, 1983
    Assignee: Sanyo Electric Co., Ltd.
    Inventors: Eiji Morikawa, Toshifumi Morita, Masayuki Hirate