Patents by Inventor Eiji Sakuradani

Eiji Sakuradani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538793
    Abstract: Provided is ?3 desaturase having high enzymatic activity even at normal temperature. A polypeptide which consists of an amino acid sequence having an identity of 80% or more with the amino acid sequence represented by SEQ ID NO: 2 and has ?3 desaturation activity on C20 fatty acid, and a gene thereof.
    Type: Grant
    Filed: December 24, 2015
    Date of Patent: January 21, 2020
    Assignees: KYOTO UNIVERSITY, NISSHIN PHARMA INC.
    Inventors: Jun Ogawa, Akinori Ando, Eiji Sakuradani, Sakayu Shimizu, Shigeru Hiramoto, Masataka Harata, Yuki Takemoto
  • Patent number: 10323250
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains any one nucleotide sequence selected from the group consisting of SEQ ID NO: 1 to 28, or a variant thereof.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: June 18, 2019
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Misa Ochiai, Jun Ogawa, Eiji Sakuradani, Akinori Ando
  • Publication number: 20190112613
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains any one nucleotide sequence selected from the group consisting of SEQ ID NOs: 1 to 28, or a variant thereof.
    Type: Application
    Filed: September 19, 2018
    Publication date: April 18, 2019
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Jun OGAWA, Eiji SAKURADANI, Akinori ANDO
  • Patent number: 10113173
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains any one nucleotide sequence selected from the group consisting of SEQ ID NOs: 1 to 28, or a variant thereof.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: October 30, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Misa Ochiai, Jun Ogawa, Eiji Sakuradani, Akinori Ando
  • Publication number: 20180087061
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains any one nucleotide sequence selected from the group consisting of SEQ ID NOs: 1 to 28, or a variant thereof.
    Type: Application
    Filed: August 14, 2017
    Publication date: March 29, 2018
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Jun OGAWA, Eiji SAKURADANI, Akinori ANDO
  • Publication number: 20170369909
    Abstract: Provided is ?3 desaturase having high enzymatic activity even at normal temperature. A polypeptide which consists of an amino acid sequence having an identity of 80% or more with the amino acid sequence represented by SEQ ID NO: 2 and has ?3 desaturation activity on C20 fatty acid, and a gene thereof.
    Type: Application
    Filed: December 24, 2015
    Publication date: December 28, 2017
    Applicants: KYOTO UNIVERSITY, NISSHIN PHARMA INC.
    Inventors: Jun OGAWA, Akinori ANDO, Eiji SAKURADANI, Sakayu SHIMIZU, Shigeru HIRAMOTO, Masataka HARATA, Yuki TAKEMOTO
  • Patent number: 9765345
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains a nucleotide sequence selected from SEQ ID NOs: 1 to 28, or a variant thereof, as well as a non-human transformant containing such a polynucleotide.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: September 19, 2017
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Misa Ochiai, Jun Ogawa, Eiji Sakuradani, Akinori Ando
  • Publication number: 20160208297
    Abstract: Provided is an ?3 desaturase having a high enzymatic activity even at normal temperature. A polypeptide consisting of an amino acid sequence having an identity of 80% or more with the amino acid sequence represented by SEQ ID NO: 2 and having ?3 desaturation activity, and a gene therefor.
    Type: Application
    Filed: August 26, 2014
    Publication date: July 21, 2016
    Applicants: KYOTO UNIVERSITY, NISSHIN PHARMA INC.
    Inventors: Jun OGAWA, Eiji SAKURADANI, Akinori ANDO, Sakayu SHIMIZU, Masataka HARATA, Shigeru HIRAMOTO
  • Publication number: 20160152992
    Abstract: The present invention aims to provide a promoter showing high expression activity in microorganisms belonging to the genus Mortierella. The present invention provides a polynucleotide which contains any one nucleotide sequence selected from the group consisting of SEQ ID NOs: 1 to 28, or a variant thereof.
    Type: Application
    Filed: March 26, 2014
    Publication date: June 2, 2016
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Jun OGAWA, Eiji SAKURADANI, Akinori ANDO
  • Patent number: 9051590
    Abstract: The present invention provides a novel acetyl-CoA carboxylase. The object of the present invention is attained by the nucleotide sequence of SEQ ID NO: 1 and the amino acid sequence of SEQ ID NO: 2 of the present invention.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: June 9, 2015
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Misa Ochiai, Eiji Sakuradani, Sakayu Shimizu, Jun Ogawa
  • Publication number: 20120264960
    Abstract: The present invention provides a novel acetyl-CoA carboxylase. The object of the present invention is attained by the nucleotide sequence of SEQ ID NO: 1 and the amino acid sequence of SEQ ID NO: 2 of the present invention.
    Type: Application
    Filed: March 17, 2010
    Publication date: October 18, 2012
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa Ochiai, Eiji Sakuradani, Sakayu Shimizu, Jun Ogawa
  • Patent number: 7615364
    Abstract: The present invention provides a polypeptide having a wide substrate specificity and having a ?3 fatty acid desaturation activity, which makes efficiently unsaturated bond at ?3 position, and a polynucleotide coding for the same. By expressing the polypeptide in the organism, mass production of n-3 series PUFAs is enabled. Specifically, the polypeptide having a ?3 fatty acid desaturation activity and consisting of the amino acid sequence represented by SEQ ID NO: 1, a polynucleotide coding for a polypeptide having a ?3 fatty acid desaturation activity that consists of the base sequence represented by SEQ ID NO: 2 or SEQ ID NO: 3, and the like is useful for production of n-3 series fatty acids.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: November 10, 2009
    Assignee: Suntory Holdings Limited
    Inventors: Sakayu Shimizu, Eiji Sakuradani
  • Publication number: 20080269329
    Abstract: In a process for the production of diacylglycerol-containing fat/oil where the ratio of diacylglycerol to the total neutral lipid is more than 20% by weight and a polyunsaturated fatty acid is a constituting fatty acid, a process which is characterized in that a microbe being able to produce said fat/oil is incubated and, if desired, said fat/oil is collected.
    Type: Application
    Filed: August 19, 2005
    Publication date: October 30, 2008
    Inventors: Shigeaki Fujikawa, Eiji Sakuradani, Jun Ogawa, Sakayu Shimizu
  • Publication number: 20080153142
    Abstract: The invention provides a process, for producing fats or oils in which the rate of triglycerides constituted by the same polyunsaturated fatty acids linking to the three hydroxyl groups of glycerol is 20% or more by weight for the total triglycerides, which comprises culturing a microorganism capable of producing said fats or oils and if required recovering said fats or oils; fats or oils produced by this process; and a process for producing said fats or oils.
    Type: Application
    Filed: August 18, 2005
    Publication date: June 26, 2008
    Inventors: Hiroshi Kawashima, Eiji Sakuradani, Jun Ogawa, Sakayu Shimizu
  • Publication number: 20080138874
    Abstract: A method of breeding a lipid-producing strain belonging to the genus Mortierella. According to the method of breeding a lipid-producing strain which involves an expression-inhibiting step of inhibiting the expression of a specific gene in the lipid-producing strain as described above, a lipid-producing strain belonging to the genus Mortierella can be efficiently and effectively bred.
    Type: Application
    Filed: March 28, 2005
    Publication date: June 12, 2008
    Inventors: Misa Ochiai, Hiroshi Kawashima, Sakayu Shimizu, Eiji Sakuradani
  • Publication number: 20080032335
    Abstract: The present invention provides a polypeptide having a wide substrate specificity and having a ?3 fatty acid desaturation activity, which makes efficiently unsaturated bond at ?3 position, and a polynucleotide coding for the same. By expressing the polypeptide in the organism, mass production of n-3 series PUFAs is enabled. Specifically, the polypeptide having a ?3 fatty acid desaturation activity and consisting of the amino acid sequence represented by SEQ ID NO: 1, a polynucleotide coding for a polypeptide having a ?3 fatty acid desaturation activity that consists of the base sequence represented by SEQ ID NO: 2 or SEQ ID NO: 3, and the like is useful for production of n-3 series fatty acids.
    Type: Application
    Filed: August 19, 2005
    Publication date: February 7, 2008
    Inventors: Sakayu Shimizu, Eiji Sakuradani