Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: Magnets (20) are separated by ferromagnetic plates (21) from an inner surface of a brake drum (13) made of steel and secured to a rotational shaft (4). When the rotating brake drum (13) crosses magnetic flux generated by the magnets (20), a braking force caused by eddy currents is produced in the brake drum (13). An annular body (41) formed of a good conductor such as copper is fastened adjacent to at least one side surface of the brake drum (13) in a position axially spaced from the plates (21).

Abstract: There is disclosed a deodorizer which comprises a colloidal antimony pentoxide. A surface of the colloidal antimony pentoxide may be modified by a metal compound, ammonia or an organic base and it may be further modified by an acidic substance.The deodorizer of the present invention is effective to deodorize a basic gas such as ammonia, trimethylamine, triethylamine, etc.; an acidic gas such as hydrogen sulfide, acetic acid, butyric acid, isovaleric acid, methymercaptane, ethylmercaptane, methyl sulfide, methyl disulfide, etc.; an organic solvent gas such as tolunene, ethylacetate, methyl ethyl ketone, benzene acetaldehyde, etc.; and further to alleviate uncomfortable for example, odor causing gas daily generated such as nicotine smell, tar small, etc.

Abstract: A chemical grout for ground injection which is prepared by incorporating from 0.1 to 4.5 parts by weight of sulfamic acid and from 0.2 to 10.0 parts by weight of a water soluble magnesium salt into 100 parts by weight of an aqueous sol having a pH of 8 to 10.5 and containing from 5 to 25% by weight of colloidal silica (as SiO.sub.2) having a particle size of 3 to 7 m.mu., and from 0.05 to 1.5% by weight of Na.sub.2 O. This injecting grout has a gelation time not longer than 300 minutes. Soft ground can be consolidated by using the grout.